Displaying drugs 3251 - 3275 of 11972 in total
Alglucosidase alfa
Aglucosidase alfa consists of the human enzyme acid alpha-glucosidase (GAA) which is essential for the degradation of glygogen to glucose in lysosomes. It is encoded by the most predominant of nine observed haplotypes of this gene. Aglucosidase alfa is produced by recombinant DNA technology in a Chinese hamster ovary cell...
Approved
Matched Description: … Structurally, Alglucosidase alfa is a glycoprotein with a calculated mass of 98,008 daltons for the 883 ... Alglucosidase alfa degrades glycogen by catalyzing the hydrolysis of a-1,4- and a-1,6- glycosidic linkages ... Aglucosidase alfa is produced by recombinant DNA technology in a Chinese hamster ovary cell line. …
Artemisia annua pollen
Artemisia annua pollen is the pollen of the Artemisia annua plant. Artemisia annua pollen is mainly used in allergenic testing.
Approved
Polistes exclamans venom protein
Polistes exclamans venom protein is an extract of Polistes exclamans venom. Polistes exclamans venom protein is used in allergenic testing.
Approved
Butamben
Butamben is a local anesthetic in the form of n-butyl-p-aminobenzoate. Its structure corresponds to the standard molecule of a hydrophilic and hydrophobic domain separated by an intermediate ester found in most of the local anesthetics. Due to its very low water solubility, butamben is considered to be suitable only for...
Approved
Withdrawn
Matched Description: … Butamben is a local anesthetic in the form of n-butyl-p-aminobenzoate. ... [A27147] Its structure corresponds to the standard molecule of a hydrophilic and hydrophobic domain separated …
Cinnamaldehyde
Cinnamaldehyde is a naturally occurring flavonoid that gives the spice cinnamon its flavour and odour. It occurs naturally in the bark of cinnamon trees and other species of the genus Cinnamomum such as camphor and cassia.
Sensitivity to cinnamaldehyde may be identified with a clinical patch test.
Approved
Experimental
Matched Description: … Sensitivity to cinnamaldehyde may be identified with a clinical patch test. ... Cinnamaldehyde is a naturally occurring flavonoid that gives the spice cinnamon its flavour and odour …
Matched Categories: … Compounds used in a research, industrial, or household setting …
Matched Categories: … Compounds used in a research, industrial, or household setting …
Patisiran
Parisiran is a first in class short interfering RNA for the treatment of patients with polyneuropathy caused by hereditary transthyretin-mediated amyloidosis . It is marketed as Onpattro which is formulated as patisiran within a liposome envelope for better delivery to the liver, where transthyretin is produced. The approval for Onpattro...
Approved
Investigational
Matched Description: … Parisiran is a first in class short interfering RNA for the treatment of patients with polyneuropathy ... It is marketed as Onpattro which is formulated as patisiran within a liposome envelope for better delivery …
Matched Categories: … Compounds used in a research, industrial, or household setting …
Matched Categories: … Compounds used in a research, industrial, or household setting …
Chlorpromazine
The prototypical phenothiazine antipsychotic drug. Like the other drugs in this class, chlorpromazine's antipsychotic actions are thought to be due to long-term adaptation by the brain to blocking dopamine receptors. Chlorpromazine has several other actions and therapeutic uses, including as an antiemetic and in the treatment of intractable hiccup.
Approved
Investigational
Vet approved
Artemisia tridentata pollen
Artemisia tridentata pollen is the pollen of the Artemisia tridentata plant. Artemisia tridentata pollen is mainly used in allergenic testing.
Approved
Carboprost tromethamine
A nonsteroidal abortifacient agent that is effective in both the first and second trimesters of pregnancy.
