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Malate dehydrogenase
go.drugbank.com/bio_entities/BE0001267TargetChloroflexus aurantiacus (strain ATCC 29366 / DSM 635 / J-10-fl)Catalyzes the reversible oxidation of malate to oxaloacetate.
Polypeptides: Malate dehydrogenaseFunction: L-malate dehydrogenase activityMalate synthase G
go.drugbank.com/bio_entities/BE0001750TargetMycobacterium tuberculosisCatalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA.
Polypeptides: Malate synthase GMalate dehydrogenase
go.drugbank.com/bio_entities/BE0000056TargetEscherichia coli (strain K12)Catalyzes the reversible oxidation of malate to oxaloacetate.
Polypeptides: Malate dehydrogenaseFunction: L-malate dehydrogenase activityMalate dehydrogenase
go.drugbank.com/bio_entities/BE0001891TargetAquaspirillum arcticumCatalyzes the reversible oxidation of malate to oxaloacetate.
Polypeptides: Malate dehydrogenaseFunction: L-malate dehydrogenase activityMalate dehydrogenase, cytoplasmic
go.drugbank.com/bio_entities/BE0000589TargetHumansPlays essential roles in the malate-aspartate shuttle and the tricarboxylic acid cycle, important in mitochondrial NADH supply for oxidative phosphorylation (PubMed:31538237).
Polypeptides: Malate dehydrogenase, cytoplasmicSynonyms: Cytosolic malate dehydrogenaseMalate dehydrogenase, mitochondrial
go.drugbank.com/bio_entities/BE0000780TargetEnzymeHumansMitochondrial malate dehydrogenase that catalyzes the reversible conversion of malate to oxaloacetate using NAD(+) as a cofactor (PubMed:27989324). … Also participates in the malate-aspartate NADH shuttle, facilitating transfer of reducing equivalents between cytosol and mitochondria to maintain redox balance (NAD(+)/NADH homeostasis) and support metabolic
Polypeptides: Malate dehydrogenase, mitochondrialMalate synthase G
go.drugbank.com/bio_entities/BE0001216TargetEscherichia coli (strain K12)Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA.
Polypeptides: Malate synthase GD-3-phosphoglycerate dehydrogenase
go.drugbank.com/bio_entities/BE0000161TargetHumansAlso catalyzes the reversible oxidation of 2-hydroxyglutarate to 2-oxoglutarate and the reversible oxidation of (S)-malate to oxaloacetate
Synonyms: Malate dehydrogenaseSuccinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial
go.drugbank.com/bio_entities/BE0000176TargetEnzymeHumansSDH also oxidizes malate to the non-canonical enol form of oxaloacetate, enol-oxaloacetate (By similarity).
Synonyms: Malate dehydrogenase [quinone] flavoprotein subunitSuccinate dehydrogenase
go.drugbank.com/bio_entities/BE0010253EnzymeTargetHumansSDH also oxidizes malate to the non-canonical enol form of oxaloacetate, enol-oxaloacetate (By similarity). … SDH also oxidizes malate to the non-canonical enol form of oxaloacetate, enol-oxaloacetate (By similarity).
Synonyms: Malate dehydrogenase [quinone] cytochrome b small subunit, Malate dehydrogenase [quinone] flavoprotein subunit