Search

Displaying results 9501 - 9510 of 10000 in total
  1. Target

    1-phosphatidylinositol phosphodiesterase

    go.drugbank.com/bio_entities/BE0001955
    TargetBacillus cereus

    Cleaves glycosylphosphatidylinositol (GPI) and phosphatidylinositol (PI) anchors but not PI phosphates.

    Polypeptides: 1-phosphatidylinositol phosphodiesterase
  2. Target

    Neuroendocrine convertase 1

    go.drugbank.com/bio_entities/BE0002125
    EnzymeHumans

    Involved in the processing of hormone and other protein precursors at sites comprised of pairs of basic amino acid residues. Substrates include POMC, renin, oxytocin, vasopressin, enkephalin, dynorphin, somatostatin, insulin and AGRP

    Polypeptides: Neuroendocrine convertase 1Synonyms: NEC 1, Prohormone convertase 1
  3. Target

    Succinate receptor 1

    go.drugbank.com/bio_entities/BE0002258
    TargetHumans

    G protein-coupled receptor for succinate able to mediate signaling through Gq/GNAQ or Gi/GNAI second messengers depending on the cell type and the processes regulated (By similarity) (PubMed:15141213, PubMed:23770096, PubMed:34133934). S...

    Polypeptides: Succinate receptor 1Synonyms: P2Y purinoceptor 1-like
  4. Target

    Histone deacetylase 1

    go.drugbank.com/bio_entities/BE0002365
    TargetHumans

    Histone deacetylase that catalyzes the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4) (PubMed:16762839, PubMed:17704056, PubMed:28497810). Histone deacetylation gives a tag for epigenet...

    Polypeptides: Histone deacetylase 1
  5. Target

    Uridine phosphorylase 1

    go.drugbank.com/bio_entities/BE0002456
    EnzymeTargetHumans

    Catalyzes the reversible phosphorylytic cleavage of uridine to uracil and ribose-1-phosphate which can then be utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide

    Polypeptides: Uridine phosphorylase 1Synonyms: UPase 1, UrdPase 1
  6. Target

    Glutamine synthetase 1

    go.drugbank.com/bio_entities/BE0002555
    TargetMycobacterium tuberculosis

    Involved in nitrogen metabolism via ammonium assimilation. Catalyzes the ATP-dependent biosynthesis of glutamine from glutamate and ammonia (PubMed:12819079, PubMed:7937767). Also able to use GTP (PubMed:7937767). D-glutamate is a poor s...

  7. Target

    Liver carboxylesterase 1

    go.drugbank.com/bio_entities/BE0002705
    TargetEnzymeHumans

    Involved in the detoxification of xenobiotics and in the activation of ester and amide prodrugs (PubMed:18762277, PubMed:7980644, PubMed:9169443, PubMed:9490062). Hydrolyzes aromatic and aliphatic esters, but has no catalytic activity to...

    Polypeptides: Liver carboxylesterase 1Synonyms: CE-1, hCE-1
  8. Target

    Aldose 1-epimerase

    go.drugbank.com/bio_entities/BE0002844
    TargetLactococcus lactis

    Polypeptides: Aldose 1-epimeraseFunction: aldose 1-epimerase activity
  9. Target

    HIV-1 retropepsin

    go.drugbank.com/bio_entities/BE0003328
    TargetHuman immunodeficiency virus 1

    Polypeptides: HIV-1 retropepsinSynonyms: V-1 protease
  10. Target

    Steroidogenic factor 1

    go.drugbank.com/bio_entities/BE0003359
    TargetHumans

    Also regulates the AMH/Muellerian inhibiting substance gene as well as the AHCH and STAR genes. 5'-YCAAGGYC-3' and 5'-RRAGGTCA-3' are the consensus sequences for the recognition by NR5A1 (PubMed:27378692

    Polypeptides: Steroidogenic factor 1Synonyms: Nuclear receptor subfamily 5 group A member 1, hSF-1