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Crisaborole
Crisaborole is a novel oxaborole approved by FDA on December 14, 2016 as Eucrisa, a topical treatment of for mild to moderate atopic dermatitis. This non-steroidal agent is efficacious in improving disease severity, reducing the risk of infection and reducing the signs and symptoms in patients 2 years old and older....
Crisaborole Drug Metabolism
smpdb.ca/view/SMP0130654MetabolicCrisaborole passes through the liver and is then excreted from the body mainly through the kidney. … Crisaborole is a drug that is not metabolized by the human body as determined by current research and biotransformer analysis.
Drugs: CrisaboroleApremilast
go.drugbank.com/drugs/DB05676ApprovedInvestigationalIt belongs to the same drug class as [Roflumilast] and [Crisaborole].[A181244,L7495] Initially approved in 2014, it is marketed by Celgene.
PF-07038124
go.drugbank.com/drugs/DB19143InvestigationalPF-07038124 is under investigation in clinical trial NCT05298033 (Study of Efficacy, Safety and Tolerability of Crisaborole and PF-07038124 With and Without NBUVB in Vitiligo).
Mild Atopic dermatitis
go.drugbank.com/conditions/DBCOND0025273Moderate Atopic dermatitis
go.drugbank.com/conditions/DBCOND0025271