Displaying drugs 4426 - 4450 of 11348 in total
LB-001
LB-001 is a gene editing therapy designed to incorporate a functioning version of the faulty methylmalonyl-COA mutase (MUT) gene into the genome of patients with methylmalonic acidemia.
Investigational
Matched Description: … LB-001 is a gene editing therapy designed to incorporate a functioning version of the faulty methylmalonyl-COA …
Giroctocogene fitelparvovec
Giroctocogene fitelparvovec is under investigation in clinical trial NCT04370054 (Study to Evaluate the Efficacy and Safety of PF-07055480 in Moderately Severe to Severe Hemophilia a Adults).
Investigational
Matched Description: … (Study to Evaluate the Efficacy and Safety of PF-07055480 in Moderately Severe to Severe Hemophilia a …
P140K methylguanine-DNA-methyltransferase mutant CD34+ cells
Investigational
CDP323
CDP323 is an antagonist of the vascular cell adhesion molecule 1 (VCAM-1) binding to alpha4-integrins (other adhesion molecules), a process thought to be implicated in the pathophysiology of Multiple Sclerosis (MS). It is considered a small-molecule prodrug. CDP323 was originally developed by the British biopharmaceutical company Celltech plc. (now UCB...
Investigational
Matched Description: … It is considered a small-molecule prodrug. ... (now UCB S.A.) and is a putative new drug for oral treatment of multiple sclerosis. ... vascular cell adhesion molecule 1_ (VCAM-1) binding to alpha4-integrins (other adhesion molecules), a …
CD8+ enriched young tumor infiltrating lymphocytes
Investigational
Batroxobin
Batroxobin is a defibrinogenating hemostatic agent derived from the venom of a pit viper, Bothrops atrox moojeni. In addition to batroxobin, the venom of Bothrops atrox has a composition of 10.2% neutral carbohydrate. Batroxobin is a serine protease, which cleaves the 16 Arginine - 17 Glycine bond in fibrinogen. The...
Experimental
Matched Description: … Batroxobin is a defibrinogenating hemostatic agent derived from the venom of a pit viper, Bothrops atrox ... Batroxobin will also bind fibrinogen in a manner different than thrombin and with a higher affinity. ... Batroxobin is a serine protease, which cleaves the 16 Arginine - 17 Glycine bond in fibrinogen. …
Matched Categories: … Venombin A …
Matched Categories: … Venombin A …
AG-702
AG-702 is a recombinant human heat shock protein also known as stress protein. It is also known as HSPs, which are a group of proteins that are induced when a cell undergoes various types of environmental stresses like heat, cold and oxygen deprivation. HSPs are present in all cells in...
Investigational
Matched Description: … AG-702 is a recombinant human heat shock protein also known as stress protein. ... It is also known as HSPs, which are a group of proteins that are induced when a cell undergoes various ... types of environmental stresses like heat, cold and oxygen deprivation. …
Recombinant soluble human CD4
Investigational
CEP-1347
CEP-1347 is a semi-synthetic compound shown to protect multiple nerve cell types from a variety of insults leading to programmed cell death (apoptosis) which could improve the survival of dopamine neurons prior to and after transplantation.
Investigational
Matched Description: … CEP-1347 is a semi-synthetic compound shown to protect multiple nerve cell types from a variety of insults …
NeuroCell-PD
Investigational
Recombinant human CD4 immunoglobulin G
Investigational
Xylitol
Xylitol is a naturally occurring five-carbon sugar alcohol found in most plant material, including many fruits and vegetables. Xylitol-rich plant materials include birch and beechwood . It is widely used as a sugar substitute and in "sugar-free" food products. The effects of xylitol on dental caries have been widely studied,...
