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Displaying results 971 - 980 of 10000 in total
  1. Target

    NKG2-A/NKG2-B type II integral membrane protein

    go.drugbank.com/bio_entities/BE0010560
    TargetHumans

    Dominantly counteracts T cell receptor signaling on a subset of memory/effector CD8-positive T cells as part of an antigen-driven response to avoid autoimmunity (PubMed:12387742). … In HLA-E-rich tumor microenvironment, acts as an immune inhibitory checkpoint and may contribute to progressive loss of effector functions of NK cells and tumor-specific T cells, a state known as cell

    Polypeptides: NKG2-A/NKG2-B type II integral membrane proteinSynonyms: NK cell receptor A, NKG2-A/B-activating NK receptor
  2. Drug

    Hyaluronidase

    go.drugbank.com/drugs/DB14740
    ApprovedInvestigational

    [A199026] Early research into hyaluronidase identified it as a "spreading factor" which allowed for increased permeability of the connective tissue. … Hyaluronidase is an enzyme used to improve the absorption and dispersion of parenterally administered fluids, drugs, and contrast agents.

    Products: POLVO LIOFILIZADO PARA RECONSTITUIR A SOLUCION PARA ADMINISTRACIÓN OFTALMICA, HYLASE® DESSAU 150 IU
  3. Drug

    Calcium

    go.drugbank.com/drugs/DB01373
    ApprovedInvestigationalNutraceutical

    The best-absorbed form of calcium from a pill is a calcium salt like carbonate or phosphate. Calcium gluconate and calcium lactate are absorbed well by pregnant women. … The skeleton acts as a major mineral storage site for the element and releases Ca2+ ions into the bloodstream under controlled conditions.

    Mixtures: Calcium A D, One A Day TabCategories: ascorbic acid (vit C) and calcium
  4. Drug

    Clostridium tetani toxoid antigen (formaldehyde inactivated)

    go.drugbank.com/drugs/DB10583
    ApprovedInvestigational

    Clostridium tetani toxoid antigen (formaldehyde inactivated) is a vaccine for intramuscular injection. … It is used for active immunization of children 7 years of age or older, and adults, for prevention of tetanus.

    Mixtures: 3 ANTIGEN, Neisvac-CProducts: TETAVAX single dose, suspension for injection in a prefilled syringe, T-VAC 0,5 ML IM ENJEKSIYON IÇIN SÜSPANSIYON IÇEREN AMPUL
  5. Drug

    Dupilumab

    go.drugbank.com/drugs/DB12159
    ApprovedInvestigational

    [L7186] Dupilumab is commonly marketed as Dupixent, which is available as a formulation for subcutaneous injection. It was first approved by the FDA in 2017. … Dupilumab is a fully human monoclonal antibody of the immunoglobulin G4 subclass that binds to the interleukin-4 (IL-4) receptor, inhibiting the receptor signaling pathways.

    Categories: Interleukin-4 Receptor alpha Antagonist, Interleukin 4 Receptor alpha AntagonistsProducts: DUPIXENT SOLUTION FOR INJECTION IN A PRE-FILLED SYRINGE 300 mg/2ml, DUPIXENT SOLUTION FOR INJECTION IN A PRE-FILLED SYRINGE 200 mg/1.14ml
  6. Indication

    Mucopolysaccharidosis Type IVA

    go.drugbank.com/conditions/DBCOND0060256
    Drugs: Elosulfase alfa
    Synonyms: MPS IV-A-Mucopolysaccharidosis IV-A, Morquio A Disease
  7. Drug

    Sus scrofa skin

    go.drugbank.com/drugs/DB10606
    Approved

    Sus scrofa skin or pelt is used in allergenic testing.

    Products: PiGe ll Real Skin Eye, PiGe ll Real Skin Neck Pack
  8. Drug

    Ammonium lactate

    go.drugbank.com/drugs/DB06768
    Approved

    Ammonium lactate is the ammonium salt of lactic acid.

    Mixtures: Ultravate X, Ultravate XProducts: Lac-Hydrin, Lac Hydrin Cream
  9. Drug

    Dimethicone

    go.drugbank.com/drugs/DB11074
    ApprovedInvestigational

    Dimethicone is a silicone oil that is also known as polydimethylsiloxane (PDMS). It has viscoelastic properties. … A study found that that the 100 % dimethicone product is a safe and highly effective head lice treatment for children and may serve as less toxic and less resistance-prone alternative to pesticide-containing

    Mixtures: A AND A Diaper Rash cream, A and DCategories: Compounds used in a research, industrial, or household setting
  10. Drug

    Insulin detemir

    go.drugbank.com/drugs/DB01307
    ApprovedInvestigational

    , which is a life-threatening medical emergency. … Insulin detemir is a long-acting form of insulin used for the treatment of hyperglycemia caused by Type 1 and Type 2 Diabetes.

    Categories: Cytochrome P-450 CYP1A2 Inducers, Cytochrome P-450 Enzyme InducersProducts: Levemir FlexPen 100U/ML Solution for injection in a prefilled pen, Levemir® FlexPen® 100 U/ml Solution for Injection in Pre-filled Pen