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Displaying results 1 - 10 of 30 in total
  1. Target

    Bile salt-activated lipase

    go.drugbank.com/bio_entities/BE0004523
    TargetEnzymeHumans

    Catalyzes the hydrolysis of a wide range of substrates including cholesteryl esters, phospholipids, lysophospholipids, di- and tri-acylglycerols, and fatty acid esters of hydroxy fatty acids (FAHFAs) (PubMed:10220579, PubMed:27509211, Pu...

    Polypeptides: Bile salt-activated lipaseSynonyms: Bile salt-stimulated lipase
  2. Target

    Bile salt hydrolase/transferase

    go.drugbank.com/bio_entities/BE0001392
    TargetClostridium perfringens (strain 13 / Type A)

    Acts as a bile salt hydrolase that catalyzes the deconjugation of glycine- and taurine-linked bile salts, which occurs naturally in the intestines of humans, releasing amino acid residues and deconjugated

    Polypeptides: Bile salt hydrolase/transferaseSynonyms: Bile salt hydrolase
  3. Target

    Bifunctional PGK/TIM

    go.drugbank.com/bio_entities/BE0001611
    TargetThermotoga maritima (strain ATCC 43589 / MSB8 / DSM 3109 / JCM 10099)

    Polypeptides: Bifunctional PGK/TIMSynonyms: TIM
  4. Target

    Bile salt export pump

    go.drugbank.com/bio_entities/BE0000703
    TargetTransporterHumans

    Catalyzes the transport of the major hydrophobic bile salts, such as taurine and glycine-conjugated cholic acid across the canalicular membrane of hepatocytes in an ATP-dependent manner, therefore participates in hepatic bile acid homeos...

    Polypeptides: Bile salt export pump
  5. Target

    Immunoglobulin heavy constant gamma 2

    go.drugbank.com/bio_entities/BE0003805
    TargetHumans

    Constant region of immunoglobulin (Ig) heavy chains. Igs are membrane-bound or secreted glycoproteins produced by B lymphocytes. In the recognition phase of humoral immunity, the membrane-bound Igs serve as receptors, which upon binding ...

    Synonyms: Ig gamma-2 chain C region TIL
  6. Target

    Tyrosine-protein kinase receptor Tie-1

    go.drugbank.com/bio_entities/BE0009396
    TargetHumans

    Transmembrane tyrosine-protein kinase that may modulate TEK/TIE2 activity and contribute to the regulation of angiogenesis

    Polypeptides: Tyrosine-protein kinase receptor Tie-1Synonyms: TIE
  7. Target

    TIR domain-containing adapter molecule 1

    go.drugbank.com/bio_entities/BE0016552
    TargetHumans

    Ligand binding to these receptors results in TRIF recruitment through its TIR domain (PubMed:12471095, PubMed:12539043, PubMed:14739303).

    Polypeptides: TIR domain-containing adapter molecule 1Synonyms: Proline-rich, vinculin and TIR domain-containing protein B, TIR domain-containing adapter protein inducing IFN-beta
  8. Target

    FAD-linked sulfhydryl oxidase ALR

    go.drugbank.com/bio_entities/BE0004580
    TargetHumans

    FAD-dependent sulfhydryl oxidase that regenerates the redox-active disulfide bonds in CHCHD4/MIA40, a chaperone essential for disulfide bond formation and protein folding in the mitochondrial intermembrane space. The reduced form of CHCH...

    Synonyms: Augmenter of liver regeneration
  9. Target

    Immunoglobulin heavy variable 3-23

    go.drugbank.com/bio_entities/BE0004165
    TargetHumans

    V region of the variable domain of immunoglobulin heavy chains that participates in the antigen recognition (PubMed:24600447). Immunoglobulins, also known as antibodies, are membrane-bound or secreted glycoproteins produced by B lymphocy...

    Synonyms: Ig heavy chain V-III region TIL
  10. Target

    IgG heavy chain

    go.drugbank.com/bio_entities/BE0010027
    TargetCarrier

    Constant region of immunoglobulin (Ig) heavy chains. Igs are membrane-bound or secreted glycoproteins produced by B lymphocytes. In the recognition phase of humoral immunity, the membrane-bound Igs serve as receptors, which upon binding ...

    Synonyms: Ig gamma-2 chain C region TIL