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Eplerenone
go.drugbank.com/drugs/DB00700ApprovedInvestigationalEplerenone, an aldosterone receptor antagonist similar to spironolactone, has been shown to produce sustained increases in plasma renin and serum aldosterone, consistent with inhibition of the negative … regulatory feedback of aldosterone on renin secretion.
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A SubstratesProducts: EPLERENON AL 25MG FTA, EPLERENON AL 50MG FTAPotassium voltage-gated channel subfamily A member 1
go.drugbank.com/bio_entities/BE0000781TargetHumansRegulates the frequency of neuronal action potential firing in response to mechanical stimuli, and plays a role in the perception of pain caused by mechanical stimuli, but does not play a role in the perception … In contrast, a heterotetrameric channel formed by KCNA1 and KCNA4 shows rapid inactivation (PubMed:17156368).
Polypeptides: Potassium voltage-gated channel subfamily A member 1HLA class I histocompatibility antigen, A alpha chain
go.drugbank.com/bio_entities/BE0003483TargetHumansIn complex with B2M/beta 2 microglobulin displays primarily viral and tumor-derived peptides on antigen-presenting cells for recognition by alpha-beta T cell receptor (TCR) on HLA-A-restricted CD8-positive
Polypeptides: HLA class I histocompatibility antigen, A alpha chainSynonyms: HLA-A, MHC class I antigen A*3Potassium voltage-gated channel subfamily A member 7
go.drugbank.com/bio_entities/BE0004719TargetHumansAssuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a potassium-selective channel through which potassium ions may pass in accordance with
Polypeptides: Potassium voltage-gated channel subfamily A member 7C-type lectin domain family 14 member A
go.drugbank.com/bio_entities/BE0005467TargetHumansPolypeptides: C-type lectin domain family 14 member ASynonyms: Epidermal growth factor receptor 5C-type lectin domain family 10 member A
go.drugbank.com/bio_entities/BE0016623TargetHumansActs as a signaling receptor at the interface of APC-T cell interactions. … Binds in a Ca(2+)-dependent manner to alpha- and beta-linked GalNAc residues on glycoprotein and glycolipid antigens, including alphaGalNAc- and Galbeta1->3GalNAc-O-Ser/Thr also known as Tn and T antigens
Polypeptides: C-type lectin domain family 10 member ASynonyms: DC-asialoglycoprotein receptorC-type lectin domain family 7 member A
go.drugbank.com/bio_entities/BE0019143TargetHumansLectin that functions as a pattern recognizing receptor (PRR) specific for beta-1,3-linked and beta-1,6-linked glucans, which constitute cell wall constituents from pathogenic bacteria and fungi (PubMed … Binds T-cells in a way that does not involve their surface glycans and plays a role in T-cell activation. Stimulates T-cell proliferation.
Polypeptides: C-type lectin domain family 7 member ASynonyms: Beta-glucan receptorDextran
go.drugbank.com/drugs/DB09255ApprovedInvestigationalVet approvedDextran 75 is a complex branched glucan with an average molecular weight 75000 Daltons. … Dextran is a polysaccharide that differs from others in that its glucose units are joined together 1:6 glucoside links.
Mixtures: Best Choice Eye Drops Advanced Relief, Dextran 6% In 5% Dextrose InjectionCategories: Compounds used in a research, industrial, or household settingNitrogen
go.drugbank.com/drugs/DB09152ApprovedInvestigationalVet approvedNitrogen is a chemical element with symbol N and atomic number 7. At room temperature, it is a transparent, odorless diatomic gas.
Mixtures: Oxygen W Nitrogen, OXIMED CLINAPAL®Products: N/APralidoxime
go.drugbank.com/drugs/DB00733ApprovedInvestigationalVet approvedPralidoxime is an antidote to organophosphate pesticides and chemicals.
Categories: Compounds used in a research, industrial, or household settingSynonyms: 2-PAM