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Dantron
go.drugbank.com/drugs/DB04816ApprovedWithdrawnWithdrawn from the Canadian, US, and UK markets in 1998 due to genotoxicity.
International brands: Scatron DMixtures: Regulex D CapPyruvate dehydrogenase E1 component subunit alpha, somatic form, mitochondrial
go.drugbank.com/bio_entities/BE0000571TargetEnzymeHumansTogether with PDHB forms the heterotetrameric E1 subunit of the pyruvate dehydrogenase (PDH) complex (PubMed:17474719, PubMed:19081061). The PDH complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2), and thereby li...
Synonyms: PDHE1-A type ILoteprednol etabonate
go.drugbank.com/drugs/DB14596ApprovedAs a nasal spray, it can be used for the treatment and management of seasonal allergic rhinitis. … Most prescription LE products, however, tend to be indicated for the treatment of post-operative inflammation and pain following ocular surgery [FDA Label].
Mixtures: TOBRALOT 5 MG+3 MG/ML GÖZ DAMLASI, SÜSPANSİYON, 1 ADET, LOTEMICIN®Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A SubstratesEctonucleotide pyrophosphatase/phosphodiesterase family member 3
go.drugbank.com/bio_entities/BE0011403TargetHumansAlso hydrolyzes extracellular 2',3'-cGAMP (cyclic GMP-AMP), a second messenger that activates TMEM173/STING and triggers type-I interferon production, and is therefore involved in the regulation of innate … Can hydrolyze extracellular dinucleoside polyphosphates, including the vasoactive adenosine polyphosphates as well (PubMed:12846830).
Synonyms: Alkaline phosphodiesterase I, Phosphodiesterase I betaDesloratadine
go.drugbank.com/drugs/DB00967ApprovedInvestigationalDesloratidine has a long-lasting effect and does not cause drowsiness because it does not readily enter the central nervous system. … It is the active descarboethoxy metabolite of loratidine (a second generation histamine).
Synonyms: 8-Chloro-11-piperidin-4-ylidene-6,11-dihydro-5H-benzo[5,6]cyclohepta[1,2-b]pyridine, 8-chloro-6,11-dihydro-11-(4-piperidinylidene)-5H-benzo(5,6)cyclohepta(1,2-b)pyridineMixtures: NEUMOLEX® NF, BUCOXOL ® GRIP MAX CAPSULAS DURAS CON CONTENIDO LIQUIDORespiratory syncytial virus vaccine, adjuvanted
go.drugbank.com/drugs/DB17762ApprovedInvestigationalArexvy (respiratory syncytial virus vaccine, adjuvanted) is an adjuvanted vaccine developed by GlaxoSmithKline Biologicals. … [L46352] It was also later approved by Health Canada on August 4, 2023,[L47666] and the EMA in March 2025.[L52380]
Synonyms: RECOMBINANT RESPIRATORY SYNCYTIAL VIRUS PRE-FUSION F PROTEIN, RESPIRATORY SYNCYTIAL VIRUS PREFUSION F PROTEIN (RSVPREF3)Levomenthol
go.drugbank.com/drugs/DB00825ApprovedInvestigationalMenthol mediates anesthetic properties and anti-irritating properties locally, thus it is widely used to relieve minor throat irritations. … Menthol is a covalent organic compound made synthetically or obtained from peppermint or other mint oils.
Synonyms: (1R-(1-α,2-β,5-α))-5-methyl-2-(1-methylethyl)cyclohexanol, CYCLOHEXANOL, 5-METHYL-2-(1-METHYLETHYL)-, (1R-(1.ALPHA.,2.BETA.,5.ALPHA.))-Mixtures: CHAP ICE (R) MEDICATED, Ken- Ku Oil Cap Pancor MasHaloperidol
go.drugbank.com/drugs/DB00502ApprovedInvestigationalDopamine-antagonizing medications such as haloperidol are though to improve psychotic symptoms and states that are caused by an over-production of dopamine, such as schizophrenia, which is theorized to … the least amount of side effects within this class, but demonstrates a stronger disposition for causing extrapyramidal symptoms (EPS).
Synonyms: 1-(3-p-fluorobenzoylpropyl)-4-p-chlorophenyl-4-hydroxypiperidine, 4-[4-(4-chlorophenyl)-4-hydroxy-1-piperidyl]-1-(4-fluorophenyl)-butan-1-oneInternational brands: Einalon STopiramate
go.drugbank.com/drugs/DB00273ApprovedInvestigationalTopiramate is a anti-epileptic drug used to manage seizures and prevent migraines.[A175249] It was initially approved by the FDA in 1996. … [A175249] Interestingly, topiramate was discovered by chance when attempts were made to formulate a novel antidiabetic drug.[A188330]
Categories: P-glycoprotein substrates, Cytochrome P-450 CYP3A InducersSynonyms: 2,3:4,5-di-O-isopropylidene-β-D-fructopyranose sulfamate, 2,3:4,5-bis-O-(1-methylethylidene)-β-D-fructopyranose sulfamateIntron-associated endonuclease 1
go.drugbank.com/bio_entities/BE0002953TargetEnterobacteria phage T4This endonuclease is specific to the thymidylate synthase (td) gene splice junction and is involved in intron homing.
Synonyms: I-TevI