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Displaying drugs 3301 - 3325 of 11972 in total

Mannitol

Mannitol is an osmotic diuretic that is metabolically inert in humans and occurs naturally, as a sugar or sugar alcohol, in fruits and vegetables. Mannitol elevates blood plasma osmolality, resulting in enhanced flow of water from tissues, including the brain and cerebrospinal fluid, into interstitial fluid and plasma. As a...
Approved
Investigational
Matched International brands: … Mannisol A …
Matched Description: … Mannitol is an osmotic diuretic that is metabolically inert in humans and occurs naturally, as a sugar ... As a result, cerebral edema, elevated intracranial pressure, and cerebrospinal fluid volume and pressure ... established; the promotion of urinary excretion of toxic substances; as an Antiglaucoma agent; and as a …
Matched Categories: … Compounds used in a research, industrial, or household setting …

Cangrelor

Cangrelor is an intravenous, direct-acting, reversible P2Y12 inhibitor for patients undergoing percutaneous coronary intervention (PCI) who have not been yet treated by oral P2Y12 inhibitors. An advantage Cangrelor provides over oral P2Y12 inhibitors (such as prasugrel, ticagrelor, and clopidogrel) is that it is an active drug not requiring metabolic conversion...
Approved
Matched Description: … and clopidogrel) is that it is an active drug not requiring metabolic conversion therefore providing a …

Inositol nicotinate

Inositol nicotinate, also known as Inositol hexaniacinate/hexanicotinate or "no-flush niacin", is a niacin ester and vasodilator. It is used in food supplements as a source of niacin (vitamin B3), where hydrolysis of 1 g (1.23 mmol) inositol hexanicotinate yields 0.91 g nicotinic acid and 0.22 g inositol. Niacin exists in...
Approved
Withdrawn
Matched Description: … Inositol nicotinate, also known as Inositol hexaniacinate/hexanicotinate or "no-flush niacin", is a niacin ... It is used in food supplements as a source of niacin (vitamin B3), where hydrolysis of 1 g (1.23 mmol ... Inositol nicotinate is prescribed in Europe under the name Hexopal as a symptomatic treatment for severe …

Peginterferon alfa-2a

Peginterferon alfa-2a is a form of recombinant interferon used as part of combination therapy to treat chronic Hepatitis C, an infectious liver disease caused by infection with Hepatitis C Virus (HCV). HCV is a single-stranded RNA virus that is categorized into nine distinct genotypes, with genotype 1 being the most...
Approved
Investigational
Matched Description: … Peginterferon alfa-2a is a form of recombinant interferon used as part of combination therapy to treat ... HCV is a single-stranded RNA virus that is categorized into nine distinct genotypes, with genotype 1 ... Use of Peginterferon alfa-2a is associated with a wide range of severe adverse effects including the …
Matched Categories: … Compounds used in a research, industrial, or household setting …

Haemophilus influenzae b polysaccharide-tetanus conjugate

Approved

Indinavir

A potent and specific HIV protease inhibitor that appears to have good oral bioavailability. [PubChem]
Approved
Matched Description: … A potent and specific HIV protease inhibitor that appears to have good oral bioavailability. …

Oxcarbazepine

Oxcarbazepine is an anti-epileptic medication used in the treatment of partial onset seizures that was first approved for use in the United States in 2000.[L8627,L8630,L8633] It is a structural derivative of carbamazepine and exerts a majority of its activity via a pharmacologically active metabolite, MHD, which exists as a racemate...
Approved
Matched Description: … [L8627,L8630,L8633] It is a structural derivative of [carbamazepine][A186101] and exerts a majority of ... its activity via a pharmacologically active metabolite, MHD, which exists as a racemate in the blood ... - a pro-drug of the more active (S)-enantiomer is also marketed as a separate anti-epileptic under the …

Diatrizoate

A commonly used x-ray contrast medium. As diatrizoate meglumine and as Diatrizoate sodium, it is used for gastrointestinal studies, angiography, and urography.
Approved
Vet approved
Matched Description: … A commonly used x-ray contrast medium. …
Matched Categories: … Compounds used in a research, industrial, or household setting …

