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Displaying drugs 726 - 750 of 15358 in total
Pyrantel is a pyrimidine-derivative anthelmintic agent for the oral treatment of various parasitic worm infections including ascariasis, hookworm infections, enterobiasis (pinworm infection), trichostrongyliasis, and trichinellosis . Pyrantel was initially described in 1965 by researchers from Pfizer who sought cyclic amidines with suitable pharmacokinetic properties (specifically, duration of action) for use...
Approved
Vet approved
Matched Iupac: … 1-methyl-2-[(E)-2-(thiophen-2-yl)ethenyl]-1,4,5,6-tetrahydropyrimidine …
Matched Description: … Pyrantel is mainly available in formulations for dogs and cats as the embonate salt, containing a 34.7% ... Pyrantel is a pyrimidine-derivative anthelmintic agent for the oral treatment of various parasitic worm ... pharmacokinetic properties (specifically, duration of action) for use as an anthelmintic drug. …
Matched Mixtures name: … Heartgard Plus Chewable Tablet for Dogs - Up to 25 lbs ... Heartgard Plus Chewable Tablet for Dogs - 26 - 50 lbs ... Heartgard Plus Chewable Tablet for Dogs - 51 - 100 lbs …
Matched Products: … KONTIL 250 MG ÇIĞNEME TABLETI, 3 ADET ... PAMOATO DE PIRENTEL SUSPENSION C 250 MG/ 5 ML …
A seasonally-specific component of the influenza vaccine. The influenza vaccine, also known as the "flu shot", is a vaccine that protects against infection from the influenza viruses. Vaccines provide protection from influenza by exposing the immune system to the virus (or parts of the virus) which stimulates an immunological defence...
Approved
Matched Description: … Inactivated vaccines contain a virus particle that has been grown in media and then subsequently killed ... , or inactivated, through exposure to heat or chemicals such as formaldehyde 3. ... A seasonally-specific component of the influenza vaccine. …
Latanoprostene Bunod has been used in trials studying the treatment of Glaucoma, Ocular Hypertension, Open-Angle Glaucoma, Open Angle Glaucoma, and Intraocular Pressure. As of November 2, 2017 the FDA approved Bausch + Lomb's Vyzulta (latanoprostene bunod opthalmic solution), 0.024% for the indication of reducing intraocular pressure in patients with open-angle...
Approved
Investigational
Matched Iupac: … 4-(nitrooxy)butyl (5Z)-7-[(1R,2R,3R,5S)-3,5-dihydroxy-2-[(3R)-3-hydroxy-5-phenylpentyl]cyclopentyl]hept …
Matched Description: … In comparison, both latanoprost and latanoprostene bunod contain a latanoprost acid backbone. ... ), 0.024% for the indication of reducing intraocular pressure in patients with open-angle glaucoma or ... As of November 2, 2017 the FDA approved Bausch + Lomb's Vyzulta (latanoprostene bunod opthalmic solution …
Miglustat, commonly marketed under the trade name Zavesca, is a drug used to treat Gaucher disease. It inhibits the enzyme glucosylceramide synthase, an essential enzyme for the synthesis of most glycosphingolipids. It is only used for patients who cannot be treated with enzyme replacement therapy with imiglucerase. Miglustat is now...
Approved
Matched Iupac: … (2R,3R,4R,5S)-1-butyl-2-(hydroxymethyl)piperidine-3,4,5-triol …
Matched Description: … in patients without a high incidence of adverse effect. ... Miglustat is now the first and only approved therapy for patients with Niemann-Pick disease type C (NP-C ... It has recently been approved for treatment of progressive neurological symptoms in adult and pediatric …
American hazelnut allergenic extract is used in allergenic testing.
Approved
Matched Description: … American hazelnut allergenic extract is used in allergenic testing. …
Fig allergenic extract is used in allergenic testing.
