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Displaying results 9881 - 9890 of 10000 in total
  1. Drug

    COVID-19 convalescent plasma

    go.drugbank.com/drugs/DB15692
    Investigational

    COVID-19 patients is safe. … [L14333] This investigational COVID-19 treatment is currently available through three main pathways: use in registered clinical trials, use through the expanded access COVID-19 protocol (21 CFR 312.305

  2. Drug

    RGX-111

    go.drugbank.com/drugs/DB17632
    Investigational

    Developed by REGENXBIO Inc., it was investigated for the treatment of mucopolysaccharidosis Type I (MPS I).[L46666] … RGX-111 is an adeno-associated virus vector AAV9 designed to deliver the α-L-iduronidase (IDUA) gene.

    Synonyms: Adeno-associated virus vector serotype 9 expressing human a-L-iduronidase
  3. Drug

    Fenobam

    go.drugbank.com/drugs/DB12931
    Investigational

    Fenobam is under investigation in clinical trial NCT00637221 (Open Label Study Investigating Safety and Efficacy of Fenobam anhydrous 50 mg - 150 mg on Prepulse Inhibition Tests and Continuous Performance

  4. Drug

    BBIBP-CorV

    go.drugbank.com/drugs/DB15807
    Investigational

    As of August 2020, this vaccine is being tested for prophylaxis against COVID-19 in human clinical trials. … Investigation shows this vaccine induces neutralizing antibodies in several mammalian species while also showing protective efficacy with SARS-CoV-2 challenge in rhesus macaques[A219763].

  5. Drug

    Horse chestnut

    go.drugbank.com/drugs/DB13195
    Investigational

    Its therapeutic potential in the treatment of chronic venous insufficiency is being studied. … Horse chestnut is a flowering plant commonly referred to as *Aesculus hippocastanum*.

  6. Drug

    INO-4800

    go.drugbank.com/drugs/DB15693
    Investigational

    INO-4800 is a DNA vaccine containing the full sequence for the SARS-CoV-2 Spike (S) protein in development for immunization against COVID-19. … [A214475, A214478] Follow up studies in both BALB/c mice and Hartley guinea pigs demonstrated the ability of INO-4800 to induce both humoral and T cell-mediated immunity against SARS-CoV-2, including in

  7. Drug

    AEM-28

    go.drugbank.com/drugs/DB17642
    Investigational

    AEM-28 is a 28 amino acid mimetic of apolipoprotein E being investigated for lipid disorders, such as homozygous familial hypercholesterolemia. It possesses anti-inflammatory properties.[A258764]

  8. Drug

    NOP-1A

    go.drugbank.com/drugs/DB15208
    Investigational

    NOP-1A is under investigation in clinical trial NCT01198197 (PET Brain and Whole Body Distribution Studies for Nociceptin/Orphanin FQ Peptide (NOP) Receptor Using [11C]NOP-1A).

  9. Drug

    Sofituzumab vedotin

    go.drugbank.com/drugs/DB15349
    Investigational

    Sofituzumab vedotin is under investigation in clinical trial NCT01335958 (Safety and Pharmacokinetics of DMUC5754A Administered Intravenously to Patients With Platinum-Resistant Ovarian Cancer or Unresectable

  10. Drug

    Timbetasin

    go.drugbank.com/drugs/DB19119
    Investigational

    Timbetasin is under investigation in clinical trial NCT05555589 (Assessment of the Safety and Efficacy of 0.1% RGN-259 Ophthalmic Solution for the Treatment of NK: SEER-2).

    Synonyms: Ac-ser-asp-lys-pro-asp-met-ala-glu-ile-glu-lys-phe-asp-lys-ser-lys-leu-lys-lys-thr-glu-thr-gln-glu-lys-asn-pro-leu-pro-ser-lys-glu-thr-ile-glu-gln-glu-lys-gln-ala-gly-glu-ser, N-ACETYL-L-SERYL-L-ASPARTYL-L-LYSYL-L-PROLYL-L-ASPARTYL-L-METHIONYL-L-ALANYL-L-GLUTAMYL-L-ISOLEUCYL-L-GLUTAMYL-L-LYSYL-L-PHENYLALANYL-L-ASPARTYL-L-LYSYL-L-SERYL-L-LYSYL-L-LEUCYL-L-LYSYL-L-LYSYL-L-THEONYL-L-GLUTAMYL-L-THEONYL-L-GLUTAMINYL-L-GLUTAMYL-L-LYS