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Melanoma
go.drugbank.com/conditions/DBCOND0020306Synonyms: Malignant melanoma, no ICD-O subtype, Malignant melanoma, no International Classification of Diseases for Oncology subtypeIsocarboxazid
go.drugbank.com/drugs/DB01247Approved[T115] It was first introduced by Roche pharmaceuticals, further developed by Validus pharms Inc and first FDA approved as a prescription drug on July 1st, 1959. … Isocarboxazid has the formula 1-benzyl-2-(5-methyl-3-isoxazolylcarbonyl)hydrazine-isocarboxazid. It is a monoamine oxidase inhibitor.
Categories: Monoamine Oxidase Inhibitors, Non-Selective, Monoamine Oxidase A Inhibitors for interaction with Monoamine Oxidase A substratesSulisobenzone
go.drugbank.com/drugs/DB11185ApprovedSulisobenzone is approved by the FDA in concentrations of up to 10% and in Canada, is approved by Health Canada at the same concentrations [F38]. … It works to filter out both UVA and UVB rays, protecting the skin from sun UV damage [L2153].
Salts: Benzophenone-5Mixtures: Givenchy Radically No Surgetics, Nioxin Scalp Treatment System 6 SPF 15 Sunscreen - Medium to Coarse HairProteasome subunit beta type-2
go.drugbank.com/bio_entities/BE0002349TargetHumansThis type of proteolysis is required in several pathways including spermatogenesis (20S-PA200 complex) or generation of a subset of MHC class I-presented antigenic peptides (20S-PA28 complex) … 26S proteasome plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins that could impair cellular functions, and by removing proteins whose functions are no
Synonyms: Macropain subunit C7-I, Proteasome component C7-ITranscobalamin-1
go.drugbank.com/bio_entities/BE0000238TargetTransporterCarrierHumansBinds vitamin B12 with femtomolar affinity and protects it from the acidic environment of the stomach
Synonyms: TC I, Transcobalamin ICalcitonin gene-related peptide 1
go.drugbank.com/bio_entities/BE0001103TargetHumansCGRP1 can also bind and activate CALCR-RAMP1 (AMYR1) receptor complex (PubMed:38603770)
Synonyms: CGRP-I, Calcitonin gene-related peptide IDNA topoisomerase 1
go.drugbank.com/bio_entities/BE0000971TargetEnzymeHumansReleases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification a...
Synonyms: DNA topoisomerase IMepivacaine
go.drugbank.com/drugs/DB00961ApprovedInvestigationalVet approvedA local anesthetic that is chemically related to bupivacaine but pharmacologically related to lidocaine. It is indicated for infiltration, nerve block, and epidural anesthesia. … Mepivacaine is effective topically only in large doses and therefore should not be used by this route. (From AMA Drug Evaluations, 1994, p168)
Mixtures: Carbocaine 2% With Neo-cobefrin, Carbocaine 2% With Neo-cobefrinCategories: Heterocyclic Compounds, 1-RingOpium
go.drugbank.com/drugs/DB11130ApprovedIllicitDuring the years, opium was used as a sedative and hypnotic, but it was determined to be addictive.[A32171] Opium is extracted from _Papaver somniferum_, which is more known as poppies. … This plant is an integrant of the Papaveraceae family, and it is characterized by solitary leaves and capsulated fruits.
Mixtures: Diban Cap, Diban CapCategories: Serotonergic Drugs Shown to Increase Risk of Serotonin Syndrome, Cytochrome P-450 SubstratesOmega-3-acid ethyl esters
go.drugbank.com/drugs/DB09539ApprovedInvestigationalOmega-3-acid ethyl esters are prescription drugs that contain eicosapentaenoic acid-ethyl ester (EPA) and docosahexaenoic acid-ethyl ester (DHA) that are used in combination with changes in diet to lower … Omega-3-acid ethyl esters are currently marketed in the US, EU, and many other regions under the brand name Lovaza[FDA Label][L5849].
Synonyms: omega-3 acid ethyl esters, Omega-3-acid ethyl estersMixtures: Mi-Omega NF, ROSUVASTATINA E OMEGA 3 SPA SOCIET PRODOTTI ANTIBIOTICI