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Technetium Tc-99m nofetumomab merpentan
go.drugbank.com/drugs/DB09336ApprovedWithdrawnIt was after discontinued on August 13, 2013, but in the 2018 FDA submission list, it can be found as a substance type II (Drug substance) with an active status.[L1650, L1082] … [FDA label] Tc-99m nm was developed by Boehringer Ingelheim Pharma KG and FDA approved on September 14, 1992.
Montelukast
go.drugbank.com/drugs/DB00471ApprovedInvestigationalMontelukast was first approved for clinical use by the US FDA in 1998 as Merck's brand name Singulair. … worldwide via millions of prescriptions annually and has since become available as a generic and as a brand name product.
Synonyms: (R-(E))-1-(((1-(3-(2-(7-Chloro-2-quinolinyl)ethenyl)phenyl)-3-(2-(1-hydroxy-1-methylethyl)phenyl)propyl)thio)methyl)cyclopropaneacetic acid, 1-[[[(1 R)-1-[3-[(1E)-2-(7-chloro-2-quinolinyl)ethenyl] phenyl]-3-[2-(1-hydroxy-1-methylethyl)phenyl]propyl]sulfanyl]methyl]cyclopropaneacetic acidMixtures: BROCRIPTIN® 10 MG/ 5 MG, GLEMONT L® TABLETAS RECUBIERTASMepyramine
go.drugbank.com/drugs/DB06691ApprovedVet approvedIt has been found in over-the-counter combination products for colds and menstrual symptoms, but is considered to be an unapproved prescription medication used for cough, cold, or allergic conditions. … It is a first generation antihistamine. However, it rapidly permeates the brain and so often causes drowsiness as a side effect.
Mixtures: I D M Expectorant Tab, K-FENIDEX JEL 30 GCategories: Heterocyclic Compounds, 1-Ring, Cytochrome P-450 CYP2D6 InhibitorsSodium acetate
go.drugbank.com/drugs/DB09395ApprovedInvestigationalIt can be used also in metabolic acidosis and for urine alkalinization. … Medically, sodium acetate is important component as an electrolyte replenisher when given intravenously. It is mainly indicated to correct sodium levels in hyponatremic patients.
Mixtures: INYECCION MULTIPLE DE ELECTROLITOS TIPO I, OLICLINOMEL N4-550 E EMULSION FOR INFUSIONSynonyms: Acetic acid, sodium salt (1:1)Lactoylglutathione lyase
go.drugbank.com/bio_entities/BE0000962TargetEnzymeHumansCatalyzes the conversion of hemimercaptal, formed from methylglyoxal and glutathione, to S-lactoylglutathione (PubMed:20454679, PubMed:23122816, PubMed:9705294). Involved in the regulation of TNF-induced transcriptional activity of NF-ka...
Synonyms: Glx I, Glyoxalase IPeptidoglycan recognition protein 3
go.drugbank.com/bio_entities/BE0003077TargetHumansPattern receptor that binds to murein peptidoglycans (PGN) of Gram-positive bacteria. Has bactericidal activity towards Gram-positive bacteria. May kill Gram-positive bacteria by interfering with peptidoglycan biosynthesis. Also binds to...
Synonyms: PGRP-I-alpha, Peptidoglycan recognition protein I-alphaUblituximab
go.drugbank.com/drugs/DB11850ApprovedInvestigational[A244210, A244215,A241045] Ublituximab was initially developed by LFB Group but was licensed to TG Therapeutics in 2012. … CD20, an antigen expressed by various B and T cells, is an attractive therapeutic target in various cancers and autoimmune conditions.
Categories: Leukemia, Lymphocytic, Chronic, B-Cell, drug therapyCalcium chloride
go.drugbank.com/drugs/DB01164ApprovedInvestigationalIt can be produced directly from limestone, but large amounts are also produced as a by-product of the Solvay process. Because of its hygroscopic nature, it must be kept in tightly-sealed containers. … It has several common applications such as brine for refrigeration plants, ice and dust control on roads, and in cement.
Synonyms: calcium(2+) chlorideInternational brands: LiquiCal-D 400Strontium ranelate
go.drugbank.com/drugs/DB09267ApprovedWithdrawnAvailable for prescription use for a time in some parts of the world as Protelos (strontium ranelate) 2 g granules for oral suspension by Servier, it was ultimately discontinued in 2016-2017 owing to an … This agent presents an atypical mechanism of action in which it increases deposition of new bone by osteoblasts and, simultaneously, reduces the resorption of bone by osteoclasts.
Mixtures: FULLBONE D3 2 G/800 IU EFERVESAN TABLET, 30 ADET, FULLBONE D3 2 G/800 IU EFERVESAN TABLET, 60 ADETCategories: Heterocyclic Compounds, 1-RingLosartan
go.drugbank.com/drugs/DB00678ApprovedInvestigational[L7423] Angiotensin-converting enzyme (ACE) inhibitors are used for a similar indication but are associated with a cough. … Losartan is an angiotensin II receptor blocker (ARB) used to treat hypertension.
Synonyms: 2-n-butyl-4-chloro-5-hydroxymethyl-1-[(2'-(1H-tetrazol-5-yl)biphenyl-4-yl)methyl]imidazole, (2-butyl-4-chloro-1-{[2'-(1H-tetrazol-5-yl)biphenyl-4-yl]methyl}-1H-imidazol-5-yl)methanolMixtures: Van-losartan-hctz, Van-losartan-hctz