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Displaying results 1 - 10 of 172 in total
  1. Target

    Sucrose porin

    go.drugbank.com/bio_entities/BE0002835
    TargetSalmonella typhimurium

    Porin for sucrose uptake.

    Polypeptides: Sucrose porinSynonyms: Sucrose porin precursor
  2. Target

    Protein disulfide-isomerase

    go.drugbank.com/bio_entities/BE0009177
    TargetPlasmodium falciparum (isolate 3D7)

    Polypeptides: Protein disulfide-isomeraseFunction: protein disulfide isomerase activity
  3. Target

    Protein disulfide-isomerase

    go.drugbank.com/bio_entities/BE0002467
    TargetHumans

    This multifunctional protein catalyzes the formation, breakage and rearrangement of disulfide bonds. … Receptor for LGALS9; the interaction retains P4HB at the cell surface of Th2 T helper cells, increasing disulfide reductase activity at the plasma membrane, altering the plasma membrane redox state and

    Polypeptides: Protein disulfide-isomerase
  4. Target

    Dual adapter for phosphotyrosine and 3-phosphotyrosine and 3-phosphoinositide

    go.drugbank.com/bio_entities/BE0001300
    TargetHumans

    May act as a B-cell-associated adapter that regulates B-cell antigen receptor (BCR)-signaling downstream of PI3K

    Polypeptides: Dual adapter for phosphotyrosine and 3-phosphotyrosine and 3-phosphoinositide
  5. Target

    Protein disulfide-isomerase A3

    go.drugbank.com/bio_entities/BE0008980
    TargetHumans

    Protein disulfide isomerase that catalyzes the formation, isomerization, and reduction or oxidation of disulfide bonds in client proteins and functions as a protein folding chaperone (PubMed:11825568, … Core component of the major histocompatibility complex class I (MHC I) peptide loading complex where it functions as an essential folding chaperone for TAPBP.

    Polypeptides: Protein disulfide-isomerase A3Synonyms: Disulfide isomerase ER-60
  6. Target

    Sodium- and chloride-dependent neutral and basic amino acid transporter B(0+)

    go.drugbank.com/bio_entities/BE0000423
    TargetTransporterHumans

    Transports non-alpha-amino acids such as beta-alanine with low affinity, and has a higher affinity for dipolar and cationic amino acids such as leucine and lysine (PubMed:18599538). … Can also transport carnitine, butirylcarnitine and propionylcarnitine coupled to the transmembrane gradients of Na(+) and Cl(-) (PubMed:17855766)

    Polypeptides: Sodium- and chloride-dependent neutral and basic amino acid transporter B(0+)
  7. Target

    B- and T-lymphocyte attenuator

    go.drugbank.com/bio_entities/BE0010629
    TargetHumans

    Inhibitory receptor on lymphocytes that negatively regulates antigen receptor signaling via PTPN6/SHP-1 and PTPN11/SHP-2 (PubMed:12796776, PubMed:14652006, PubMed:15568026, PubMed:18193050). … In cis interactions, appears to play an immune regulatory role inhibiting in trans interactions in naive T cells to maintain a resting state.

    Polypeptides: B- and T-lymphocyte attenuatorSynonyms: B- and T-lymphocyte-associated protein
  8. Target

    Disulfide bond formation protein B

    go.drugbank.com/bio_entities/BE0004378
    TargetEscherichia coli (strain K12)

    MgrB acts between DsbA/DsbB and PhoP/PhoQ in this pathway. … Required for disulfide bond formation in some periplasmic proteins such as PhoA or OmpA. Acts by oxidizing the DsbA protein.

    Polypeptides: Disulfide bond formation protein BSynonyms: Disulfide oxidoreductase
  9. Target

    Splicing factor, proline- and glutamine-rich

    go.drugbank.com/bio_entities/BE0008965
    TargetHumans

    The SFPQ-NONO-NR5A1 complex binds to the CYP17 promoter and regulates basal and cAMP-dependent transcriptional activity. … DNA- and RNA binding protein, involved in several nuclear processes.

    Polypeptides: Splicing factor, proline- and glutamine-rich
  10. Target

    Cocaine- and amphetamine-regulated transcript protein

    go.drugbank.com/bio_entities/BE0000867
    TargetHumans

    Satiety factor closely associated with the actions of leptin and neuropeptide Y; this anorectic peptide inhibits both normal and starvation-induced feeding and completely blocks the feeding response induced … It promotes neuronal development and survival in vitro

    Polypeptides: Cocaine- and amphetamine-regulated transcript protein