Approved
Matched Iupac: … (5Z)-7-[(1R,2R,3R,5S)-3,5-dihydroxy-2-[(1E,3S)-3-hydroxy-3-methyloct-1-en-1-yl]cyclopentyl]hept-5-enoic …
Matched Description: … A nonsteroidal abortifacient agent that is effective in both the first and second trimesters of pregnancy …
Matched Description: … A nonsteroidal abortifacient agent that is effective in both the first and second trimesters of pregnancy …
Capreomycin
Cyclic peptide antibiotic similar to viomycin. It is produced by Streptomyces capreolus.
Approved
Matched Categories: … Drugs that are Mainly Renally Excreted with a Narrow Therapeutic Index …
Azilsartan medoxomil
Azilsartan medoxomil is a prodrug that is broken down to azilsartan, which belongs in the angiotensin-receptor blocking (ARB) drug class. It is a selective AT1 subtype angiotensin II receptor antagonist. Azilsartan medoxomil is a relatively recently-developed antihypertensive drug that was first approved by the FDA in February 2011. Many guidelines...
Approved
Investigational
Matched Description: … It is a selective AT1 subtype angiotensin II receptor antagonist. ... It is also available in a combination product with [chlorthalidone]. ... Azilsartan medoxomil is a prodrug that is broken down to azilsartan, which belongs in the angiotensin-receptor …
Populus deltoides subsp. monilifera pollen
Populus deltoides subsp. monilifera pollen is the pollen of the Populus deltoides subsp. monilifera plant. Populus deltoides subsp. monilifera pollen is mainly used in allergenic testing.
Approved
Technetium Tc-99m pyrophosphate
A radionuclide imaging agent used primarily in scintigraphy or tomography of the heart to evaluate the extent of the necrotic myocardial process. It has also been used in noninvasive tests for the distribution of organ involvement in different types of amyloidosis and for the evaluation of muscle necrosis in the...
Approved
Matched Description: … A radionuclide imaging agent used primarily in scintigraphy or tomography of the heart to evaluate the …
Matched Categories: … Compounds used in a research, industrial, or household setting …
Matched Categories: … Compounds used in a research, industrial, or household setting …
Radium Ra 223 dichloride
Radium Ra 223 Dichloride is a radiopharmaceutical containing the radioisotope radium-223 that emits short range but high linear energy alpha particles. As a cation, radium mimics calicum and binds to hydroxyapatite, which is a bone mineral found in areas of high bone turnover as seen in bone metastases. It was...
Approved
Investigational
Matched Description: … As a cation, radium mimics calicum and binds to hydroxyapatite, which is a bone mineral found in areas ... Radium Ra 223 Dichloride is a radiopharmaceutical containing the radioisotope radium-223 that emits short ... The FDA label includes a warning that Radium Ra 223 Dichloride should not be used in women who are pregnant …
Moxisylyte
Moxisylyte, denominated as thymoxamine in the UK, is a specific and orally active α1-adrenergic antagonist. According to the WHO, moxisylyte is approved since 1987 and in the same year, it acquired the denomination of orphan product by the FDA. This drug was developed by the Japanese company Fujirebio and also...
Approved
Investigational
Matched Description: … Moxisylyte, denominated as thymoxamine in the UK, is a specific and orally active α1-adrenergic antagonist …
Dequalinium
Dequalinium is an antibacterial agent with multi-targeted actions. It also possesses antifungal, antiparasitic, antiviral, anticancer, and neuroprotective properties. It is a quaternary ammonium compound, as it consists of an amphipathic cation with two aminoquinaldinium rings at both ends of a long hydrophobic hydrocarbon chain. Due to its flexible structure, dequalinium...
Approved
Investigational
Matched Description: … two aminoquinaldinium rings at both ends of a long hydrophobic hydrocarbon chain. ... [A249255] It is a quaternary ammonium compound,[L42190] as it consists of an amphipathic cation with …
Populus fremontii pollen
Populus fremontii pollen is the pollen of the Populus fremontii plant. Populus fremontii pollen is mainly used in allergenic testing.