Approved
Matched Description: … Fig allergenic extract is used in allergenic testing. …
Flunisolide (marketed as AeroBid, Nasalide, Nasarel) is a corticosteroid with anti-inflammatory actions. It is often prescribed as treatment for allergic rhinitis and its principle mechanism of action involves activation of glucocorticoid receptors.
Approved
Investigational
Matched Iupac: … (1S,2S,4R,8S,9S,11S,12S,13R,19S)-19-fluoro-11-hydroxy-8-(2-hydroxyacetyl)-6,6,9,13-tetramethyl-5,7-dioxapentacyclo …
Matched Description: … Flunisolide (marketed as AeroBid, Nasalide, Nasarel) is a corticosteroid with anti-inflammatory actions ... It is often prescribed as treatment for allergic rhinitis and its principle mechanism of action involves …
Matched Categories: … Medications that reduce magnesium levels ... Corticosteroids for Systemic Use ... Drugs for Obstructive Airway Diseases …
Aluminum hydroxide is an inorganic salt used as an antacid. It is a basic compound that acts by neutralizing hydrochloric acid in gastric secretions. Subsequent increases in pH may inhibit the action of pepsin. An increase in bicarbonate ions and prostaglandins may also confer cytoprotective effects.
Approved
Investigational
Matched Iupac: … aluminium(3+) trihydroxide …
Matched Description: … It is a basic compound that acts by neutralizing hydrochloric acid in gastric secretions. ... Subsequent increases in pH may inhibit the action of pepsin. ... An increase in bicarbonate ions and prostaglandins may also confer cytoprotective effects. …
Matched Mixtures name: … แม๊ก 2 ... NOAX 3 ... Maalox oral suspension in sachet …
Matched Categories: … Drugs for Acid Related Disorders …
Long-acting plasma-bound sulfonamide used for respiratory and urinary tract infections and also for malaria.
Approved
Withdrawn
Matched Iupac: … 4-amino-N-(3-methoxypyrazin-2-yl)benzene-1-sulfonamide …
Matched Description: … Long-acting plasma-bound sulfonamide used for respiratory and urinary tract infections and also for malaria …
Matched Categories: … Antibacterials for Systemic Use ... Antiinfectives for Systemic Use …
A seasonally-specific component of the influenza vaccine. The influenza vaccine, also known as the "flu shot", is a vaccine that protects against infection from the influenza viruses. Vaccines provide protection from influenza by exposing the immune system to the virus (or parts of the virus) which stimulates an immunological defence...
Approved
Matched Name: … Influenza A virus A/Brisbane/02/2018 IVR-190 (H1N1) antigen (propiolactone inactivated) …
Matched Description: … Inactivated vaccines contain a virus particle that has been grown in media and then subsequently killed ... , or inactivated, through exposure to heat or chemicals such as formaldehyde 3. ... A seasonally-specific component of the influenza vaccine. …
Trichloroethylene is a halocarbon commonly used as an industrial solvent, not to be confused with the similar 1,1,1-trichloroethane, also known as chlorothene. It has been sold under a variety of trade names including Trimar and Trilene and used as a volatile anesthetic and as an inhaled obstetrical analgesic. Environmental exposure,...
Approved
Matched Synonyms: … 1,1-dichloro-2-chloroethylene …
Matched Description: … major concern for human health and has been the subject of numerous incidents and lawsuits. ... It has been sold under a variety of trade names including Trimar and Trilene and used as a volatile anesthetic ... Trichloroethylene is a halocarbon commonly used as an industrial solvent, not to be confused with the …
Matched Categories: … Compounds used in a research, industrial, or household setting …
Hyaluronic acid (HA) is an anionic, nonsulfated glycosaminoglycan found in connective, epithelial, and neural tissues; it was first isolated in 1934. Karl Meyer and John Palmer obtained glycosaminoglycan (GAG) from the bovine eye, giving it the name “hyaluronic acid”. HA is involved in many important physiological processes, including but not...
