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Displaying results 1 - 10 of 14 in total

DrugBest match

Aflibercept

go.drugbank.com/drugs/DB08885

ApprovedInvestigational

Aflibercept is a recombinant protein composed of the binding domains of two human vascular endothelial growth factor (VEGF) receptors, VEGFR1 and VEGFR2, fused with the Fc region of human immunoglobulin gamma 1 (IgG1). Structurally, Aflibercept is a dimeric glycoprotein with a protein molecular weight of 96.9 kilo D...

Pathway
VEGF Signaling
smpdb.ca/view/SMP0524112
Signaling
Inhibitors like Bevacizumab and Aflibercept block VEGF A, preventing its effects and inhibiting angiogenesis, making them useful in treating cancers and other diseases with abnormal blood vessel growth
Drugs: Bevacizumab · Nitric Oxide · Calcium · Mesoheme · Aflibercept
Enzymes: Aflibercept
Indication
Branch Retinal Vein Occlusion With Macular Edema
go.drugbank.com/conditions/DBCOND0078116
Drugs: Aflibercept
Indication
Macular Edema With Central Retinal Vein Occlusions
go.drugbank.com/conditions/DBCOND0063502
Drugs: Aflibercept
Indication
Myopic Choroidal Neovascularization
go.drugbank.com/conditions/DBCOND0042416
Drugs: Aflibercept · Ranibizumab
Indication
Retinopathy of Prematurity (ROP)
go.drugbank.com/conditions/DBCOND0046296
Drugs: Aflibercept · Ranibizumab
Indication
Diabetic Retinopathy (DR)
go.drugbank.com/conditions/DBCOND0118126
Drugs: Aflibercept · Ranibizumab
Indication
Macular Edema
go.drugbank.com/conditions/DBCOND0001204
Drugs: Aflibercept · Dexamethasone · Ranibizumab · Triamcinolone
Indication
Diabetic Macular Edema (DME)
go.drugbank.com/conditions/DBCOND0060562
Drugs: Aflibercept · Dexamethasone · Faricimab · Fluocinolone acetonide · Ranibizumab
Drug
Tabirafusp tedromer
go.drugbank.com/drugs/DB19340
Investigational
Tabirafusp tedromer is under investigation in clinical trial NCT06556368 (A Study to Evaluate the Efficacy and Safety of Tarcocimab Tedromer and Tabirafusp Tedromer Compared to Aflibercept in Participants