Displaying drugs 476 - 500 of 11608 in total
Avalglucosidase alfa
Avalglucosidase alfa, or NeoGAA, is a drug for enzyme replacement therapy specifically designed for Pompe disease, a rare inherited neuromuscular disorder caused by the deficiency of the alpha-glucosidase (GAA) enzyme. GAA is an essential enzyme that hydrolyzes glycogen into free glucose for use in cellular functions. In Pompe disease, the...
Approved
Investigational
Matched Description: … Avalglucosidase alfa, or NeoGAA, is a drug for enzyme replacement therapy specifically designed for Pompe ... disease, a rare inherited neuromuscular disorder caused by the deficiency of the alpha-glucosidase ( ... [A232955] Avalglucosidase alfa is a recombinant form of GAA that restores deficient enzyme levels. …
Lovastatin
Lovastatin, also known as the brand name product Mevacor, is a lipid-lowering drug and fungal metabolite derived synthetically from a fermentation product of Aspergillus terreus. Originally named Mevinolin, lovastatin belongs to the statin class of medications, which are used to lower the risk of cardiovascular disease and manage abnormal lipid...
Approved
Investigational
Matched Description: … derived synthetically from a fermentation product of _Aspergillus terreus_. ... Lovastatin, also known as the brand name product Mevacor, is a lipid-lowering drug and fungal metabolite ... leading cause of death in high-income countries and a major cause of morbidity around the world. …
Viloxazine
Viloxazine is a selective norepinephrine reuptake inhibitor. For decades, an immediate-release formulation of viloxazine has been used in Europe as an antidepressant. It was first approved in the UK in 1974; however, the immediate-release formulation was discontinued due to business reasons unrelated to drug safety and efficacy. In the US,...
Approved
Investigational
Withdrawn
Matched Description: … Viloxazine is a selective norepinephrine reuptake inhibitor. …
Matched Categories: … Monoamine Oxidase A Inhibitors for interaction with Monoamine Oxidase A substrates ... Monoamine Oxidase A Inhibitors …
Matched Categories: … Monoamine Oxidase A Inhibitors for interaction with Monoamine Oxidase A substrates ... Monoamine Oxidase A Inhibitors …
Phenoxyethanol
Phenoxyethanol is a colorless liquid with a pleasant odor. It is a glycol ether used as a perfume fixative, insect repellent, antiseptic, solvent, preservative, and also as an anesthetic in fish aquaculture. Phenoxyethanol is an ether alcohol with aromatic properties. It is both naturally found and manufactured synthetically. Demonstrating antimicrobial...
Approved
Matched Description: … Phenoxyethanol is a colorless liquid with a pleasant odor. ... It is a glycol ether used as a perfume fixative, insect repellent, antiseptic, solvent, preservative, ... Phenoxyethanol is a colorless, clear, oily liquid with a faint aromatic odor at room temperature and …
Salmeterol
Salmeterol is a long-acting beta-2 adrenergic receptor agonist drug that is currently prescribed for the treatment of asthma and chronic obstructive pulmonary disease COPD.[L11545,L11548,L11551,L11554,L11557] It has a longer duration of action than the short-acting beta-2 adrenergic receptor agonist, salbutamol. Salmeterol was first described in the literature in 1988. Salmeterol's structure...
Approved
Matched Description: … Salmeterol is a long-acting beta-2 adrenergic receptor agonist drug that is currently prescribed for ... [L11545,L11548,L11551,L11554,L11557] It has a longer duration of action than the short-acting beta-2 …
Emicizumab
Emicizumab is a humanized recombinant monoclonal antibody that mimics the function of the coagulation Factor VIII and it has the capacity to bind simultaneously to activated Factor IX and Factor X. The ability of Emicizumab to bind to all these three different factors allows it to overcome immunogenicity and unstable...
