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  1. Pathway

    Quinapril Action Pathway

    smpdb.ca/view/SMP0000153
    Drug action

    Quinapril is a prodrug which, following oral administration, undergoes biotransformation in vivo into its active form quinaprilat via cleavage of its ester group by the liver. … Quinapril (trade name: Accupril) belongs to the class of drugs known as angiotensin-converting enzyme (ACE) inhibitors and is used primarily to lower high blood pressure (hypertension).

    Drugs: Quinapril · Potassium cation · Zinc
  2. Pathway

    Quinapril Metabolism Pathway

    smpdb.ca/view/SMP0000596
    Drug metabolism

    Quinapril is a prodrug which, following oral administration, undergoes biotransformation in vivo into its active form quinaprilat via cleavage of its ester group by the liver. … Quinapril (trade name: Accupril) belongs to the class of drugs known as angiotensin-converting enzyme (ACE) inhibitors and is used primarily to lower high blood pressure (hypertension).

    Drugs: Quinapril · Zinc
  3. Pathway

    Quinapril ACE Inhibitor Action Pathway

    smpdb.ca/view/SMP0123094
    Drug action

    Quinapril is converted into Quinaprilat through the liver after being ingested which travels in the blood to inhibit ACE which is from the lungs. … Quinapril is angiotensin-converting enzyme (ACE) inhibitor for the conversion of angiotensin I into angiotensin II.

    Drugs: Glutamic acid · Quinapril · Zinc
  4. Pathway

    Hydrochlorothiazide Drug Metabolism

    smpdb.ca/view/SMP0130739
    Metabolic

    Hydrochlorothiazide is a drug that is not metabolized by the human body as determined by current research and biotransformer analysis. Hydrochlorothiazide passes through the liver and is then excreted from the body mainly through the kid...

    Drugs: Hydrochlorothiazide
  5. Pathway

    Hydrochlorothiazide Action Pathway

    smpdb.ca/view/SMP0000100
    Drug action

    Hydroflumethiazide (also known as Esidrix or Oretic) is an organic compound that used for diuretic. It can inhibit the solute carrier family 12 member 3 (also known as sodium-chloride symporter) in the nephron to prevent water reabsorpti...

    Drugs: Cysteine · Hydrochlorothiazide · Potassium cation · Urea
  6. Pathway

    Hydrochlorothiazide Diuretic Action Pathway

    smpdb.ca/view/SMP0122688
    Drug action

    Hydrochlorothiazide is an oral diuretic drug that acts in the kidney, specifically in the distal convoluted tubule of the nephron. It is used to treat conditions such as hypertension, heart failure, severe resistant edema, nephrogenic di...

    Drugs: Hydrochlorothiazide · Potassium cation · Calcium