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Displaying results 1 - 10 of 104 in total
  1. Target

    Calcitonin gene-related peptides

    go.drugbank.com/bio_entities/BE0010233
    TargetHumans

    CGRP1/CALCA is a peptide hormone that induces vasodilation mediated by the CALCRL-RAMP1 receptor complex (PubMed:1318039, PubMed:33602864, PubMed:9620797). Dilates a variety of vessels including the coronary, cerebral and systemic vascul...

    Polypeptides: Calcitonin gene-related peptide 1, Calcitonin gene-related peptide 2Synonyms: Calcitonin gene-related peptide I, Calcitonin gene-related peptide II
  2. Target

    Lymphocyte activation gene 3 protein

    go.drugbank.com/bio_entities/BE0010189
    TargetHumans

    Inhibitory receptor on antigen activated T-cells (PubMed:20421648, PubMed:35761082, PubMed:7805750, PubMed:8647185). Delivers inhibitory signals upon binding to ligands, such as MHC class II, its main ligand present at the surface of ant...

    Polypeptides: Lymphocyte activation gene 3 protein
  3. Target

    Tumor susceptibility gene 101 protein

    go.drugbank.com/bio_entities/BE0019070
    TargetHumans

    Component of the ESCRT-I complex, a regulator of vesicular trafficking process. Binds to ubiquitinated cargo proteins and is required for the sorting of endocytic ubiquitinated cargos into multivesicular bodies (MVBs). Mediates the assoc...

    Polypeptides: Tumor susceptibility gene 101 protein
  4. Target

    Insulin-induced gene 2 protein

    go.drugbank.com/bio_entities/BE0021304
    TargetHumans

    Oxysterol-binding protein that mediates feedback control of cholesterol synthesis by controlling both endoplasmic reticulum to Golgi transport of SCAP and degradation of HMGCR (PubMed:12242332, PubMed:16606821, PubMed:32322062). Acts as ...

    Polypeptides: Insulin-induced gene 2 protein
  5. Target

    Insulin-induced gene 1 protein

    go.drugbank.com/bio_entities/BE0011639
    TargetHumans

    Oxysterol-binding protein that mediates feedback control of cholesterol synthesis by controlling both endoplasmic reticulum to Golgi transport of SCAP and degradation of HMGCR (PubMed:12202038, PubMed:12535518, PubMed:16168377, PubMed:16...

    Polypeptides: Insulin-induced gene 1 protein
  6. Target

    Calcitonin gene-related peptide 1

    go.drugbank.com/bio_entities/BE0001103
    TargetHumans

    CGRP1/CALCA is a peptide hormone that induces vasodilation mediated by the CALCRL-RAMP1 receptor complex (PubMed:1318039, PubMed:33602864, PubMed:9620797). Dilates a variety of vessels including the coronary, cerebral and systemic vascul...

    Polypeptides: Calcitonin gene-related peptide 1Synonyms: Calcitonin gene-related peptide I
  7. Target

    Calcitonin gene-related peptide 2

    go.drugbank.com/bio_entities/BE0002370
    TargetHumans

    CALCB/CGRP2 is a peptide hormone that induces vasodilation mediated by the CALCRL-RAMP1 receptor complex (PubMed:1318039, PubMed:9620797). Dilates a variety of vessels including the coronary, cerebral and systemic vasculature. Its abunda...

    Polypeptides: Calcitonin gene-related peptide 2Synonyms: Calcitonin gene-related peptide II
  8. Target

    Interferon-stimulated gene 20 kDa protein

    go.drugbank.com/bio_entities/BE0001938
    TargetHumans

    Interferon-induced antiviral exoribonuclease that acts mainly on single-stranded RNA (PubMed:11401564, PubMed:12594219, PubMed:16033969). Exhibits antiviral activity against RNA viruses including hepatitis C virus (HCV), hepatitis A viru...

    Polypeptides: Interferon-stimulated gene 20 kDa protein
  9. Target

    DMD-001 gene (exon 51 target site)

    go.drugbank.com/bio_entities/BE0008666
    TargetHumans

  10. Target

    Calcitonin gene-related peptide type 1 receptor

    go.drugbank.com/bio_entities/BE0009009
    TargetHumans

    Together with RAMP1, form the receptor complex for calcitonin-gene-related peptides CALCA/CGRP1 and CALCB/CGRP2 (PubMed:33602864).

    Polypeptides: Calcitonin gene-related peptide type 1 receptor