Approved
Investigational
Matched Description: … Emicizumab is a humanized recombinant monoclonal antibody that mimics the function of the coagulation …
Valoctocogene roxaparvovec
Valoctocogene roxaparvovec is an adeno-associated virus serotype 5 (AAV5) based gene therapy vector that expresses the B-domain deleted SQ form of human coagulation factor VIII (hFVIII-SQ). The expression of hFVIII-SQ is driven by a liver-specific promoter, which enables hepatocytes to produce factor VIII protein and increase the levels of active...
Approved
Investigational
Matched Description: … [L43282] The expression of hFVIII-SQ is driven by a liver-specific promoter, which enables hepatocytes ... [L43292] Hemophilia A treatments such as prophylactic regimens of exogenous factor VIII or [emicizumab ... roxaparvovec was approved by EMA in September 2022 and is indicated for the treatment of severe hemophilia A. …
Polidocanol
Polidocanol is a sclerosing agent indicated to treat uncomplicated spider veins (varicose veins ≤1 mm in diameter) and uncomplicated reticular veins (varicose veins 1 to 3 mm in diameter) in the lower extremity. It is marketed under the brand names Asclera and Varithena. The formula for Polidocanol has the structural...
Approved
Matched Description: … (n) of approximately 9 and a mean molecular weight of approximately 600. ... Polidocanol is a sclerosing agent indicated to treat uncomplicated spider veins (varicose veins ≤1 mm ... The formula for Polidocanol has the structural formula C12H25(OCH2CH2)nOH, a mean extent of polymerization …
Matched Categories: … Compounds used in a research, industrial, or household setting …
Matched Categories: … Compounds used in a research, industrial, or household setting …
Flutemetamol (18F)
Flutemetamol (18F) is a PET scanning radiopharmaceutical containing the radionuclide fluorine-18. It is indicated for Positron Emission Tomography (PET) imaging of the brain to estimate β amyloid neuritic plaque density in adult patients with cognitive impairment who are being evaluated for Alzheimer's disease (AD) or other causes of cognitive decline.
Approved
Investigational
Matched Description: … Flutemetamol (18F) is a PET scanning radiopharmaceutical containing the radionuclide fluorine-18. …
Matched Categories: … Compounds used in a research, industrial, or household setting …
Matched Categories: … Compounds used in a research, industrial, or household setting …
Ioxaglic acid
Ioxaglic acid is marketed as Hexabrix. This drug is an ionic tri-iodinated benzoate used as a low-osmolality contrast agent during diagnostic imaging procedures. Like other organic iodine compounds, ioxaglic acid blocks x-rays and is opaque in its appearance on x-ray film, improving the visualization of important structures and organs during...
Approved
Investigational
Matched Description: … This drug is an ionic tri-iodinated benzoate used as a low-osmolality contrast agent during diagnostic ... Ioxaglic acid has a low osmolarity and is associated with fewer side effects compared to older contrast …
Matched Categories: … Compounds used in a research, industrial, or household setting …
Matched Categories: … Compounds used in a research, industrial, or household setting …
Amaranthus palmeri pollen
Amaranthus palmeri pollen is the pollen of the Amaranthus palmeri plant. Amaranthus palmeri pollen is mainly used in allergenic testing.
Approved
Meticillin
One of the penicillins which is resistant to penicillinase but susceptible to a penicillin-binding protein. It is inactivated by gastric acid so administered by injection.
Approved
Investigational
Matched Description: … One of the penicillins which is resistant to penicillinase but susceptible to a penicillin-binding protein …
Zinc sulfate, unspecified form
Zinc sulfate is a common zinc supplement in parenteral nutrition.[A216916,L12888]
Approved
Experimental
Matched Description: … Zinc sulfate is a common zinc supplement in parenteral nutrition.[A216916,L12888] …
Chlorphenesin
Approved
Experimental
Tixocortol
Tixocortol is a 21-thiol derivative of hydrocortisone classified as a class A corticosteroid. It is a synthetic steroid with topical anti-inflammatory properties without the systemic glucocorticoid and mineralocorticoid activities and toxicity.
