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Bifunctional PGK/TIM
go.drugbank.com/bio_entities/BE0001611TargetThermotoga maritima (strain ATCC 43589 / MSB8 / DSM 3109 / JCM 10099)Polypeptides: Bifunctional PGK/TIMSynonyms: TIMImmunoglobulin heavy constant gamma 2
go.drugbank.com/bio_entities/BE0003805TargetHumansConstant region of immunoglobulin (Ig) heavy chains. Igs are membrane-bound or secreted glycoproteins produced by B lymphocytes. In the recognition phase of humoral immunity, the membrane-bound Igs serve as receptors, which upon binding ...
Synonyms: Ig gamma-2 chain C region TILTyrosine-protein kinase receptor Tie-1
go.drugbank.com/bio_entities/BE0009396TargetHumansTransmembrane tyrosine-protein kinase that may modulate TEK/TIE2 activity and contribute to the regulation of angiogenesis
Polypeptides: Tyrosine-protein kinase receptor Tie-1Synonyms: TIETIR domain-containing adapter molecule 1
go.drugbank.com/bio_entities/BE0016552TargetHumansLigand binding to these receptors results in TRIF recruitment through its TIR domain (PubMed:12471095, PubMed:12539043, PubMed:14739303).
Polypeptides: TIR domain-containing adapter molecule 1Synonyms: Proline-rich, vinculin and TIR domain-containing protein B, TIR domain-containing adapter protein inducing IFN-betaImmunoglobulin heavy variable 3-23
go.drugbank.com/bio_entities/BE0004165TargetHumansV region of the variable domain of immunoglobulin heavy chains that participates in the antigen recognition (PubMed:24600447). Immunoglobulins, also known as antibodies, are membrane-bound or secreted glycoproteins produced by B lymphocy...
Synonyms: Ig heavy chain V-III region TILIgG heavy chain
go.drugbank.com/bio_entities/BE0010027TargetCarrierConstant region of immunoglobulin (Ig) heavy chains. Igs are membrane-bound or secreted glycoproteins produced by B lymphocytes. In the recognition phase of humoral immunity, the membrane-bound Igs serve as receptors, which upon binding ...
Synonyms: Ig gamma-2 chain C region TILElectrogenic aspartate/glutamate antiporter SLC25A12, mitochondrial
go.drugbank.com/bio_entities/BE0000235TargetHumansMitochondrial electrogenic aspartate/glutamate antiporter that favors efflux of aspartate and entry of glutamate and proton within the mitochondria as part of the malate-aspartate shuttle (PubMed:11566871, PubMed:19641205, PubMed:2451557...
Synonyms: AralarElectrogenic aspartate/glutamate antiporter SLC25A13, mitochondrial
go.drugbank.com/bio_entities/BE0000277TargetHumansMitochondrial electrogenic aspartate/glutamate antiporter that favors efflux of aspartate and entry of glutamate and proton within the mitochondria as part of the malate-aspartate shuttle (PubMed:11566871, PubMed:38937634, PubMed:3894528...
Synonyms: ARALAR-related gene 2Triosephosphate isomerase, glycosomal
go.drugbank.com/bio_entities/BE0001603TargetTrypanosoma cruziSynonyms: TIMTriosephosphate isomerase
go.drugbank.com/bio_entities/BE0001256TargetPlasmodium falciparumCatalyzes the interconversion of glyceraldehyde 3-phosphate and dihydroxyacetone phosphate in the glycolytic and gluconeogenic pathways.
Synonyms: TIM