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Benzocaine Action Pathway
smpdb.ca/view/SMP0000392Drug actionBenzocaine exerts its local anaesthetic effect by blocking voltage-gated sodium channels in peripheral neurons. Benzocaine diffuses across the neuronal plasma membrane in its uncharged base form. Once inside the cytoplasm, it is protonat...
Metabolism and Physiological Effects of Hippuric Acid
smpdb.ca/view/SMP0123209MetabolicHippuric acid is an acyl glycine present in normal urine. This uremic toxin’s presence increases with consumption of phenol-rich foods (e.g. tea, wine, fruit juice, etc.). Polyphenols are converted into benzoic acid, which then follows t...
Salicylate-Sodium NSAID Action Pathway
smpdb.ca/view/SMP0124630Drug actionSalicylate-sodium is an NSAID which possesses anti-inflammatory, analgesic and antipyretic activity. It targets the prostaglandin G/H synthase-1 (COX-1) and prostaglandin G/H synthase-2 (COX-2) in the cyclooxygenase pathway. The cyclooxy...
Salicylate-Sodium Action Pathway
smpdb.ca/view/SMP0000708Drug actionSalicylate-sodium (also named salsonin or clin) is a nonsteroidal anti-inflammatory drug (NSAID). It can be used for relieving pain and reducing fever. Salicylate-sodium can block prostaglandin synthesis by the action of inhibition of pr...
Drugs: Glutamic acid · Glutathione · Dinoprostone · Calcium · Magnesium cation · Salicylic acid +5 moreSalicylic Acid COX Action Pathway
smpdb.ca/view/SMP0124590Drug actionSalicylic acid is an acid used to treat acne, psoriasis, calluses, corns, keratosis pilaris, and warts. Salicylate's use in rheumatic diseases is due to it's analgesic and anti-inflammatory activity. It targets the prostaglandin G/H synt...
Salicylic Acid Action Pathway
smpdb.ca/view/SMP0000709Drug actionSalicylic acid (also named rutranex or salonil) is a nonsteroidal anti-inflammatory drug. Salicylic acid is also an important active metabolite of aspirin (acetylsalicylic acid). It can be used to reduce pain and fever. Salicylic acid ca...
Drugs: Glutamic acid · Glutathione · Dinoprostone · Salicylic acid · Calcium · Magnesium cation +5 moreMetabolism and Physiological Effects of 4-Hydroxyhippuric Acid
smpdb.ca/view/SMP0125537Metabolic4-Hydroxyhippuric, also known as 4-hydroxybenzoylglycine or 4-hydroxyhippate acid, is a metabolite of hippuric acid, and a uremic toxin. Benzoic acid is present in many fruits, such as apricots, prunes, and berries; many vegetables such ...