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Displaying results 1 - 10 of 10000 in total
  1. Pathway

    Sialuria or French Type Sialuria

    smpdb.ca/view/SMP0000216
    Disease

    Sialuria is caused by mutation in the gene encoding uridinediphosphate-N-acetylglucosamine 2-epimerase (UDP-GlcNAc 2-epimerase, which causes an excessive synthesis of sialic acid (N-acetylneuraminic acid, NeuAc). This causes accumulation...

    Drugs: Pyruvic acid · L-Glutamine · N-Acetylglucosamine · Glutamic acid · ATP · Glucosamine +7 more
  2. Pathway

    Sialuria or French Type Sialuria

    smpdb.ca/view/SMP0000217
    Disease

    Sialuria is caused by mutation in the gene encoding uridinediphosphate-N-acetylglucosamine 2-epimerase (UDP-GlcNAc 2-epimerase, which causes an excessive synthesis of sialic acid (N-acetylneuraminic acid, NeuAc). This causes accumulation...

    Drugs: Pyruvic acid · L-Glutamine · N-Acetylglucosamine · Glutamic acid · ATP · Glucosamine +6 more
  3. Pathway

    Sialuria or French Type Sialuria

    smpdb.ca/view/SMP0125712
    Disease

    Sialuria is caused by mutation in the gene encoding uridinediphosphate-N-acetylglucosamine 2-epimerase (UDP-GlcNAc 2-epimerase, which causes an excessive synthesis of sialic acid (N-acetylneuraminic acid, NeuAc). This causes accumulation...

    Drugs: Pyruvic acid · L-Glutamine · N-Acetylglucosamine · Glutamic acid · ATP · Glucosamine +7 more
  4. Pathway

    Gemfibrozil Action Pathway

    smpdb.ca/view/SMP0125290
    Drug action

    Gemfibrozil is available in 600 mg oral tablets. The recommended dose for hypertriglyceridemia is 600 mg orally every 12 hours.

    Drugs: Biotin · Gemfibrozil · Magnesium cation
    Enzymes: Apolipoprotein B-100
  5. Pathway

    Fenofibrate Action Pathway

    smpdb.ca/view/SMP0125276
    Drug action

    Fenofibrate is a peroxisome proliferator receptor alpha activator used to treat primary hypercholesterolemia, mixed dyslipidemia, severe hypertriglyceridemia. Fenofibrate acts in the nucleus where is activates the peroxisome proliferator...

    Drugs: Biotin · Fenofibrate · Magnesium cation
    Enzymes: Apolipoprotein B-100
  6. Pathway

    Bezafibrate Action Pathway (New)

    smpdb.ca/view/SMP0125291
    Drug action

    Bezafibrate is a lipid-lowering fibrate used in the management of primary and secondary hyperlipidaemia, when there is a lack of clinical improvement following lifestyle modifications or correction of the underlying disorder. Bezafibrate...

    Drugs: Biotin · Magnesium cation · Bezafibrate
    Enzymes: Apolipoprotein B-100
  7. Pathway

    Acylcarnitine (10Z)-Pentadec-10-enoylcarnitine

    smpdb.ca/view/SMP0124228
    Metabolic

    (10Z)-Pentadec-10-enoylcarnitine is an acylcarnitine. … In forming an acylcarnitine derivative, (10Z)-pentadec-10-enoyl-CoA reacts with L-carnitine to form (10Z)-pentadec-10-enoylcarnitine. This reaction is catalyzed by carnitine O-palmitoyltransferase.

    Drugs: Biotin · Adenosine phosphate · ATP · Levocarnitine · Magnesium cation · Pyrophosphoric acid +1 more
  8. Pathway

    Acylcarnitine (10Z)-heptadec-10-enoylcarnitine

    smpdb.ca/view/SMP0124309
    Metabolic

    (10Z)-heptadec-10-enoylcarnitine is an acylcarnitine. … In forming an acylcarnitine derivative, (10Z)-heptadec-10-enoyl-CoA reacts with L-carnitine to form (10Z)-heptadec-10-enoylcarnitine. This reaction is catalyzed by carnitine O-palmitoyltransferase.

    Drugs: Biotin · Adenosine phosphate · ATP · Levocarnitine · Magnesium cation · Pyrophosphoric acid +1 more
  9. Pathway

    Acylcarnitine (10Z)-nonadec-10-enoylcarnitine

    smpdb.ca/view/SMP0124356
    Metabolic

    (10Z)-nonadec-10-enoylcarnitine is an acylcarnitine. … In forming an acylcarnitine derivative, (10Z)-nonadec-10-enoyl-CoA reacts with L-carnitine to form (10Z)-nonadec-10-enoylcarnitine. This reaction is catalyzed by carnitine O-palmitoyltransferase.

    Drugs: Biotin · Adenosine phosphate · ATP · Levocarnitine · Magnesium cation · Pyrophosphoric acid +1 more
  10. Pathway

    Acylcarnitine (10E)-8-Hydroxydodec-10-enoylcarnitine

    smpdb.ca/view/SMP0124017
    Metabolic

    (10E)-8-Hydroxydodec-10-enoylcarnitine is an acylcarnitine. … In forming an acylcarnitine derivative, (10E)-8-hydroxydodec-10-enoyl-CoA reacts with L-carnitine to form (10E)-8-hydroxydodec-10-enoylcarnitine.

    Drugs: Biotin · Adenosine phosphate · ATP · Levocarnitine · Magnesium cation · Pyrophosphoric acid +1 more