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Carbocisteine
go.drugbank.com/drugs/DB04339ApprovedInvestigational[A230993] Carbocisteine is currently not FDA or Health Canada approved, but is approved for use in Asia, Europe, and South America. … Carbocisteine is a mucolytic drug that alleviates respiratory symptoms and infections by reducing the viscosity of mucus, allowing it to be expelled.
Synonyms: (L)-2-Amino-3-(carboxymethylthio)propionic acid, (R)-S-(carboxymethyl)cysteineMixtures: TUSSYL® MIEL JARABE, AXIM TOSTHERAPY FORTE®Protein-arginine deiminase type-1
go.drugbank.com/bio_entities/BE0002314TargetHumansCatalyzes the deimination of arginine residues of proteins
Synonyms: Peptidylarginine deiminase I, Protein-arginine deiminase type ILymphoma, Diffuse
go.drugbank.com/conditions/DBCOND0036855Synonyms: Non-Hodgkin lymphoma, no ICD-O subtype, Non-Hodgkin lymphoma, no ICD-O subtype (morphologic abnormality)Testosterone enanthate
go.drugbank.com/drugs/DB13944ApprovedInvestigationalThe majority of the prescriptions written were for injectable (66%) and topical (32%) testosterone products. As recent as 1 October 2018, the US FDA approved Antares Pharma Inc.' … This slow release is achieved by the presence of the enanthate ester functional group attached to the testosterone molecule.
Mixtures: Neo Pause Injection, NOFERTYL® INYECTABLECategories: P-glycoprotein inhibitors, Cytochrome P-450 SubstratesCholesteryl ester transfer protein
go.drugbank.com/bio_entities/BE0003516TargetHumansInvolved in the transfer of neutral lipids, including cholesteryl ester and triglyceride, among lipoprotein particles. Allows the net movement of cholesteryl ester from high density lipoproteins/HDL to triglyceride-rich very low density ...
Synonyms: Lipid transfer protein INoncanonical Wnt/Ca2+ signaling
smpdb.ca/view/SMP0468891SignalingThe Wnt/Ca²⁺ pathway is activated by the binding of the Wnt ligand to a Frizzled receptor.
3-dehydroquinate dehydratase
go.drugbank.com/bio_entities/BE0001819TargetSalmonella typhiInvolved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids. Catalyzes the cis-dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3-d...
Synonyms: Type I DHQase, Type I dehydroquinaseOctasulfur
go.drugbank.com/drugs/DB09353ApprovedSulfur seems to have an antibacterial activity. It has been also used for acne. … People take sulfur by mouth for shortness of breath, allergies, swelling in the back of the throat (pharyngitis), high cholesterol, clogged arteries, menopause, and upper respiratory tract infections like
Mixtures: POLY-N OINTMENT, NW SULPHUR 2%W/W AND SALICYLIC ACID 2%W/W CREAMProducts: Liquimat Acne Treatment and Cover-UP, Sulfo loEdoxudine
go.drugbank.com/drugs/DB13421ApprovedWithdrawnIt was later recognized to be effective in vivo in a preclinical model of keratitis caused by herpes virus. … [A32643] It was developed by McNeil Pharmaceutical and approved by Health Canada on December 31, 1992. This medication was later discontinued from the market in 1998.[L1113]
Synonyms: 2'-Deoxy-5-ethyluridine, 5-Ethyl-2'-deoxyuridineCategories: Heterocyclic Compounds, 1-RingAlendronic acid
go.drugbank.com/drugs/DB00630ApprovedInvestigationalIt functions by preventing resorption of bone[FDA Label][A959]. … Alendronic acid is a second generation bisphosphonate that is used for the treatment of some forms of osteoperosis and Paget's disease[FDA Label][A959,A203111].
Synonyms: (4-amino-1-hydroxybutylidene)bisphosphonic acid, 4-amino-1-hydroxybutane-1,1-diphosphonic acidMixtures: ALENDRON-HEXAL 4 WO CAL D, ALENDRON-HEXAL 12 WO CAL D