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Displaying results 1 - 10 of 2757 in total
  1. Target

    Protein kinase C

    go.drugbank.com/bio_entities/BE0004895
    TargetEnzymeHumans

    synthesis, protein-DNA ratio and cell surface area. … Calcium-independent, phospholipid- and diacylglycerol (DAG)-dependent serine/threonine-protein kinase that plays contrasting roles in cell death and cell survival by functioning as a pro-apoptotic protein

    Polypeptides: Protein kinase C alpha type, Protein kinase C beta typeSynonyms: Atypical protein kinase C-lambda/iota, Tyrosine-protein kinase PRKCD
  2. Target

    Surfactant protein C

    go.drugbank.com/bio_entities/BE0012617
    TargetHumans

    Pulmonary surfactant associated proteins promote alveolar stability by lowering the surface tension at the air-liquid interface in the peripheral air spaces

    Polypeptides: Surfactant protein CSynonyms: Pulmonary surfactant-associated protein C, SP-C
  3. Target

    Protein c-Fos

    go.drugbank.com/bio_entities/BE0001126
    TargetHumans

    Nuclear phosphoprotein which forms a tight but non-covalently linked complex with the JUN/AP-1 transcription factor. In the heterodimer, FOS and JUN/AP-1 basic regions each seems to interact with symmetrical DNA half sites. On TGF-beta a...

    Polypeptides: Protein c-FosSynonyms: G0/G1 switch regulatory protein 7, Proto-oncogene c-Fos
  4. Target

    Endothelial protein C receptor

    go.drugbank.com/bio_entities/BE0001161
    TargetHumans

    Binds activated protein C. Enhances protein C activation by the thrombin-thrombomodulin complex; plays a role in the protein C pathway controlling blood coagulation

    Polypeptides: Endothelial protein C receptorSynonyms: Activated protein C receptor, Endothelial cell protein C receptor
  5. Target

    Mannose-binding protein C

    go.drugbank.com/bio_entities/BE0004482
    TargetHumans

    Calcium-dependent lectin, which acts as a pattern recognition receptor that initiates the lectin pathway of the complement system, a cascade of proteins that leads to phagocytosis and breakdown of pathogens

    Polypeptides: Mannose-binding protein CSynonyms: Mannan-binding protein, MBP-C
  6. Target

    Osmotically inducible protein C

    go.drugbank.com/bio_entities/BE0002704
    TargetThermus thermophilus

    Polypeptides: Osmotically inducible protein C
  7. Target

    C protein alpha-antigen

    go.drugbank.com/bio_entities/BE0003314
    TargetStreptococcus agalactiae serotype Ia (strain ATCC 27591 / A909 / CDC SS700)

    May play a role in both virulence and immunity.

    Polypeptides: C protein alpha-antigenSynonyms: C protein alpha-antigen precursor
  8. Target

    Protein C-ets-1

    go.drugbank.com/bio_entities/BE0012759
    TargetHumans

    Transcription factor (PubMed:10698492, PubMed:11909962). Directly controls the expression of cytokine and chemokine genes in a wide variety of different cellular contexts (PubMed:20378371). May control the differentiation, survival and p...

    Polypeptides: Protein C-ets-1
  9. Target

    Aurora kinase C

    go.drugbank.com/bio_entities/BE0004601
    TargetHumans

    Phosphorylates TACC1, another protein involved in cell division, at 'Ser-228' … Serine/threonine-protein kinase component of the chromosomal passenger complex (CPC), a complex that acts as a key regulator of mitosis.

    Polypeptides: Aurora kinase CSynonyms: Serine/threonine-protein kinase aurora-C, Aurora/IPL1/Eg2 protein 2
  10. Target

    Protein kinase C epsilon type

    go.drugbank.com/bio_entities/BE0003431
    TargetHumans

    Phosphorylates and activates LRRK1, which phosphorylates RAB proteins involved in intracellular trafficking (PubMed:36040231). … Involved in the control of the directional transport of ITGB1 in mesenchymal cells by phosphorylating vimentin (VIM), an intermediate filament (IF) protein.

    Polypeptides: Protein kinase C epsilon typeFunction: 14-3-3 protein binding