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Lidocaine (Local Anaesthetic) Action Pathway
smpdb.ca/view/SMP0000398Drug actionOnce inside the cytoplasm, it is protonated and this protonated form enters and blocks the pore of the voltage-gated sodium channel from the cytoplasmic side.
Lidocaine (Antiarrhythmic) Action Pathway
smpdb.ca/view/SMP0000328Drug actionThe extra sodium and calcium ions that entered the cell during the action potential are extruded via sodium-potassium ATPases and NCX and intra- and extracellular ion concentrations are restored. … Membrane ion pumps, such as the sodium-potassium ATPase and sodium-calcium exchanger (NCX), maintain low intracellular sodium (5 mM) and calcium (100 nM) concentrations and high intracellular potassium
Lidocaine (Local Anaesthetic) Metabolism Pathway
smpdb.ca/view/SMP0000620Drug metabolismOnce inside the cytoplasm, it is protonated and this protonated form enters and blocks the pore of the voltage-gated sodium channel from the cytoplasmic side.
Lidocaine NMDA Anesthetic Action Pathway
smpdb.ca/view/SMP0126262Drug actionEver since its discovery and availability for sale and use in the late 1940s, lidocaine has become an exceptionally commonly used medication. … Lidocaine is a local anesthetic used in a wide variety of superficial and invasive procedures.
Lidocaine Sodium Channel Cardiac Muscle Relaxation Action Pathway
smpdb.ca/view/SMP0126504Drug action, conduction rate, and force of contraction. … Ever since its discovery and availability for sale and use in the late 1940s, lidocaine has become an exceptionally commonly used medication.