Approved
Withdrawn
Matched Description: … Tixocortol is a 21-thiol derivative of hydrocortisone classified as a class A corticosteroid. ... It is a synthetic steroid with topical anti-inflammatory properties without the systemic glucocorticoid …
Casein
Casein allergenic extract is used in allergenic testing.
Approved
Matched Categories: … Compounds used in a research, industrial, or household setting …
Barium sulfate
Barium sulfate is an inorganic compound with the chemical formula BaSO4 .
Barium sulfate occurs in nature as the mineral barite. It is also used in various manufacturing applications and mixed into heavy concrete to serve as a radiation shield .
This drug is used as a contrast agent in...
Approved
Matched Description: … This drug is used as a contrast agent in diagnostic x-ray procedures. ... It is also used in various manufacturing applications and mixed into heavy concrete to serve as a radiation …
Matched Categories: … Compounds used in a research, industrial, or household setting …
Matched Categories: … Compounds used in a research, industrial, or household setting …
Plazomicin
Developed by Achaogen biopharmaceuticals, plazomicin is a next-generation aminoglycoside synthetically derived from DB12604. The structure of plazomicin was established via appending hydroxylaminobutyric acid to DB12604 at position 1 and 2-hydroxyethyl group at position 6' . It was designed to evade all clinically relevant aminoglycoside-modifying enzymes, which contribute to the main...
Approved
Investigational
Matched Description: … Developed by Achaogen biopharmaceuticals, plazomicin is a next-generation aminoglycoside synthetically …
Matched Categories: … Drugs that are Mainly Renally Excreted with a Narrow Therapeutic Index …
Matched Categories: … Drugs that are Mainly Renally Excreted with a Narrow Therapeutic Index …
Verticillium albo-atrum
Verticillium albo-atrum is a fungus which can provoke allergic reactions. Verticillium albo-atrum extract is used in allergenic testing.
Approved
Matched Description: … Verticillium albo-atrum is a fungus which can provoke allergic reactions. …
Pentolinium
Pentolinium is a nicotinic antagonist that has been used as a ganglionic blocking agent in hypertension.
Approved
Matched Description: … Pentolinium is a nicotinic antagonist that has been used as a ganglionic blocking agent in hypertension …
Ethylhexyl methoxycrylene
Ethylhexyl methoxycrylene is a photostabilizer that preserves the effectiveness of UV filters by interacting with both the singlet and triplet states . It returns UV filters to their ground states without absorbing sunlight . It is used as a solvent for crystalline UV filters and is easily emulsified and suitable...
Approved
Experimental
Matched Description: … Ethylhexyl methoxycrylene is a photostabilizer that preserves the effectiveness of UV filters by interacting ... It is used as a solvent for crystalline UV filters and is easily emulsified and suitable for use in various …
Susoctocog alfa
Intravenous susoctocog alfa is a recombinant, B-domain deleted, porcine sequence antihaemophilic factor VIII (FVIII) product that has recently been approved for the treatment of bleeding episodes in adults with acquired haemophilia A (AHA). AHA is a rare bleeding disorder that results in a prolonged clotting time as measured by the...
Approved
Investigational
Matched Description: … Susoctocog alfa is a glycoprotein containing a 90 kDa heavy chain and a 80 kDa light chain with the naturally-occuring ... AHA is a rare bleeding disorder that results in a prolonged clotting time as measured by the activated ... B domain replaced with a twenty-four amino acid linker. …
Ocriplasmin
Ocriplasmin is a recombinant truncated form of human plasmin with a molecular weight of 27.2 kDa produced by recombinant DNA technology in a Pichia pastoris expression system. Ocriplasmin is a protein made up of 249 amino acids and has two peptide chains. Agent for pharmacologic vitreolysis; thrombolytic agent. FDA approved...
Approved
Matched Description: … Ocriplasmin is a recombinant truncated form of human plasmin with a molecular weight of 27.2 kDa produced ... by recombinant DNA technology in a Pichia pastoris expression system. ... Ocriplasmin is a protein made up of 249 amino acids and has two peptide chains. …
Displaying drugs 476 - 500 of 11608 in total