Approved
Vet approved
Matched Iupac: … (2S,3S,4R,5R,6R)-3-{[(2S,3R,5S,6R)-4-{[(2R,3R,4S,5S,6S)-6-carboxy-3,4,5-trihydroxyoxan-2-yl]oxy}-3-acetamido ... -5-hydroxy-6-(hydroxymethyl)oxan-2-yl]oxy}-6-{[(2R,3R,5S,6R)-3-acetamido-2,5-dihydroxy-6-(hydroxymethyl ... )oxan-4-yl]oxy}-4,5-dihydroxyoxane-2-carboxylic acid …
Matched Description: … A popular use of hyaluronic acid in recent years is cosmetic injection due to its ability to minimize ... [A230128] HA is used in drug delivery systems for the treatment of cancer, ophthalmological conditions ... neural tissues; it was first isolated in 1934. …
Matched Mixtures name: … Calcipotriene 0.005% / Diclofenac Sodium 3% / Hyaluronic Acid Sodium Salt 2% / Niacinamide 2% ... Le-Blen Vitamin C Serum ... Kaewoon for Men …
Matched Categories: … Compounds used in a research, industrial, or household setting ... Preparations for Treatment of Wounds and Ulcers …
Matched Products: … E- Repair ... SYNOLIS V-A ... C-eye Day …
Sparsentan is a dual antagonist of the endothelin type A receptor (ETAR) and the angiotensin II (Ang II) type 1 receptor (AT1R) with a similar affinity for both (9.3 nM for ETAR and 0.8 nM for AT1R).[A257330,L45300] Sparsentan is first in its class and orally active, and was created by...
Approved
Investigational
Matched Iupac: … 4'-({2-butyl-4-oxo-1,3-diazaspiro[4.4]non-1-en-3-yl}methyl)-N-(4,5-dimethyl-1,2-oxazol-3-yl)-2'-(ethoxymethyl ... )-[1,1'-biphenyl]-2-sulfonamide …
Matched Description: … II (Ang II) type 1 receptor (AT1R) with a similar affinity for both (9.3 nM for ETA< ... Furthermore, it is the first non-immunosuppressive therapy for the reduction of proteinuria in IgAN. ... /sub>R and 0.8 nM for AT1R). …
Matched Categories: … Angiotensin 2 Receptor Blocker ... Dual Endothelin Type A Receptor/Ang II Subtype 1 Receptor Antagonist (DEARA) …
Boldo leaf extract allergenic extract is used in allergenic testing.
Approved
Experimental
Matched Description: … Boldo leaf extract allergenic extract is used in allergenic testing. …
Drotrecogin alfa is activated human protein C that is synthesized by recombinant DNA technology. It is a glycoprotein of approximately 55 kilodalton molecular weight, consisting of a heavy chain and a light chain linked by a disulfide bond. Drotrecogin alfa was withdrawn from the market after a major study indicated...
Approved
Investigational
Withdrawn
Matched Synonyms: … Activated protein C ... Recombinant human activated protein C (rH-APC) …
Matched Description: … in improving outcomes in patients with sepsis. ... Drotrecogin alfa is activated human protein C that is synthesized by recombinant DNA technology. ... a light chain linked by a disulfide bond. …
Matched Categories: … Recombinant Activated Protein C
Pegunigalsidase alfa (PRX-102) is a recombinant form of human α-galactosidase-A indicated for long-term enzyme replacement therapy in patients with Fabry disease, a rare genetic disorder characterized by the deficiency of alpha-galactosidase A.[A259352,L46342] Unlike other forms of recombinant alpha-galactosidase A, such as agalsidase alfa and agalsidase beta, pegunigalsidase alfa uses a...
