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Displaying drugs 851 - 875 of 11797 in total

Iobenguane

Synthetic guanethidine derivative that locates phaeochromocytomas and neuroblastomas. The radioisotope used can either be iodine-123 for imaging or iodine-131 for destruction of tissues that metabolize noradrenaline. Iodine 123 is a cyclotron-produced radionuclide that decays to Te 123 by electron capture. Images are produced by a I123 MIBG scintigraphy. FDA approved...
Approved
Investigational
Matched Description: … Images are produced by a I123 MIBG scintigraphy. FDA approved on September 19, 2008. ... Iodine 123 is a cyclotron-produced radionuclide that decays to Te 123 by electron capture. …
Matched Categories: … Compounds used in a research, industrial, or household setting …

Ergosterol

A steroid of interest both because its biosynthesis in FUNGI is a target of ANTIFUNGAL AGENTS, notably AZOLES, and because when it is present in SKIN of animals, ULTRAVIOLET RAYS break a bond to result in ERGOCALCIFEROL.
Approved
Experimental
Matched Iupac: … 5,6-dimethylhept-3-en-2-yl]-9a,11a-dimethyl-1H,2H,3H,3aH,6H,7H,8H,9H,9aH,9bH,10H,11H,11aH-cyclopenta[a] …
Matched Description: … A steroid of interest both because its biosynthesis in FUNGI is a target of ANTIFUNGAL AGENTS, notably ... AZOLES, and because when it is present in SKIN of animals, ULTRAVIOLET RAYS break a bond to result in …

Poa annua pollen

Poa annua pollen is the pollen of the Poa annua plant. Poa annua pollen is mainly used in allergenic testing.
Approved

Factor XIII (human)

Factor XIII (human) is a heat-treated, lyophilized concentrate of coagulation factor XIII, an endogenous enzyme responsible for the crosslinking of fibrin and an essential component of the coagulation cascade [FDA Label]. For people with congenital deficiency or mutation of Factor XIII, a rare bleeding disorder, exogenous replacement of this key...
Approved
Investigational
Matched Description: … Within the body, FXIII circulates as a heterotetramer composed of 2 A-subunits and 2 B-subunits (A2B2 ... As a result, the active transglutaminase from subunit A cross-links fibrin and other proteins resulting ... recombinant form of the A subunit of human coagulation factor XIII. …

Casein

Casein allergenic extract is used in allergenic testing.
Approved
Matched Categories: … Compounds used in a research, industrial, or household setting …

Mephenesin

Mephenesin is a synthetic cresol glyceryl ether which produces transient muscle relaxation and paralysis via central nervous system depression . It first entered use in the 1950s.
Approved
Matched Description: … Mephenesin is a synthetic cresol glyceryl ether which produces transient muscle relaxation and paralysis …

Ferric maltol

Ferric maltol is an iron(III) atom complexed with 3 maltol molecules to increase the bioavailability compared to iron(II), without depositing it in the duodenum as insoluble ferric hydroxide and phosphate. Ferric maltol has been described in literature since at least the late 1980s as a potential treatment for iron deficiency....
Approved
Matched Description: … [A189288] Ferric maltol has been described in literature since at least the late 1980s as a potential …

Amaranthus hybridus pollen

Amaranthus hybridus pollen allergenic extract is used in allergenic testing.
Approved

Danaparoid

Danaparoid is a low-molecular-weight heparinoid with an average molecular weight of 5500 Daltons consisting of a mixture of glycosaminoglycans . The active constituents are heparan, dermatan and DB09301 , and they are isolated from the porcine intestinal mucosa [FDA Label]. Danaparoid possesses a potent antithrombic activity that works by inhibiting...
Approved
Withdrawn
Matched Description: … of a mixture of glycosaminoglycans [A32565]. ... Danaparoid is a low-molecular-weight heparinoid with an average molecular weight of 5500 Daltons consisting ... Danaparoid possesses a potent antithrombic activity that works by inhibiting activated factor X (Factor …

Undecoylium chloride iodine complex

Approved

Nitroprusside

Nitroprusside serves as a source of nitric oxide, a potent peripheral vasodilator that affects both arterioles and venules (venules more than arterioles). Nitroprusside is often administered intravenously to patients who are experiencing a hypertensive emergency.
Approved
Investigational
Matched Description: … Nitroprusside serves as a source of nitric oxide, a potent peripheral vasodilator that affects both arterioles ... Nitroprusside is often administered intravenously to patients who are experiencing a hypertensive emergency …
Matched Categories: … Compounds used in a research, industrial, or household setting …

Tetradecyl hydrogen sulfate (ester)

Sodium tetradecyl sulfate is an anionic surface-active agent which is used for its wetting properties in the industry and is also used in medicine as a blood vessel irritant and sclerosing agent for hemorrhoids and varicose veins . Sodium tetradecyl sulfate has been widely used since the 1950s, and in...
Approved
Matched Description: … 30% incidence of post-sclerosis pigmentation that resolved within a few months [L2035]. ... sulfate has been widely used since the 1950s, and in 1978 the first successful report of injecting a ... surface-active agent which is used for its wetting properties in the industry and is also used in medicine as a …

Beroctocog alfa

Approved
Investigational

Padimate O

Padimate O is an active sunscreen agent in cosmetics and over-the-counter sunscreen drug products in concentrations up to 8%, as regulated by the FDA . It is a structurally-related compound to DB02362 that absorbs UV-B rays to prevent photodamage. It penetrates human skin, and is shown to induce non-ligatable strand...
Approved
Matched Description: … It is a structurally-related compound to [DB02362] that absorbs UV-B rays to prevent photodamage. …
Matched Categories: … Compounds used in a research, industrial, or household setting …

