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Displaying results 1 - 10 of 195 in total
  1. Target

    Homeobox protein engrailed-2

    go.drugbank.com/bio_entities/BE0004484
    TargetHumans

    Synonyms: Hu-En-2, Homeobox protein en-2
  2. Target

    Nuclear cap-binding protein subunit 1

    go.drugbank.com/bio_entities/BE0014101
    TargetHumans

    The CBC complex is also involved in 'failsafe' NMD, which is independent of the EJC complex, while it does not participate in Staufen-mediated mRNA decay (SMD). … The CBC complex enhances NMD in mRNAs containing at least one exon-junction complex (EJC) via its interaction with UPF1, promoting the interaction between UPF1 and UPF2.

    Synonyms: NCBP 80 kDa subunit, 80 kDa nuclear cap-binding protein
  3. Target

    Transitional endoplasmic reticulum ATPase

    go.drugbank.com/bio_entities/BE0004572
    TargetHumans

    The NPLOC4-UFD1-VCP complex regulates spindle disassembly at the end of mitosis and is necessary for the formation of a closed nuclear envelope. … Mediates the endoplasmic reticulum-associated degradation of CHRNA3 in cortical neurons as part of the STUB1-VCP-UBXN2A complex (PubMed:26265139).

    Synonyms: 15S Mg(2+)-ATPase p97 subunit
  4. Target

    Diacylglycerol kinase alpha

    go.drugbank.com/bio_entities/BE0002324
    TargetHumans

    Also plays an important role in the biosynthesis of complex lipids (Probable).

    Synonyms: 80 kDa diacylglycerol kinase
  5. Target

    Myristoylated alanine-rich C-kinase substrate

    go.drugbank.com/bio_entities/BE0012891
    TargetHumans

    Membrane-associated protein that plays a role in the structural modulation of the actin cytoskeleton, chemotaxis, motility, cell adhesion, phagocytosis, and exocytosis through lipid sequestering and/or protein docking to membranes (PubMe...

    Synonyms: Protein kinase C substrate, 80 kDa protein, light chain
  6. Target

    Interleukin-6 receptor subunit alpha

    go.drugbank.com/bio_entities/BE0002859
    TargetHumans

    Part of the receptor for interleukin 6. Binds to IL6 with low affinity, but does not transduce a signal (PubMed:28265003). Signal activation necessitate an association with IL6ST. Activation leads to the regulation of the immune response...

    Synonyms: Membrane glycoprotein 80
  7. Target

    Protein S100-A12

    go.drugbank.com/bio_entities/BE0001206
    TargetHumans

    S100A12 is a calcium-, zinc- and copper-binding protein which plays a prominent role in the regulation of inflammatory processes and immune response.

    Synonyms: EN-RAGE
  8. Target

    Interleukin enhancer-binding factor 3

    go.drugbank.com/bio_entities/BE0014107
    TargetHumans

    RNA-binding protein that plays an essential role in the biogenesis of circular RNAs (circRNAs) which are produced by back-splicing circularization of pre-mRNAs. Within the nucleus, promotes circRNAs processing by stabilizing the regulato...

    Synonyms: Translational control protein 80
  9. Target

    Copper

    go.drugbank.com/bio_entities/BE0004825
    TargetHumans

  10. Target

    Copper-containing nitrite reductase

    go.drugbank.com/bio_entities/BE0001495
    TargetAchromobacter cycloclastes

    Polypeptides: Copper-containing nitrite reductaseFunction: copper ion binding