Chlorthalidone

Chlorthalidone is a thiazide-like diuretic used for the treatment of hypertension and for management of edema caused by conditions such as heart failure or renal impairment. Chlorthalidone improves blood pressure and swelling by preventing water absorption from the kidneys through inhibition of the Na+/Cl− symporter in the distal convoluted tubule...
Approved
Matched Description: … Chlorthalidone is a thiazide-like diuretic used for the treatment of hypertension and for management ... These pathways may play a role in chlorthalidone's cardiovascular risk reduction effects.[A176330] ... Chlorthalidone has been shown to have a number of pleiotropic effects that differentiate it from other …
Matched Mixtures name: … ATENOLOL CO RATIO 100/25MG …

Delamanid

Delamanid is an anti-tuberculosis agent derived from the nitro-dihydro-imidazooxazole class of compounds that inhibits mycolic acid synthesis of bacterial cell wall . It is used in the treatment of multidrug-resistant and extensively drug-resistant tuberculosis (TB) in a combination regimen. Emergence of multidrug-resistant and extensively drug-resistant tuberculosis creates clinical challenges for...
Approved
Investigational
Matched Description: … It is marketed by Otsuka Pharmaceutical Co., Ltd (Tokyo, Japan). ... is used in the treatment of multidrug-resistant and extensively drug-resistant tuberculosis (TB) in a ... In a clinical study involving patients with pulmonary multidrug-resistant tuberculosis or extensively …

Thiabendazole

2-Substituted benzimidazole first introduced in 1962. It is active against a variety of nematodes and is the drug of choice for strongyloidiasis. It has CNS side effects and hepatototoxic potential. (From Smith and Reynard, Textbook of Pharmacology, 1992, p919)
Approved
Vet approved
Matched Description: … It is active against a variety of nematodes and is the drug of choice for strongyloidiasis. …

Ticagrelor

Ticagrelor, or AZD6140, was first described in the literature in 2003.[A204170,A2903] Ticagrelor is an ADP derivative developed for its P2Y12 receptor antagonism. Unlike clopidogrel, ticagrelor is not a prodrug. It is marketed by Astra Zeneca as Brilinta in the US and Brilique or Possia in the EU, . Ticagrelor was...
Approved
Matched Description: … [A2903] Unlike [clopidogrel], ticagrelor is not a prodrug. …

Eucalyptus oil

Eucalyptus oil is a distilled oil derived from the leaves of the tree Eucalyptus. It is shown to be effective in reducing pain, swelling, and inflammation via its modulatory effect on the immune response. It is also shown to exhibit antibacterial activity against some bacterial species and cough suppressant actions....
Approved
Matched Description: … Eucalyptus oil is a distilled oil derived from the leaves of the tree Eucalyptus. …
Matched Mixtures name: … Antiphlogistine Rub A 535 Extra Strength …

Mangafodipir

Mangafodipir is a contrast agent used as a diagnostic tool administered intravenously to enhance contrast in magnetic resonance imaging (MRI) of the liver and pancreas. This drug is made up of paramagnetic manganese (II) ions combined with the chelating agent fodipir (dipyridoxyl diphosphate, DPDP). Manganese absorption into the tissues that...
Approved
Investigational
Withdrawn
Matched Description: … Mangafodipir is a contrast agent used as a diagnostic tool administered intravenously to enhance contrast …
Matched Categories: … Compounds used in a research, industrial, or household setting …

Sonidegib

Sonidegib is a Hedgehog signaling pathway inhibitor (via smoothened antagonism) developed as an anticancer agent by Novartis. It was FDA approved in 2015 for the treatment of basal cell carcinoma.
Approved
Investigational
Matched Description: … Sonidegib is a Hedgehog signaling pathway inhibitor (via smoothened antagonism) developed as an anticancer …
Matched Categories: … Cytochrome P-450 CYP3A4 Substrates with a Narrow Therapeutic Index …

Ioversol

Ioversol is a non-ionic compound with a tri-iodinated benzene ring used as a contrast dye in diagnostic procedures to visualize different types of organs and tissues. Iodine has a high atomic density, which gives it the ability to attenuate X-rays. The intravascular administration of iodine compounds, such as ioversol, enhances...
Approved
Matched Description: … Ioversol is a non-ionic compound with a tri-iodinated benzene ring used as a contrast dye in diagnostic ... [L41780] Iodine has a high atomic density, which gives it the ability to attenuate X-rays. ... [L41780] Ioversol is a highly hydrophilic agent considered to be generally safe[L41790]; however, serious …
Matched Categories: … Compounds used in a research, industrial, or household setting …