Flavone

Approved
Experimental

Cedazuridine

Myelodysplastic syndromes (MDS) are a group of hematopoietic neoplasms that give rise to variable cytopenias progressing to secondary acute myeloid leukemia (sAML), which is invariably fatal if untreated.[A215082, A215092, A215097] Hypomethylating agents such as decitabine and azacitidine are used to treat MDS through inducing DNA hypomethylation and apoptosis of cancerous...
Approved
Investigational
Matched Description: … Myelodysplastic syndromes (MDS) are a group of hematopoietic neoplasms that give rise to variable cytopenias ... [A215107, A215112, A215117, A215127] Cedazuridine is a fluorinated tetrahydrouridine derivative specifically …

Thonzonium

Thonzonium is a monocationic surface-active agent with surfactant and detergent properties. It is widely used as an additive to in ear and nasal drops to enhance dispersion and penetration of cellular debris and exudate, thereby promoting tissue contact of the administered medication. A common pharmaceutical formulation of thonzonium bromide is...
Approved
Matched Description: … Thonzonium is a monocationic surface-active agent with surfactant and detergent properties. ... A common pharmaceutical formulation of thonzonium bromide is cortisporin-TC ear drops. …

Famciclovir

Famciclovir, marketed as Famvir by Novartis, is a guanine analogue used to treat herpes virus infections. It is most commonly used to treat herpes zoster (shingles). Famciclovir is a prodrug of penciclovir with higher oral bioavailability.
Approved
Investigational
Matched Description: … Famciclovir is a prodrug of penciclovir with higher oral bioavailability. ... Famciclovir, marketed as Famvir by Novartis, is a guanine analogue used to treat herpes virus infections …

Rimegepant

Rimegepant is an oral antagonist of the CGRP receptor developed by Biohaven Pharmaceuticals. It received FDA approval on February 27, 2020 for the acute treatment migraine headache, and was subsequently approved by the European Commission in April 2022 for both the treatment and prevention of migraines. While several parenteral antagonists...
Approved
Investigational

Iohexol

Iohexol is an effective non-ionic, water-soluble contrast agent which is used in myelography, arthrography, nephroangiography, arteriography, and other radiographic procedures. Its low systemic toxicity is the combined result of low chemotoxicity and low osmolality.
Approved
Matched Categories: … Compounds used in a research, industrial, or household setting …

Verapamil

Verapamil is a phenylalkylamine calcium channel blocker used in the treatment of high blood pressure, heart arrhythmias, and angina, and was the first calcium channel antagonist to be introduced into therapy in the early 1960s. It is a member of the non-dihydropyridine class of calcium channel blockers, which includes drugs...
Approved
Matched Description: … Verapamil is a phenylalkylamine calcium channel blocker used in the treatment of high blood pressure, ... [A188514] It is a member of the non-dihydropyridine class of calcium channel blockers, which includes ... [L8791] Verapamil is administered as a racemic mixture containing equal amounts of the S- and R-enantiomer …

Osilodrostat

Osilodrostat is an inhibitor of 11β-hydroxylase (also referred to as CYP11B1), the enzyme that catalyzes the final step in the biosynthesis of endogenous cortisol. It is used to lower circulating cortisol levels in the treatment of Cushing's disease, a disorder in which cortisol levels are chronically and supraphysiologically elevated. Cushing's...
Approved
Investigational
Matched Description: … [A191910] As an orally bioavailable drug therapy, osilodrostat provides a novel treatment option for ... [L12123] It is used to lower circulating cortisol levels in the treatment of Cushing's disease, a disorder ... Cushing's disease is often the result of ACTH hypersecretion secondary to a pituitary tumor, and surgical …

Magnesium cation

Magnesium hydroxide is used primarily in "Milk of Magnesia", a white aqueous, mildly alkaline suspension of magnesium hydroxide formulated at about 8%w/v. Milk of magnesia is primarily used to alleviate constipation, but can also be used to relieve indigestion and heartburn. When taken internally by mouth as a laxative, the...
Approved
Nutraceutical
Matched Description: … Magnesium hydroxide is used primarily in "Milk of Magnesia", a white aqueous, mildly alkaline suspension ... When taken internally by mouth as a laxative, the osmotic force of the magnesia suspension acts to draw …

Delandistrogene moxeparvovec

Delandistrogene moxeparvovec is an adeno-associated virus vector-based gene therapy developed by Sarepta Therapeutics. It was granted accelerated approval by the FDA on June 22, 2023, as the first gene therapy to treat Duchenne Muscular Dystrophy (DMD). DMD is an X-linked genetic disorder characterized by mutations in the dystrophin gene, leading...
Approved
Investigational
Matched Description: … Microdystrophin is a truncated, functional form of dystrophin.[A260256, L47021] ... ] DMD is an X-linked genetic disorder characterized by mutations in the dystrophin gene, leading to a ... serotype rh74 (AAVrh74) based vector containing the microdystrophin transgene under the control of a …

Wormwood

Wormwood is a plant/plant extract used in some OTC (over-the-counter) products. It is not an approved drug.
Approved
Experimental
Matched Description: … Wormwood is a plant/plant extract used in some OTC (over-the-counter) products. …
Displaying drugs 851 - 875 of 11797 in total