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Displaying results 1 - 10 of 60 in total
  1. Target

    Apolipoprotein E

    go.drugbank.com/bio_entities/BE0001119
    TargetCarrierHumans

    APOE is an apolipoprotein, a protein associating with lipid particles, that mainly functions in lipoprotein-mediated lipid transport between organs via the plasma and interstitial fluids (PubMed:14754908, PubMed:1911868, PubMed:6860692)....

    Polypeptides: Apolipoprotein ESynonyms: Apo-E
  2. Target

    Carboxypeptidase E

    go.drugbank.com/bio_entities/BE0001123
    EnzymeTargetHumans

    Sorting receptor that directs prohormones to the regulated secretory pathway. Also acts as a prohormone processing enzyme in neuro/endocrine cells, removing dibasic residues from the C-terminal end of peptide hormone precursors after ini...

    Polypeptides: Carboxypeptidase E
  3. Target

    Extended-spectrum beta-lactamase PER-1

    go.drugbank.com/bio_entities/BE0008647
    TargetPseudomonas aeruginosa

    Polypeptides: Extended-spectrum beta-lactamase PER-1
  4. Target

    E-selectin

    go.drugbank.com/bio_entities/BE0001074
    TargetHumans

    Cell-surface glycoprotein having a role in immunoadhesion. Mediates in the adhesion of blood neutrophils in cytokine-activated endothelium through interaction with SELPLG/PSGL1. May have a role in capillary morphogenesis

    Polypeptides: E-selectinSynonyms: CD62 antigen-like family member E
  5. Target

    Endoglucanase E-4

    go.drugbank.com/bio_entities/BE0003251
    TargetThermomonospora fusca

    Polypeptides: Endoglucanase E-4Synonyms: Cellulase E-4, Endo-1,4-beta-glucanase E-4
  6. Target

    Prostaglandin E synthase

    go.drugbank.com/bio_entities/BE0011075
    TargetHumans

    Terminal enzyme of the cyclooxygenase (COX)-2-mediated prostaglandin E2 (PGE2) biosynthetic pathway. Catalyzes the glutathione-dependent oxidoreduction of prostaglandin endoperoxide H2 (PGH2) to prostaglandin E2 (PGE2) in response to inf...

    Polypeptides: Prostaglandin E synthaseSynonyms: Microsomal prostaglandin E synthase 1
  7. Target

    Prostaglandin E synthase 3

    go.drugbank.com/bio_entities/BE0002480
    TargetHumans

    Cytosolic prostaglandin synthase that catalyzes the oxidoreduction of prostaglandin endoperoxide H2 (PGH2) to prostaglandin E2 (PGE2) (PubMed:10922363). Molecular chaperone that localizes to genomic response elements in a hormone-depende...

    Polypeptides: Prostaglandin E synthase 3
  8. Target

    Centromere-associated protein E

    go.drugbank.com/bio_entities/BE0003434
    TargetHumans

    Microtubule plus-end-directed kinetochore motor which plays an important role in chromosome congression, microtubule-kinetochore conjugation and spindle assembly checkpoint activation. Drives chromosome congression (alignment of chromoso...

    Polypeptides: Centromere-associated protein ESynonyms: CENP-E, Centromere protein E
  9. Target

    Botulinum neurotoxin type E

    go.drugbank.com/bio_entities/BE0009355
    TargetClostridium botulinum

    BoNT/E is a 'coincidence detector'; it requires simultaneous binding to coreceptor GT1b and low pH to transform into a membrane-bound, oligomeric channel (PubMed:22720883). … Precursor of botulinum neurotoxin E which has 2 coreceptors; complex polysialylated gangliosides found on neural tissue and specific membrane-anchored proteins found in synaptic vesicles.

    Polypeptides: Botulinum neurotoxin type ESynonyms: BoNT/E, Bontoxilysin-E
  10. Target

    Interleukin-17 receptor E

    go.drugbank.com/bio_entities/BE0017393
    TargetHumans

    Specific functional receptor for IL17C. May be signaling through the NF-kappa-B and MAPK pathways. May require TRAF3IP2 /ACT1 for signaling. May be a crucial regulator in innate immunity to bacterial pathogens. Isoform 2 and isoform 4 ma...

    Polypeptides: Interleukin-17 receptor ESynonyms: IL-17 receptor E