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3-ketoacyl-CoA thiolase
go.drugbank.com/bio_entities/BE0004257TargetPseudomonas fragiCatalyzes the final step of fatty acid oxidation in which acetyl-CoA is released and the CoA ester of a fatty acid two carbons shorter is formed.
Polypeptides: 3-ketoacyl-CoA thiolaseSH2B adapter protein 3
go.drugbank.com/bio_entities/BE0004714TargetHumansLinks T-cell receptor activation signal to phospholipase C-gamma-1, GRB2 and phosphatidylinositol 3-kinase
Polypeptides: SH2B adapter protein 3Carbonyl reductase [NADPH] 3
go.drugbank.com/bio_entities/BE0004771EnzymeHumansCatalyzes the NADPH-dependent reduction of carbonyl compounds to their corresponding alcohols (PubMed:18493841). Has low NADPH-dependent oxidoreductase activity. Acts on several orthoquinones, acts as well on non-quinone compounds, such ...
Polypeptides: Carbonyl reductase [NADPH] 3Synonyms: NADPH-dependent carbonyl reductase 3, Short chain dehydrogenase/reductase family 21C member 2Tropomyosin alpha-3 chain
go.drugbank.com/bio_entities/BE0009038TargetHumansBinds to actin filaments in muscle and non-muscle cells. Plays a central role, in association with the troponin complex, in the calcium dependent regulation of vertebrate striated muscle contraction. Smooth muscle contraction is regulate...
Polypeptides: Tropomyosin alpha-3 chainSynonyms: Tropomyosin-3Glyceraldehyde-3-phosphate dehydrogenase
go.drugbank.com/bio_entities/BE0009171TargetPlasmodium falciparum (isolate 3D7)Polypeptides: Glyceraldehyde-3-phosphate dehydrogenaseFunction: glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activityRibulose-phosphate 3-epimerase
go.drugbank.com/bio_entities/BE0009671EnzymeHumansCatalyzes the reversible epimerization of D-ribulose 5-phosphate to D-xylulose 5-phosphate
Polypeptides: Ribulose-phosphate 3-epimeraseSynonyms: Ribulose-5-phosphate-3-epimerase5-hydroxytryptamine 3 receptor
go.drugbank.com/bio_entities/BE0009860TargetHumansForms serotonin (5-hydroxytryptamine/5-HT3)-activated cation-selective channel complexes, which when activated cause fast, depolarizing responses in neurons
Synonyms: 5-HT-3, 5-hydroxytryptamine receptor 3Angiopoietin-related protein 3
go.drugbank.com/bio_entities/BE0010034TargetHumansActs in part as a hepatokine that is involved in regulation of lipid and glucose metabolism (PubMed:11788823, PubMed:12909640, PubMed:23661675, PubMed:25495645). Proposed to play a role in the trafficking of energy substrates to either s...
Polypeptides: Angiopoietin-related protein 3Synonyms: Angiopoietin-like protein 3Cyclin-dependent kinase 3
go.drugbank.com/bio_entities/BE0010230TargetHumansSerine/threonine-protein kinase that plays a critical role in the control of the eukaryotic cell cycle; involved in G0-G1 and G1-S cell cycle transitions. Interacts with CCNC/cyclin-C during interphase. Phosphorylates histone H1, ATF1, R...
Polypeptides: Cyclin-dependent kinase 3Synonyms: Cell division protein kinase 35-hydroxytryptamine receptor 3
go.drugbank.com/bio_entities/BE0010272TargetHumansForms serotonin (5-hydroxytryptamine/5-HT3)-activated cation-selective channel complexes, which when activated cause fast, depolarizing responses in neurons
Synonyms: 5-HT-3, 5-hydroxytryptamine receptor 3