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Displaying results 941 - 950 of 10000 in total
  1. Indication

    Severe Glabellar Frown Lines (GL)

    go.drugbank.com/conditions/DBCOND0146865
    Drugs: Botulinum toxin type A · DaxibotulinumtoxinA
    Synonyms: Severe Glabellar Frown Lines (GL)
  2. Drug

    Eplerenone

    go.drugbank.com/drugs/DB00700
    ApprovedInvestigational

    Eplerenone, an aldosterone receptor antagonist similar to spironolactone, has been shown to produce sustained increases in plasma renin and serum aldosterone, consistent with inhibition of the negative … regulatory feedback of aldosterone on renin secretion.

    Products: INSPRA IC
  3. Drug

    Tryptophan

    go.drugbank.com/drugs/DB00150
    ApprovedInvestigationalNutraceuticalWithdrawn

    An essential amino acid that is necessary for normal growth in infants and for nitrogen balance in adults. It is a precursor of indole alkaloids in plants. … It is a precursor of serotonin (hence its use as an antidepressant and sleep aid). It can be a precursor to niacin, albeit inefficiently, in mammals.

    Mixtures: Aminosyn II in Dextrose, Aminosyn II in Dextrose
  4. Target

    DNA damage-inducible transcript 4 protein

    go.drugbank.com/bio_entities/BE0003445
    TargetHumans

    Its role in the response to hypoxia depends on the cell type; it mediates mTORC1 inhibition in fibroblasts and thymocytes, but not in hepatocytes (By similarity). … Plays a role in neuronal cell death

    Synonyms: Protein regulated in development and DNA damage response 1
  5. Drug

    Sugemalimab

    go.drugbank.com/drugs/DB16641
    ApprovedInvestigational

    [L53333] In combination with platinum-based chemotherapy, sugemalimab is a first-line treatment indicated for adult populations with metastatic non-small cell lung cancer (NSCLC) with no sensitising EGFR … [L32868, L32873, L53333] The antibody is produced in Chinese hamster ovary cells by recombinant DNA technology.

  6. Drug

    Dipotassium phosphate

    go.drugbank.com/drugs/DB09414
    ApprovedInvestigational

    Dipotassium phosphate (K2HPO4) is a highly water-soluble salt often used as a fertilizer and food additive as a source of phosphorus and potassium as well as a buffering agent.

    Mixtures: Isolyte M in Dextrose, Isolyte P in DextroseCategories: Compounds used in a research, industrial, or household setting
  7. Drug

    Phenylalanine

    go.drugbank.com/drugs/DB00120
    ApprovedInvestigationalNutraceutical

    Phenylalanine is an essential aromatic amino acid that is a precursor of melanin, [dopamine], [noradrenalin] (norepinephrine), and [thyroxine].

    Mixtures: Aminosyn II in Dextrose, Aminosyn II in Dextrose
  8. Target

    Nuclear factor NF-kappa-B p105 subunit

    go.drugbank.com/bio_entities/BE0001086
    TargetHumans

    NF-kappa-B complexes are held in the cytoplasm in an inactive state complexed with members of the NF-kappa-B inhibitor (I-kappa-B) family. … the enhancer region of genes involved in immune response and acute phase reactions.

    Synonyms: Nuclear factor of kappa light polypeptide gene enhancer in B-cells 1
  9. Drug

    Isoleucine

    go.drugbank.com/drugs/DB00167
    ApprovedInvestigationalNutraceutical

    An essential branched-chain aliphatic amino acid found in many proteins. It is an isomer of leucine. It is important in hemoglobin synthesis and regulation of blood sugar and energy levels.

    Mixtures: Aminosyn II in Dextrose, Aminosyn II in Dextrose
  10. Drug

    Histidine

    go.drugbank.com/drugs/DB00117
    ApprovedInvestigationalNutraceutical

    An essential amino acid that is required for the production of histamine.

    Mixtures: Aminosyn II in Dextrose, Aminosyn II in Dextrose