Experimental
Investigational
Matched Description: … It is widely used as a sugar substitute and in "sugar-free" food products. ... Xylitol is a naturally occurring five-carbon sugar alcohol found in most plant material, including many ... Xylitol is a non-fermentable sugar alcohol by most plaque bacteria, indicating that it cannot be fermented …
Matched Mixtures name: … Fluor-a-day ... Fluor-a-day ... Fluor-a-day …
Matched Categories: … Compounds used in a research, industrial, or household setting …
Matched Mixtures name: … Fluor-a-day ... Fluor-a-day ... Fluor-a-day …
Matched Categories: … Compounds used in a research, industrial, or household setting …
Theralizumab
Theralizumab is a humanized anti-CD28 monoclonal antibody designed for treating autoimmune diseases and cancer. After the first human trial, it was withdrawn due to severe toxicity (likely due to lymphopenia and human cytokine release).[A216527,A216532]
Investigational
Matched Description: … Theralizumab is a humanized anti-CD28 monoclonal antibody designed for treating autoimmune diseases and …
Dimiracetam
Dimiracetam has been used in trials studying the treatment of AIDS, Neuropathy, and Acquired Immunodeficiency Syndrome.
Investigational
Matched Iupac: … hexahydro-1H-pyrrolo[1,2-a]imidazole-2,5-dione …
Tea tree oil
Tea tree oil is an essential oil derived mainly from the Australian native plant Melaleuca alternifolia via steam distillation of the of the leaves and terminal branches . It may be referred to as Melaleuca alternifolia oil. It has been a popular ingredient in a variety of household and cosmetic...
Experimental
Nutraceutical
Matched Description: … It has been a popular ingredient in a variety of household and cosmetic products due to its antiseptic …
Matched Mixtures name: … Muscle and Joint Heat Cream …
Matched Mixtures name: … Muscle and Joint Heat Cream …
Clomethiazole
Clomethiazole is a well-established γ-aminobutyric acid (GABAA)-mimetic drug. It is a sedative and hypnotic that is widely used in treating and preventing symptoms of acute alcohol withdrawal. It is a drug which is structurally related to thiamine (vitamin B1) but acts like a sedative, hypnotic, muscle relaxant and anticonvulsant. It...
Investigational
Matched Description: … It is a drug which is structurally related to thiamine (vitamin B1) but acts like a sedative, hypnotic ... Clomethiazole is a well-established γ-aminobutyric acid (GABAA)-mimetic drug. ... It is a sedative and hypnotic that is widely used in treating and preventing symptoms of acute alcohol …
Matched Categories: … Compounds used in a research, industrial, or household setting …
Matched Categories: … Compounds used in a research, industrial, or household setting …
Taniraleucel
Investigational
Aloe vera leaf
Aloe describes a genus including over 500 species of flowering succulent plants that grow in the Southern peninsula and various islands. Aloe vera, or Aloe barbadensis miller, is the most common species of Aloe that is cultivated for agricultural and medical purposes. It is a perennial succulent xerophyte with elongated...
Experimental
Matched Description: … It is a perennial succulent xerophyte with elongated leaves that contain a clear gel. ... Aloe describes a genus including over 500 species of flowering succulent plants that grow in the Southern ... While aloe vera has a long history of commercial uses, it is still widely used in cosmetic, food and …
Matched Mixtures name: … Alcortin A ... Alcortin A …
Matched Mixtures name: … Alcortin A ... Alcortin A …
Dibromothymoquinone
At low concentrations, this compound inhibits reduction of conventional hydrophilic electron acceptors, probably acting as a plastoquinone antagonist. At higher concentrations, it acts as an electron acceptor, intercepting electrons either before or at the site of its inhibitory activity. [PubChem]
Experimental
Matched Description: … this compound inhibits reduction of conventional hydrophilic electron acceptors, probably acting as a …
Carotuximab
Investigational
mRNA-3705
mRNA-3705 is an investigational mRNA encoding methylmalonic CoA mutase (MUT) enzyme. Developed by Moderna TX Inc., it is being investigated for the treatment of methylmalonic academia.
Investigational
Matched Description: … mRNA-3705 is an investigational mRNA encoding methylmalonic CoA mutase (MUT) enzyme. …
Displaying drugs 4426 - 4450 of 11348 in total