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Inactive phospholipase C-like protein 1
go.drugbank.com/bio_entities/BE0001081TargetHumansComponent in the phospho-dependent endocytosis process of GABA A receptor (By similarity). … Involved in an inositol phospholipid-based intracellular signaling cascade. Shows no PLC activity to phosphatidylinositol 4,5-bisphosphate and phosphatidylinositol.
Synonyms: Phospholipase C-deleted in lung carcinomaMirtazapine
go.drugbank.com/drugs/DB00370ApprovedInvestigational[A178144,L6160] In addition to its beneficial effects in depression, mirtazapine has been reported to be efficacious in the off-label management of various other conditions. … Mirtazapine is a tetracyclic _piperazino-azepine_ antidepressant agent that was initially approved for the treatment of major depressive disorder (MDD) in the Netherlands in 1994.
Products: REMERON IV, MİTAZEN 15 MG/5 ML IV İNFÜZYON İÇİN KONSANTRE ÇÖZELTİ İÇEREN AMPUL, 12 AMPULGremlin-1
go.drugbank.com/bio_entities/BE0011799TargetHumansDown-regulates the BMP4 signaling in a dose-dependent manner (By similarity). Antagonist of BMP2; inhibits BMP2-mediated differentiation of osteoblasts (in vitro) (PubMed:27036124). … Cytokine that may play an important role during carcinogenesis and metanephric kidney organogenesis, as a BMP antagonist required for early limb outgrowth and patterning in maintaining the FGF4-SHH feedback
Synonyms: Increased in high glucose protein 2, Down-regulated in Mos-transformed cells proteinGlabellar Frown Lines (GL)
go.drugbank.com/conditions/DBCOND0081153Drugs: Botulinum toxin type ASynonyms: Glabellar Lines, Glabellar Frown LinesSplinter
go.drugbank.com/conditions/DBCOND0015551Drugs: IchthammolSynonyms: Splinter in skin (disorder)Dextromethorphan
go.drugbank.com/drugs/DB00514ApprovedInvestigational[A215412] Although similar in structure to other opioids, it has minimal interaction with opioid receptors.[A215412] Dextromethorphan was granted FDA approval before 3 December 1957. … Dextromethorphan is a levorphanol derivative and codeine analog commonly used as a cough suppressant and also a drug of abuse.
Mixtures: Cold & Flu-IN-one, Cold and Flu All In OneCategories: Uncompetitive N-methyl-D-aspartate Receptor AntagonistCytoplasmic tyrosine-protein kinase BMX
go.drugbank.com/bio_entities/BE0009416TargetHumansMay also play a role in the growth and differentiation of hematopoietic cells; as well as in signal transduction in endocardial and arterial endothelial cells … Plays a critical role in TNF-induced angiogenesis, and implicated in the signaling of TEK and FLT1 receptors, 2 important receptor families essential for angiogenesis.
Synonyms: Bone marrow tyrosine kinase gene in chromosome X proteinCobimetinib
go.drugbank.com/drugs/DB05239ApprovedInvestigationalIt has been approved in Switzerland and the US, in combination with vemurafenib for the treatment of patients with unresectable or metastatic BRAF V600 mutation-positive melanoma. … Cobimetinib is an orally active, potent and highly selective small molecule inhibiting mitogen-activated protein kinase kinase 1 (MAP2K1 or MEK1), and central components of the RAS/RAF/MEK/ERK signal transduction
Hypochlorous acid
go.drugbank.com/drugs/DB14135InvestigationalAn oxyacid of chlorine (HClO) containing monovalent chlorine that acts as an oxidizing or reducing agent.
Categories: Compounds used in a research, industrial, or household settingSynonyms: Chlor(I)-säureZiprasidone
go.drugbank.com/drugs/DB00246ApprovedInvestigational[A180748] It can effectively reduce the rate and time of relapses in schizophrenia, and can be used to treat manic episodes in bipolar disorder although the mechanism of action is unknown. … [A180748] Although ziprasidone is classified as an atypical antipsychotic, it appears to have a lower incidence of metabolic adverse effects compared to other medications in the same class.[A190525]
Products: ZELDOX IM ENJ. SOL. ICIN KURU TOZ ICEREN FLAKON 20MG/ML FLAKON, 1 ADET