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Verapamil Action Pathway
smpdb.ca/view/SMP0000375Drug actionVerapamilÈs effects on pacemaker cells enable its use as a rate-controlling agent in atrial fibrillation. … Due to its cardioselective properties, verapamil may be used to treat arrhythmias (e.g. atrial fibrillation) as well as hypertension.
Enzymes: Potassium voltage-gated channel subfamily E member 1, Potassium voltage-gated channel subfamily E member 2Verapamil Calcium Channel Vasodilation Action Pathway
smpdb.ca/view/SMP0126373Drug actionVerapamil acts on smooth muscles and cardiac muscles. Verapamil is an L-type calcium channel blocker with antiarrhythmic, antianginal, and antihypertensive activity. … Verapamil, known as the brand names Calan, Isoptin, Tarka, and Verelan, is a non-dihydropyridine calcium channel blocker used in the treatment of angina, arrhythmia, and hypertension.
Verapamil Calcium Channel Cardiac Muscle Relaxation Action Pathway
smpdb.ca/view/SMP0126428Drug actionVerapamil acts on smooth muscles and cardiac muscles. … Verapamil, known as the brand names Calan, Isoptin, Tarka, and Verelan, is a non-dihydropyridine calcium channel blocker used in the treatment of angina, arrhythmia, and hypertension.
Enzymes: Potassium voltage-gated channel subfamily E member 1, Potassium voltage-gated channel subfamily E member 2Suprofen NSAID Action Pathway
smpdb.ca/view/SMP0124582Drug actionProstaglandin H2 can either be converted into thromboxane A2 via thromboxane A synthase, prostacyclin/prostaglandin I2 via prostacyclin synthase or prostaglandin E2 via prostaglandin E synthase.
Enzymes: Prostaglandin E synthaseKetoprofen NSAID Action Pathway
smpdb.ca/view/SMP0124635Drug actionProstaglandin H2 can either be converted into thromboxane A2 via thromboxane A synthase, prostacyclin/prostaglandin I2 via prostacyclin synthase or prostaglandin E2 via prostaglandin E synthase.
Enzymes: Prostaglandin E synthaseCelecoxib Action Pathway (New)
smpdb.ca/view/SMP0126384Drug actionCelecoxib is a nonsteroidal anti-inflammatory drug (NSAID) used to treat osteoarthritis, rheumatoid arthritis, acute pain, and menstrual symptoms, and to reduce polyps in familial adenomatous polyposis. This drug is a selective cyclooxyg...
Enzymes: Prostaglandin E synthaseGlycol salicylate Action Pathway
smpdb.ca/view/SMP0126550Drug actionProstaglandin H2 can either be converted into thromboxane A2 via thromboxane A synthase, prostacyclin/prostaglandin I2 via prostacyclin synthase, or prostaglandin E2 via prostaglandin E synthase.
Drugs: Glutathione · Dinoprostone · Calcium · Mesoheme · Prostaglandin G2 · Arachidonic Acid +1 moreEnzymes: Prostaglandin E synthaseIcosapent Prostaglandin G/H synthase 1 and 2 anti-inflammatory Action Pathway
smpdb.ca/view/SMP0126557Drug actionIcosapent is an important polyunsaturated fatty acid (eicosapentaenoic acid (EPA)). It is mostly found in fish oils. A diet rich in this molecule can be used/started to lower elevated triglycerides level in patients who are hyperglycerid...
Enzymes: Prostaglandin E synthaseFish oil Prostaglandin G/H synthase 1 and 2 anti-inflammatory Action Pathway
smpdb.ca/view/SMP0126563Drug actionProstaglandin H2 can either be converted into thromboxane A2 via thromboxane A synthase, prostacyclin/prostaglandin I2 via prostacyclin synthase, or prostaglandin E2 via prostaglandin E synthase.
Enzymes: Prostaglandin E synthaseSalsalate Action Pathway (New)
smpdb.ca/view/SMP0126583Drug actionProstaglandin H2 can either be converted into thromboxane A2 via thromboxane A synthase, prostacyclin/prostaglandin I2 via prostacyclin synthase, or prostaglandin E2 via prostaglandin E synthase.
Enzymes: Prostaglandin E synthase