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Displaying results 1 - 10 of 81 in total
  1. Drug

    Tamoxifen

    go.drugbank.com/drugs/DB00675
    ApprovedInvestigational

    [A1026] Tamoxifen was granted FDA approval on 30 December 1977.[L7799] … [A1025,L7799,L7802] Tamoxifen is used alone or as an adjuvant in these treatments.

    Synonyms: Tamoxifen, trans-TamoxifenInternational brands: Tamifen, Tamofen
  2. Pathway

    Tamoxifen Action Pathway

    smpdb.ca/view/SMP0000471
    Drug action

    Tamoxifen is a selective estrogen modulator (SERM) used in the treatment of estrogen-sensitive breast cancer. … Tamoxifen itself only has weak anti-estrogen effects and must be converted into more active metabolites to have therapeutic activity.

    Drugs: Tamoxifen · Mesoheme · Flavin adenine dinucleotide · Uridine-5'-Diphosphate · Formaldehyde
  3. Pathway

    Tamoxifen Metabolism Pathway

    smpdb.ca/view/SMP0000606
    Drug metabolism

    Tamoxifen is a selective estrogen modulator (SERM) used in the treatment of estrogen-sensitive breast cancer. … Tamoxifen itself only has weak anti-estrogen effects and must be converted into more active metabolites to have therapeutic activity.

    Drugs: Tamoxifen · Mesoheme · Flavin adenine dinucleotide · Uridine-5'-Diphosphate · Formaldehyde
  4. Pathway

    Tamoxifen Anti-Cancer Action Pathway

    smpdb.ca/view/SMP0124698
    Drug action

    Overdose of tamoxifen leads to acute neurotoxicity seen by tremors, hyperreflexia, unsteady gait, and dizziness. Tamoxifen is usually administered in an oral form in a tablet or solution form. … Tamoxifen is an anticancer drug that is a selective estrogen receptor modulator also known as a non-steroidal anti-estrogen.

    Drugs: Tamoxifen · Estradiol · Mesoheme · Flavin adenine dinucleotide · Uridine-5'-Diphosphate · Formaldehyde
  5. Indication

    Prior Tamoxifen Therapy

    go.drugbank.com/conditions/DBCOND0125919
    Drugs: Letrozole
    Synonyms: Prior Tamoxifen Therapy
  6. Indication

    Disease progression with tamoxifen therapy

    go.drugbank.com/conditions/DBCOND0100394
    Drugs: Anastrozole
    Synonyms: Disease progression with tamoxifen therapy
  7. Indication

    2-3 years of tamoxifen therapy

    go.drugbank.com/conditions/DBCOND0106205
    Drugs: Anastrozole · Exemestane
    Synonyms: 2-3 years of tamoxifen therapy
  8. Drug

    Medroxyprogesterone acetate

    go.drugbank.com/drugs/DB00603
    ApprovedInvestigational

    Medroxyprogesterone acetate (MPA) is a progesterone derivative that is more resistant to metabolism for improved pharmacokinetic properties. MPA can be use to treat secondary amenorrhea, endometrial hyperplasia, abnormal uterine bleeding...

    Mixtures: OBAT SUNTIK KB IIProducts: OBAT SUNTIK KB I, OBAT SUNTIK KB I TIGA BULANAN
  9. Drug

    Cinnarizine

    go.drugbank.com/drugs/DB00568
    ApprovedInvestigational

    First synthesized by Janssen Pharmaceuticals in 1955, cinnarizine is an anti-histaminic drug mainly used for the control of vestibular disorders and motion sickness. Cinnarizine is a specific calcium channel blocker that primarily works ...

    Products: K.B GYDING
  10. Drug

    Levonorgestrel

    go.drugbank.com/drugs/DB00367
    ApprovedInvestigational

    Levonorgestrel (LNG) is a synthetic progestogen similar to Progesterone used in contraception and hormone therapy. Also known as Plan B, it is used as a single agent in emergency contraception, and as a hormonal contraceptive released fr...

    Mixtures: PIL KB HARMONIS, PIL KB I KOMBINASIProducts: SUSUK KB I TIGA TAHUNAN, SUSUK KB II TIGA TAHUNAN