Search

Displaying results 971 - 980 of 3735 in total
  1. Target

    Neuronal acetylcholine receptor subunit alpha-5

    go.drugbank.com/bio_entities/BE0003586
    TargetHumans

    Increases receptor sensitivity to acetylcholine and nicotine when associated with CHRNA4 and CHRNB2 (PubMed:8663494). Plays a role in nicotine addiction (PubMed:20881005)

    Polypeptides: Neuronal acetylcholine receptor subunit alpha-5Function: acetylcholine receptor activity
  2. Target

    Gamma-aminobutyric acid receptor subunit pi

    go.drugbank.com/bio_entities/BE0003596
    TargetHumans

    In the lungs, pi-containing GABAARs contribute to pulmonary fluid transport via luminal secretion of chloride (By similarity)

    Polypeptides: Gamma-aminobutyric acid receptor subunit piSynonyms: GABA(A) receptor subunit pi
  3. Target

    T cell receptor alpha chain constant

    go.drugbank.com/bio_entities/BE0003778
    TargetHumans

    Constant region of T cell receptor (TR) alpha chain (PubMed:24600447).

    Polypeptides: T cell receptor alpha chain constant
  4. Target

    Hepatitis B virus receptor binding protein

    go.drugbank.com/bio_entities/BE0004339
    TargetHumans

    Polypeptides: Hepatitis B virus receptor binding protein
  5. Target

    Non-receptor tyrosine-protein kinase TNK1

    go.drugbank.com/bio_entities/BE0009400
    TargetHumans

    Involved in negative regulation of cell growth. Has tumor suppressor properties. Plays a negative regulatory role in the Ras-MAPK pathway. May function in signaling pathways utilized broadly during fetal development and more selectively ...

    Polypeptides: Non-receptor tyrosine-protein kinase TNK1
  6. Target

    Muscle, skeletal receptor tyrosine-protein kinase

    go.drugbank.com/bio_entities/BE0009491
    TargetHumans

    May also play a role in acetylcholinesterase (AChE) localization at the neuromuscular junctions (NMJ) via its interaction wit COLQ (By similarity). … Receptor tyrosine kinase which plays a central role in the formation and the maintenance of the neuromuscular junction (NMJ), the synapse between the motor neuron and the skeletal muscle (PubMed:25537362

    Polypeptides: Muscle, skeletal receptor tyrosine-protein kinaseSynonyms: Muscle-specific kinase receptor, Muscle-specific tyrosine-protein kinase receptor
  7. Target

    IgG receptor FcRn large subunit p51

    go.drugbank.com/bio_entities/BE0010182
    TargetTransporterCarrierHumans

    Cell surface receptor that transfers passive humoral immunity from the mother to the newborn.

    Polypeptides: IgG receptor FcRn large subunit p51Synonyms: Neonatal Fc receptor, IgG Fc fragment receptor transporter alpha chain
  8. Target

    Receptor-type tyrosine-protein phosphatase C

    go.drugbank.com/bio_entities/BE0010406
    TargetHumans

    Protein tyrosine-protein phosphatase required for T-cell activation through the antigen receptor (PubMed:35767951). Acts as a positive regulator of T-cell coactivation upon binding to DPP4. … Interacts with CLEC10A at antigen presenting cell-T cell contact; CLEC10A on immature dendritic cells recognizes Tn antigen-carrying PTPRC/CD45 receptor on effector T cells and modulates T cell activation

    Polypeptides: Receptor-type tyrosine-protein phosphatase C
  9. Target

    Killer cell immunoglobulin-like receptor 2DL1

    go.drugbank.com/bio_entities/BE0010669
    TargetHumans

    Receptor on natural killer (NK) cells for some HLA-C alleles such as w4 and w6. Inhibits the activity of NK cells thus preventing cell lysis

    Polypeptides: Killer cell immunoglobulin-like receptor 2DL1Synonyms: p58 NK receptor CL-42/47.11, p58.1 MHC class-I-specific NK receptor
  10. Target

    Baculoviral IAP repeat-containing protein 1

    go.drugbank.com/bio_entities/BE0010810
    TargetHumans

    Anti-apoptotic protein which acts by inhibiting the activities of CASP3, CASP7 and CASP9. Can inhibit the autocleavage of pro-CASP9 and cleavage of pro-CASP3 by CASP9. Capable of inhibiting CASP9 autoproteolysis at 'Asp-315' and decreasi...

    Polypeptides: Baculoviral IAP repeat-containing protein 1