Search

Displaying all 9 results
  1. Target

    Homeobox protein engrailed-2

    go.drugbank.com/bio_entities/BE0004484
    TargetHumans

    Synonyms: Hu-En-2, Homeobox protein en-2
  2. Target

    Nuclear cap-binding protein subunit 1

    go.drugbank.com/bio_entities/BE0014101
    TargetHumans

    Component of the cap-binding complex (CBC), which binds cotranscriptionally to the 5'-cap of pre-mRNAs and is involved in various processes such as pre-mRNA splicing, translation regulation, nonsense-mediated mRNA decay, RNA-mediated gen...

    Synonyms: NCBP 80 kDa subunit, 80 kDa nuclear cap-binding protein
  3. Target

    Transitional endoplasmic reticulum ATPase

    go.drugbank.com/bio_entities/BE0004572
    TargetHumans

    Necessary for the fragmentation of Golgi stacks during mitosis and for their reassembly after mitosis. Involved in the formation of the transitional endoplasmic reticulum (tER). The transfer of membranes from the endoplasmic reticulum to...

    Synonyms: 15S Mg(2+)-ATPase p97 subunit
  4. Target

    Diacylglycerol kinase alpha

    go.drugbank.com/bio_entities/BE0002324
    TargetHumans

    Diacylglycerol kinase that converts diacylglycerol/DAG into phosphatidic acid/phosphatidate/PA and regulates the respective levels of these two bioactive lipids (PubMed:15544348, PubMed:2175712). Thereby, acts as a central switch between...

    Synonyms: 80 kDa diacylglycerol kinase
  5. Target

    Myristoylated alanine-rich C-kinase substrate

    go.drugbank.com/bio_entities/BE0012891
    TargetHumans

    Membrane-associated protein that plays a role in the structural modulation of the actin cytoskeleton, chemotaxis, motility, cell adhesion, phagocytosis, and exocytosis through lipid sequestering and/or protein docking to membranes (PubMe...

    Synonyms: Protein kinase C substrate, 80 kDa protein, light chain
  6. Target

    Interleukin-6 receptor subunit alpha

    go.drugbank.com/bio_entities/BE0002859
    TargetHumans

    Part of the receptor for interleukin 6. Binds to IL6 with low affinity, but does not transduce a signal (PubMed:28265003). Signal activation necessitate an association with IL6ST. Activation leads to the regulation of the immune response...

    Synonyms: Membrane glycoprotein 80
  7. Target

    Protein S100-A12

    go.drugbank.com/bio_entities/BE0001206
    TargetHumans

    S100A12 is a calcium-, zinc- and copper-binding protein which plays a prominent role in the regulation of inflammatory processes and immune response. Its pro-inflammatory activity involves recruitment of leukocytes, promotion of cytokine...

    Synonyms: EN-RAGE
  8. Target

    Interleukin enhancer-binding factor 3

    go.drugbank.com/bio_entities/BE0014107
    TargetHumans

    RNA-binding protein that plays an essential role in the biogenesis of circular RNAs (circRNAs) which are produced by back-splicing circularization of pre-mRNAs. Within the nucleus, promotes circRNAs processing by stabilizing the regulato...

    Synonyms: Translational control protein 80
  9. Target

    Diacylglycerol kinase

    go.drugbank.com/bio_entities/BE0009935
    TargetHumans

    Diacylglycerol kinase that converts diacylglycerol/DAG into phosphatidic acid/phosphatidate/PA and regulates the respective levels of these two bioactive lipids (PubMed:15544348, PubMed:2175712). Thereby, acts as a central switch between...

    Synonyms: 80 kDa diacylglycerol kinase