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Naphazoline
go.drugbank.com/drugs/DB06711ApprovedNaphazoline was first developed in 1942 as a nasal formulation for congestion[A176609]. … Naphazoline is a rapid acting imidazoline sympathomimetic vasoconstrictor of ocular or nasal artierioles[L5804,L5807].
Mixtures: Cooper A.R., OSMOCROM-N ®Categories: Heterocyclic Compounds, 1-Ring, Adrenergic alpha-1 Receptor AgonistsPropylhexedrine
go.drugbank.com/drugs/DB06714ApprovedPropylhexedrine is an alpha-adrenergic agonist often used in nasal decongestant inhalers. It is used to give temporary relief for nasal congestion from colds, allergic rhinitis, or allergies.
Fosaprepitant
go.drugbank.com/drugs/DB06717ApprovedInvestigationalIt is a prodrug of Aprepitant. It aids in the prevention of acute and delayed nausea and vomiting associated with chemotherapy treatment.
Categories: Substance P/Neurokinin-1 Receptor Antagonist, Neurokinin 1 AntagonistsProducts: PREQUIM-F, EMEND ® IV 150MGSeproxetine
go.drugbank.com/drugs/DB06731ExperimentalSeproxetine is also known as (S)-norfluoxetine. It is a selective serotonin reuptake inhibitor (SSRI). It is an active metabolite of fluoxetine.
Categories: Cytochrome P-450 CYP2C19 Inhibitors, Cytochrome P-450 CYP2C9 InhibitorsSynonyms: (S)-norfluoxetineDrotaverine
go.drugbank.com/drugs/DB06751ApprovedWithdrawnDrotaverine is an antispasmodic drug that works by inhibiting phosphodiesterase-4 (PDE4). … [A231619] It is a benzylisoquinoline derivative that is structurally related to [papaverine], although it displays more potent antispasmodic activities than papaverine.
Categories: Heterocyclic Compounds, 2-Ring, Phosphodiesterase 4 InhibitorsBesifloxacin
go.drugbank.com/drugs/DB06771ApprovedBesifloxacin is a fourth generation fluoroquinolone-type opthalmic antibiotic for the treatment of bacterial conjunctivitis. FDA approved on May 28, 2009.
Categories: 4-Quinolones, Heterocyclic Compounds, 1-RingProducts: BESIVANCE % 0,6 OFTALMIK SÜSPANSIYON, 5 MLChenodeoxycholic acid
go.drugbank.com/drugs/DB06777ApprovedInvestigationalChenodeoxycholic acid is a bile acid naturally found in the body.
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A SubstratesDimercaprol
go.drugbank.com/drugs/DB06782ApprovedIn addition, it has in the past been used for the treatment of Wilson's disease, a genetic disorder in which the body tends to retain copper. … Dimercaprol has toxic potential, and its use may be followed by a variety of adverse effects.
Categories: Compounds used in a research, industrial, or household settingSynonyms: α,β-dithioglycerol, 1,2-dimercapto-3-propanolGanirelix
go.drugbank.com/drugs/DB06785ApprovedInvestigationalGanirelix is a synthetic decapeptide and a competitive gonadotropin-releasing hormone (GnRH) antagonist. Derived from endogenous GnRH, ganirelix has amino acid substitutions.
Products: ORGALUTRAN® 0.25 MG / 0.5 ML SOLUCION INYECTABLE, ORGALUTRAN 0,25 MG/0.5 ML ENJEKSİYONLUK ÇÖZELTİ, 1 ADETHistrelin
go.drugbank.com/drugs/DB06788ApprovedInvestigationalWithdrawnThis drug is a synthetic analog of naturally occurring GnRH with a higher potency. … Histrelin is a gonadotropin-releasing hormone (GnRH) agonist that acts as a potent inhibitor of gonadotropin when administered as an implant delivering continuous therapeutic doses.
Synonyms: 5-oxo-L-prolyl-L-histidyl-L-tryptophyl-L-seryl-L-tyrosyl-1-benzyl-D-histidyl-L-leucyl-L-arginyl-N-ethyl-L-prolinamide, 5-oxo-L-prolyl-L-histidyl-L-tryptophyl-L-seryl-L-tyrosyl-Nτ-benzyl-D-histidyl-L-leucyl-L-arginyl-N-ethyl-L-prolinamide