Approved
Investigational
Matched Description: … Pegunigalsidase alfa (PRX-102) is a recombinant form of human α-galactosidase-A indicated for long-term ... enzyme replacement therapy in patients with Fabry disease, a rare genetic disorder characterized by ... [A259347,A259352] In May 2023, the EMA granted marketing authorization to pegunigalsidase alfa in
Thrombotic thrombocytopenic purpura (TTP) is a rare blood clotting disorder characterized by thrombocytopenia, microangiopathic hemolytic anemia, and various degrees of organ damage. It may be inherited (congenital TTP; cTTP) or acquired due to autoantibodies (immune-mediated TTP; iTTP), although cTTP accounts for &lt;5% of all cases of TTP. Patients with cTTP...
Approved
Investigational
Matched Description: … <5% of all cases of TTP. ... ADAMTS13 plasma levels. ... November 2023 for use as an enzyme replacement therapy in patients with cTTP. …
Black sea bass allergenic extract is used in allergenic testing.
Approved
Matched Description: … Black sea bass allergenic extract is used in allergenic testing. …
Approved
Experimental
Matched Mixtures name: … C. Vit-min Formula ... Extra Once A Day ... Maximum Once A Day …
Plasminogen is a pro-enzyme (i.e. a zymogen) which is cleaved to form plasmin - also known as fibrinolysin - as part of the fibrinolytic pathway that breaks down fibrin blood clots. This pathway is activated when a clot is no longer needed or to prevent a clot from extending beyond...
Approved
Matched Description: … [L34635] In June 2021, the FDA approved a plasma-derived plasminogen (Ryplazim, human plasminogen-tvmh ... Plasminogen is a pro-enzyme (i.e. a zymogen) which is cleaved to form plasmin - also known as [fibrinolysin ... )[L34620] for the treatment of type 1 plasminogen deficiency (hypoplasminogenemia). …
Defibrotide is the sodium salt of a mixture of single-stranded oligodeoxyribonucleotides derived from porcine mucosal DNA. It has been shown to have antithrombotic, anti-inflammatory and anti-ischemic properties (but without associated significant systemic anticoagulant effects). It is marketed under the brand names Dasovas (FM), Noravid, and Prociclide in a variety of...
Approved
Investigational
Matched Description: … It is marketed under the brand names Dasovas (FM), Noravid, and Prociclide in a variety of countries. ... In the USA it is was approved in March, 2016 as Defitelio. ... Defibrotide is the sodium salt of a mixture of single-stranded oligodeoxyribonucleotides derived from …
Simethicone is a silicon based surfactant that decreases the surface tension of gastrointestinal gas bubbles to facilitate their elimination. It has a favourable safety profile as it is not systemically absorbed. Simethicone has been in use since the 1940s but was granted FDA approval in 1952.
Approved
Matched Description: … [A228308] Simethicone has been in use since the 1940s[A228303] but was granted FDA approval in 1952 ... [A228308] It has a favourable safety profile as it is not systemically absorbed. ... Simethicone is a silicon based surfactant that decreases the surface tension of gastrointestinal gas …
Matched Mixtures name: … NOAX 3 ... GASTROPAX F ... E-Z-GAS II GRANULES …
Matched Categories: … Compounds used in a research, industrial, or household setting …
Matched Products: … Ovol for Gas 80 Mg Tablet ... Ovol for Gas 180 Mg Tablet ... Ovol for Gas 180 Mg Capsule …
Egg allergenic extract is used in allergenic testing.
Approved
Matched Description: … Egg allergenic extract is used in allergenic testing. …
A seasonally-specific component of the influenza vaccine. The influenza vaccine, also known as the "flu shot", is a vaccine that protects against infection from the influenza viruses. Vaccines provide protection from influenza by exposing the immune system to the virus (or parts of the virus) which stimulates an immunological defence...
Approved
Matched Description: … Inactivated vaccines contain a virus particle that has been grown in media and then subsequently killed ... , or inactivated, through exposure to heat or chemicals such as formaldehyde 3. ... A seasonally-specific component of the influenza vaccine. …
Displaying drugs 726 - 750 of 15358 in total