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Displaying results 971 - 980 of 10000 in total
  1. Drug

    Estradiol

    go.drugbank.com/drugs/DB00783
    ApprovedInvestigationalVet approved

    Estradiol is a naturally occurring hormone circulating endogenously in females. … It is commercially available in several hormone therapy products for managing conditions associated with reduced estrogen, such as vulvovaginal atrophy and hot flashes.

    Mixtures: KLIOGEST N, KLIOGEST NProducts: AKROFOLLINE 5 MG/ML IM AMPUL
  2. Drug

    TrenibotulinumtoxinE

    go.drugbank.com/drugs/DB19082
    Approved

    TrenibotulinumtoxinE is a botulinum neurotoxin serotype E, produced in *Clostridium botulinum*, used for the temporary improvement in the appearance of moderate to severe glabellar lines in adults. … [L64118] It is the first and only rapid-onset, short-duration botulinum neurotoxin serotype E approved in Europe.[L64118]

  3. Drug

    Glycine

    go.drugbank.com/drugs/DB00145
    ApprovedInvestigationalNutraceuticalVet approved

    It is found primarily in gelatin and silk fibroin and used therapeutically as a nutrient. It is also a fast inhibitory neurotransmitter.

    Mixtures: Aminosyn II in Dextrose, Aminosyn II in Dextrose
  4. Drug

    Cefixime

    go.drugbank.com/drugs/DB00671
    ApprovedInvestigational

    [A262995] Third-generation cephalosporins are often a first-line therapy against certain bacterial infections. … [A263031] Cefixime was first approved in the United States in 1986.[L49293]

    Products: CEFIXIMA INN-FARM
  5. Target

    Serine/threonine-protein kinase Nek9

    go.drugbank.com/bio_entities/BE0009500
    TargetHumans

    Pleiotropic regulator of mitotic progression, participating in the control of spindle dynamics and chromosome separation (PubMed:12101123, PubMed:12840024, PubMed:14660563, PubMed:19941817).

    Synonyms: Never in mitosis A-related kinase 9
  6. Drug

    Tolnaftate

    go.drugbank.com/drugs/DB00525
    ApprovedVet approved

    It is sold under several brand names, most notably Tinactin and Odor Eaters. … Tolnaftate is a synthetic over-the-counter anti-fungal agent. It may come as a cream, powder, spray, or liquid aerosol, and is used to treat jock itch, athlete's foot and ringworm.

    Synonyms: 2-Naphthyl N-methyl-N-(3-tolyl)thionocarbamate, N-methyl-N-(3-methylphenyl)-1-(naphthalen-2-yloxy)methanethioamideProducts: Opti-Nail 2-in-1, Ongo - Fin
  7. Drug

    Glofitamab

    go.drugbank.com/drugs/DB16371
    ApprovedInvestigational

    ) after two or more lines of systemic therapy. … , after two or more lines of systemic therapy under accelerated approval based on response rate and durability of response.

  8. Target

    Serine/threonine-protein kinase Nek2

    go.drugbank.com/bio_entities/BE0003796
    TargetHumans

    Protein kinase which is involved in the control of centrosome separation and bipolar spindle formation in mitotic cells and chromatin condensation in meiotic cells. … Involved in the regulation of centrosome disjunction (PubMed:26220856).

    Synonyms: Never in mitosis A-related kinase 2
  9. Target

    Splicing factor 1

    go.drugbank.com/bio_entities/BE0009118
    TargetHumans

    Necessary for the ATP-dependent first step of spliceosome assembly. Binds to the intron branch point sequence (BPS) 5'-UACUAAC-3' of the pre-mRNA. May act as transcription repressor

    Synonyms: Zinc finger gene in MEN1 locus
  10. Drug

    Triethylenetetramine

    go.drugbank.com/drugs/DB06824
    ApprovedInvestigational

    [A19333] Initially approved by the FDA in 1985 as a second-line treatment for Wilson's disease,[A19334] TETA is currently indicated to treat adults with stable Wilson’s disease who are de-coppered and … Triethylenetatramine (TETA), also known as trientine, is a potent and selective copper (II)-selective chelator. It is a structural analog of linear polyamine compounds, [spermidine] and [spermine].

    Categories: Compounds used in a research, industrial, or household setting