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Displaying results 1 - 10 of 24 in total
  1. Drug

    Quinapril

    go.drugbank.com/drugs/DB00881
    ApprovedInvestigational

    Quinapril is the ethyl ester prodrug of the non-sulfhydryl angiotensin converting enzyme inhibitor quinaprilat.[L8420,L8423] It is used to treat hypertension and heart failure. … [A184844] Quinapril was granted FDA approval on 19 November 1991.[L8420] A combination tablet with [hydrochlorothiazide] was also approved on 28 December 1999.[L8423]

    Synonyms: Quinapril, QuinaprilumInternational brands: Quinazil
  2. Pathway

    Quinapril Action Pathway

    smpdb.ca/view/SMP0000153
    Drug action

    Quinapril is a prodrug which, following oral administration, undergoes biotransformation in vivo into its active form quinaprilat via cleavage of its ester group by the liver. … Quinapril (trade name: Accupril) belongs to the class of drugs known as angiotensin-converting enzyme (ACE) inhibitors and is used primarily to lower high blood pressure (hypertension).

    Drugs: Quinapril · Potassium cation · Zinc
  3. Pathway

    Quinapril Metabolism Pathway

    smpdb.ca/view/SMP0000596
    Drug metabolism

    Quinapril is a prodrug which, following oral administration, undergoes biotransformation in vivo into its active form quinaprilat via cleavage of its ester group by the liver. … Quinapril (trade name: Accupril) belongs to the class of drugs known as angiotensin-converting enzyme (ACE) inhibitors and is used primarily to lower high blood pressure (hypertension).

    Drugs: Quinapril · Zinc
  4. Pathway

    Quinapril ACE Inhibitor Action Pathway

    smpdb.ca/view/SMP0123094
    Drug action

    Quinapril is converted into Quinaprilat through the liver after being ingested which travels in the blood to inhibit ACE which is from the lungs. … Quinapril is angiotensin-converting enzyme (ACE) inhibitor for the conversion of angiotensin I into angiotensin II.

    Drugs: Glutamic acid · Quinapril · Zinc
  5. Drug

    Hydrochlorothiazide

    go.drugbank.com/drugs/DB00999
    ApprovedInvestigationalVet approved

    Hydrochlorothiazide is the most commonly prescribed thiazide diuretic. It is indicated to treat edema and hypertension. Hydrochlorothiazide use is common but declining in favour of angiotensin converting enzyme inhibitors. Many combinati...

    Mixtures: Quinapril Hydrochloride and Hydrochlorothiazide, Quinapril Hydrochloride and HydrochlorothiazideProducts: HYDROCHLORZIDE-50 TABLET, HYDROCHLORZIDE-25 TABLET
  6. Indication

    Left Ventricular Dysfunction

    go.drugbank.com/conditions/DBCOND0031407
    Drugs: Enalaprilat · Ivabradine · Quinapril · Trandolapril
  7. Indication

    Congestive Heart Failure (CHF)

    go.drugbank.com/conditions/DBCOND0033011
    Drugs: Amiloride · Captopril · Cilazapril · Delapril · Enoximone · Eprosartan +7 more
  8. Indication

    Diabetic Nephropathy

    go.drugbank.com/conditions/DBCOND0028920
    Drugs: Benazepril · Candesartan cilexetil · Captopril · Enalapril · Enalaprilat · Eprosartan +9 more
  9. Indication

    Hypertension

    go.drugbank.com/conditions/DBCOND0020037
    Drugs: Acebutolol · Aliskiren · Amiloride · Amlodipine · Ammonium chloride · Aprocitentan +78 more
  10. Indication

    Calcium Nephrolithiasis

    go.drugbank.com/conditions/DBCOND0036164
    Drugs: Amiloride · Chlorthalidone · Hydrochlorothiazide · beta-Pinene