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Displaying results 951 - 960 of 8696 in total
  1. Drug

    Phenylalanine

    go.drugbank.com/drugs/DB00120
    ApprovedInvestigationalNutraceutical

    Phenylalanine is an essential aromatic amino acid that is a precursor of melanin, [dopamine], [noradrenalin] (norepinephrine), and [thyroxine].

    Mixtures: Aminosyn-PF, Aminosyn-PF
  2. Pathway

    Intracellular Signalling Through Prostacyclin Receptor and Prostacyclin

    smpdb.ca/view/SMP0000354
    Signaling

    The receptor is a G-protein coupled receptor, upon its binding it activates G proteins causing the activation of adenylyl cyclase and production of cAMP messenger molecules. cAMP activates PKA (protein … Prostacyclin binding to its receptor increases vasodilation and decreases platelet aggregation.

    Drugs: ATP · Calcium · Magnesium cation · Cyclic adenosine monophosphate · Pyrophosphoric acid
    Enzymes: Prostacyclin receptor
  3. Pathway

    Trimebutine M3 Receptor Intestine Relaxation Action Pathway

    smpdb.ca/view/SMP0126338
    Drug action

    Possible side effects of using trimebutine may include dry mouth, heartburn, nausea, and drowsiness.

    Drugs: ATP · Nitric Oxide · Potassium cation · Calcium · Magnesium cation · Cyclic adenosine monophosphate +3 more
    Enzymes: Mu-type opioid receptor, Muscarinic acetylcholine receptor M3
  4. Drug

    Amubarvimab

    go.drugbank.com/drugs/DB16493
    Investigational

    Amubarvimab (BRII-196) was under investigation in clinical trials (NCT04691180 and NCT04787211) to treat COVID-19, focusing on its safety, tolerability, and efficacy.

    Synonyms: IMMUNOGLOBULIN G1-KAPPA, ANTI-(SEVERE ACUTE RESPIRATORY SYNDROME CORONAVIRUS 2 (SARS-COV-2) SPIKE (S) GLYCOPROTEIN, RECEPTOR BINDING DOMAIN (RBD)), HOMO SAPIENS MONOCLONAL ANTIBODYCategories: Experimental Unapproved Treatments for COVID-19
  5. Drug

    Imidapril

    go.drugbank.com/drugs/DB11783
    Investigational

    Imidapril has been investigated for the treatment of Kidney, Polycystic, Autosomal Dominant.

    Products: PRILIUM 150MG POWDER FOR ORAL SOLUTION
  6. Indication

    Transient Ischemic Attack

    go.drugbank.com/conditions/DBCOND0029275
    Drugs: Acenocoumarol · Acetylsalicylic acid · Atorvastatin · Dipyridamole · Glycine · Nicergoline +2 more
  7. Drug

    Flutemetamol

    go.drugbank.com/drugs/DB15058
    Investigational

    Flutemetamol is under investigation in clinical trial NCT02353949 (Investigating the Clinical Consequences of Flutemetamol-PET-scanning).

    Products: VIZAMYL SOLUTION FOR INJECTION 150 MBq/mL
  8. Drug

    Anvatabart opadotin

    go.drugbank.com/drugs/DB18290
    Investigational

    Synonyms: Arx-788 (anti-her2 mab paf- mmaf toxin oxime conjugate), Immunoglobulin G1-kappa, anti-[Homo sapiens ERBB2 (epidermal growth factor receptor 2, receptor tyrosine-protein kinase erbB-2, EGFR2, HER2, HER-2, p185c-erbB2, NEU, CD340)], humanized monoclonal antibody
  9. Drug

    Venlafaxine

    go.drugbank.com/drugs/DB00285
    ApprovedInvestigational

    [A252065] Venlafaxine has been used as a first-line treatment for MDD, GAD, social anxiety disorder, and panic disorder in Canada for many years. … Venlafaxine is an antidepressant and a serotonin and norepinephrine reuptake inhibitor (SNRI).

    Categories: Antidepressive Agents Indicated for Depression, P-glycoprotein inhibitorsProducts: Mar-venlafaxine XR
  10. Drug

    Pantothenic acid

    go.drugbank.com/drugs/DB01783
    ApprovedInvestigationalNutraceuticalVet approved

    For many animals, pantothenic acid is an essential nutrient as it is required to synthesize coenzyme-A (CoA), as well as to synthesize and metabolize proteins, carbohydrates, and fats. … Only the dextrorotatory (D) isomer of pantothenic acid possesses biological activity. while the levorotatory (L) form may antagonize the effects of the dextrorotatory isomer.

    Mixtures: Doctor's Choice Brand for Men, Ultra HrCategories: Preparations for Treatment of Wounds and Ulcers