Benperidol

Benperidol has been used in trials studying the treatment of Dementia, Depression, Schizophrenia, Anxiety Disorders, and Psychosomatic Disorders, among others.
Approved
Investigational

Doxapram

A central respiratory stimulant with a brief duration of action. (From Martindale, The Extra Pharmocopoeia, 30th ed, p1225)
Approved
Vet approved
Matched Description: … A central respiratory stimulant with a brief duration of action. …

Crotalus atrox antivenin

Each year it is estimated there are 45,000 snakebites in the US and 300,000 to 400,000 bites worldwide. About 8000 of these snakebites involve venomous snake species. The majority of people bitten are males and about 50% occur in the age group of 18 to 28 . Crotalus atrox antivenin...
Approved
Experimental

Hydrocodone

Hydrocodone is a synthetic opioid derivative of codeine. It is commonly used in combination with acetaminophen to control moderate to severe pain. Historically, hydrocodone has been used as a cough suppressant although this has largely been replaced by dextromethorphan in current cough and cold formulations. Hydrocodone's more potent metabolite, hydromorphone...
Approved
Illicit
Investigational
Matched Description: … Hydrocodone is a synthetic opioid derivative of codeine. ... Historically, hydrocodone has been used as a cough suppressant although this has largely been replaced …
Matched Mixtures name: … Co-gesic …

Blinatumomab

Blinatumomab is a BiTE-class (bi-specific T-cell engager) constructed monoclonal antibody formed by the recombinant fusion of an anti-CD3 single-chain variable fragment (scFV) and an anti-CD19 scFV through a short peptide linker.[A254836,L44311] CD3 is an antigen expressed on the surface of T-cells, while CD19 is mostly expressed on the surface of...
Approved
Investigational
Matched Description: … [L46991,L46996] Blinatumomab has a short half-life, requiring patients to receive a continuous infusion ... over 4-week cycles using a portable mini-pump for optimum delivery. ... Blinatumomab is a BiTE-class (bi-specific T-cell engager) constructed monoclonal antibody formed by the …

Gemfibrozil

Gemfibrozil is a fibric acid agent, similar to clofibrate, used to treat Type IIb, IV, and V hyperlipidemias.[A185777,L8525] Gemfibrozil is not a first line treatment and is prescribed to patients who have not responded adequately to weight loss, diet, exercise, and other medications. Gemfibrozil was granted FDA approval on 21...
Approved
Matched Description: … [A185777,L8525] Gemfibrozil is not a first line treatment and is prescribed to patients who have not ... Gemfibrozil is a fibric acid agent, similar to [clofibrate], used to treat Type IIb, IV, and V hyperlipidemias …

Tozinameran

The Pfizer-BioNTech COVID-19 vaccine (also known as BNT162b2, Tozinameran, and Comirnaty), is one of four advanced mRNA-based vaccines developed through "Project Lightspeed," a joint program between Pfizer and BioNTech.[L15002,L15007,L36025] Comirnaty is a nucleoside modified mRNA (modRNA) vaccine encoding an optimized full-length version of the severe acute respiratory syndrome coronavirus 2...
Approved
Investigational
Matched Description: … similar safety profile to other viral vaccines over a span of approximately 2 months. ... and Comirnaty), is one of four advanced mRNA-based vaccines developed through "Project Lightspeed," a ... [L15002,L15007,L36025] Comirnaty is a nucleoside modified mRNA (modRNA) vaccine encoding an optimized …

Oxandrolone

A synthetic hormone with anabolic and androgenic properties.
Approved
Investigational
Matched Description: … A synthetic hormone with anabolic and androgenic properties. …

Flucytosine

A fluorinated cytosine analog that is used as an antifungal agent.
Approved
Investigational
Matched Description: … A fluorinated cytosine analog that is used as an antifungal agent. …
Displaying drugs 3301 - 3325 of 11972 in total