Approved
Acacia baileyana pollen
Acacia baileyana pollen is the pollen of the Acacia baileyana plant. Acacia baileyana pollen is mainly used in allergenic testing.
Approved
Telaprevir
Telaprevir is a direct acting antiviral medication used as part of combination therapy to treat chronic Hepatitis C, an infectious liver disease caused by infection with Hepatitis C Virus (HCV). HCV is a single-stranded RNA virus that is categorized into nine distinct genotypes, with genotype 1 being the most common...
Approved
Withdrawn
Matched Description: … Telaprevir is a direct acting antiviral medication used as part of combination therapy to treat chronic ... HCV is a single-stranded RNA virus that is categorized into nine distinct genotypes, with genotype 1 ... Telaprevir is an inhibitor of NS3/4A, a serine protease enzyme, encoded by HCV genotype 1 [FDA Label] …
Gadofosveset trisodium
Gadofosveset trisodium is an intravenous contrast agent used with magnetic resonance angiography(MRA), which is a non-invasive way of imaging blood vessels. The agent allows for the vascular system to be imaged more clearly by the MRA. In this way, gadofosveset trisodium is used to help diagnose certain disorders of the...
Approved
Matched Description: … trisodium is an intravenous contrast agent used with magnetic resonance angiography(MRA), which is a …
Matched Categories: … Compounds used in a research, industrial, or household setting …
Matched Categories: … Compounds used in a research, industrial, or household setting …
Brentuximab vedotin
Brentuximab vedotin, also known as Adcetris®, is an antibody-drug conjugate that combines an anti-CD30 antibody with the drug monomethyl auristatin E (MMAE). It is an anti-neoplastic agent used in the treatment of Hodgkin's lymphoma and systemic anaplastic large-cell lymphoma. Brentuximab vedotin was initially approved in 2011. In January 2012, the...
Approved
Investigational
Matched Description: … In January 2012, the drug label was revised with a boxed warning of a condition known as progressive ... Importantly, bleomycin - a highly toxic agent - was completely removed from the regimen. ... to treat Hodgkin's lymphoma after relapse, Hodgkin's lymphoma after stem cell transplantation when a …
Matched Categories: … P-glycoprotein substrates with a Narrow Therapeutic Index ... Cytochrome P-450 CYP3A4 Substrates with a Narrow Therapeutic Index …
Matched Categories: … P-glycoprotein substrates with a Narrow Therapeutic Index ... Cytochrome P-450 CYP3A4 Substrates with a Narrow Therapeutic Index …
Thiram
Thiram may be used in dermatology as a scabicide . Thiram is mainly used as a fungicide for plants and treatment for seeds, however, this use is being investigated for safety in many markets including Canada .
Approved
Experimental
Matched Description: … Thiram may be used in dermatology as a scabicide [T436]. ... Thiram is mainly used as a fungicide for plants and treatment for seeds, however, this use is being investigated …
Matched Categories: … Compounds used in a research, industrial, or household setting …
Matched Categories: … Compounds used in a research, industrial, or household setting …
Dibekacin
Dibekacin is an aminoglycoside antibiotic marketed in Japan .
Approved
Matched Categories: … Drugs that are Mainly Renally Excreted with a Narrow Therapeutic Index …
Gadodiamide
Gadodiamide is a linear, non-ionic gadolinium-based contrast agent (GBCA) that is used in magnetic resonance imaging (MRI) procedures to assist in the visualization of blood vessels.[A263086,A263091] GBCAs constitute the largest group of MR agents, and they are thought to be safer than nonionic iodinated contrast agents. Approved by the FDA...
Approved
Investigational
Matched Description: … Gadodiamide is a linear, non-ionic gadolinium-based contrast agent (GBCA) that is used in magnetic resonance …
Matched Categories: … Compounds used in a research, industrial, or household setting …
Matched Categories: … Compounds used in a research, industrial, or household setting …
Displaying drugs 3251 - 3275 of 11972 in total