Displaying drugs 1051 - 1075 of 15551 in total
Crisaborole
Crisaborole is a novel oxaborole approved by FDA on December 14, 2016 as Eucrisa, a topical treatment of for mild to moderate atopic dermatitis.
This non-steroidal agent is efficacious in improving disease severity, reducing the risk of infection and reducing the signs and symptoms in patients 2 years old and...
Approved
Investigational
Matched Description: … and reducing the signs and symptoms in patients 2 years old and older. ... of for mild to moderate atopic dermatitis. ... It reduces the local inflammation in the skin and prevents further exacerbation of the disease with a …
Matched Categories: … Agents for Dermatitis, Excluding Corticosteroids …
Matched Products: … Staquis Topical Ointment 2% …
Matched Categories: … Agents for Dermatitis, Excluding Corticosteroids …
Matched Products: … Staquis Topical Ointment 2% …
Sus scrofa skin
Sus scrofa skin or pelt is used in allergenic testing.
Approved
Matched Description: … Sus scrofa skin or pelt is used in allergenic testing. …
Peginterferon beta-1a
Multiple Sclerosis (MS) is a chronic and inflammatory autoimmune disease of the central nervous system, disrupting communication between the brain and other parts of the body. Most patients diagnosed with this illness experience their initial disease symptoms between the age of 20 to 40, often the most productive years of...
Approved
Matched Description: … It was originally approved by the FDA in 2014 for subcutaneous use, and was approved for intramuscular ... Multiple Sclerosis (MS) is a chronic and inflammatory autoimmune disease of the central nervous system ... occur more frequently in women than in men. …
Matched Categories: … Compounds used in a research, industrial, or household setting …
Matched Products: … PLEGRİDY 125 MCG/0.5 ML SC ENJEKSİYONLUK ÇÖZELTİ İÇEREN KULLANIMA HAZIR KALEM, 2 ADET …
Matched Categories: … Compounds used in a research, industrial, or household setting …
Matched Products: … PLEGRİDY 125 MCG/0.5 ML SC ENJEKSİYONLUK ÇÖZELTİ İÇEREN KULLANIMA HAZIR KALEM, 2 ADET …
Sodium tartrate
Sodium tartrate is a disodium salt of l-( + )-tartaric acid that is identified by transparent, colorless, and odorless crystals. It is obtained as a byproduct of wine manufacturing. Sodium tartrate is generally recognized as safe (GRAS) as a direct human food ingredient. It acts as an emulsifier and pH...
Approved
Matched Description: … It acts as an emulsifier and pH control agent in food products [L2590]. ... It is obtained as a byproduct of wine manufacturing. ... This compound is commonly used as an emulsifier in cheese/cheese spread products and is not to exceed …
Matched Categories: … Drugs for Constipation …
Matched Categories: … Drugs for Constipation …
Colchicine
Colchicine is an alkaloid drug derived from a plant belonging to the Lily family, known as Colchicum autumnale, or "autumn crocus." Its use was first approved by the FDA in 1961. Colchicine is used in the treatment of gout flares and Familial Mediterranean fever, and prevention of major cardiovascular events....
Approved
Matched Iupac: … N-[(10S)-3,4,5,14-tetramethoxy-13-oxotricyclo[9.5.0.0^{2,7}]hexadeca-1(16),2(7),3,5,11,14-hexaen-10-yl …
Matched Description: … Colchicine is an alkaloid drug derived from a plant belonging to the Lily family, known as _Colchicum ... [A183611] Its use was first approved by the FDA in 1961. ... [L47591] It has also been investigated in other inflammatory and fibrotic conditions.[A183602] …
Matched Categories: … Experimental Unapproved Treatments for COVID-19 …
Matched Description: … Colchicine is an alkaloid drug derived from a plant belonging to the Lily family, known as _Colchicum ... [A183611] Its use was first approved by the FDA in 1961. ... [L47591] It has also been investigated in other inflammatory and fibrotic conditions.[A183602] …
Matched Categories: … Experimental Unapproved Treatments for COVID-19 …
Pizotifen
Pizotifen belongs to the class of antamines and is related to cyproheptadine. It is a potent serotonin and tryptamine antagonist that has been used for migraine prevention for many years. It exhibits weak anticholinergic, antihistamine, and antikinin actions in addition to sedative and appetite-stimulating properties . Some patients receiving pizotifen...
Approved
Matched Iupac: … 1-methyl-4-{6-thiatricyclo[8.4.0.0³,⁷]tetradeca-1(14),3(7),4,10,12-pentaen-2-ylidene}piperidine …
Matched Description: … Sandomigran is available in a number of countries but is not approved by the FDA nor EMA. ... [A32532] It is a potent serotonin and tryptamine antagonist that has been used for migraine prevention ... Pizotifen hydrochloride is an active ingredient in Sandomigran, which is used for the prophylactic management …
Matched Description: … Sandomigran is available in a number of countries but is not approved by the FDA nor EMA. ... [A32532] It is a potent serotonin and tryptamine antagonist that has been used for migraine prevention ... Pizotifen hydrochloride is an active ingredient in Sandomigran, which is used for the prophylactic management …
White mustard seed
White mustard seed allergenic extract is used in allergenic testing.
Approved
Matched Description: … White mustard seed allergenic extract is used in allergenic testing. …
Papaverine
An alkaloid found in opium but not closely related to the other opium alkaloids in its structure or pharmacological actions. It is a direct-acting smooth muscle relaxant used in the treatment of impotence and as a vasodilator, especially for cerebral vasodilation. The mechanism of its pharmacological actions is not clear,...
Approved
Investigational
Matched Description: … It is a direct-acting smooth muscle relaxant used in the treatment of impotence and as a vasodilator, ... especially for cerebral vasodilation. ... An alkaloid found in opium but not closely related to the other opium alkaloids in its structure or pharmacological …
Matched Categories: … Heterocyclic Compounds, 2-Ring ... Drugs Used in Erectile Dysfunction ... Drugs for Functional Gastrointestinal Disorders …
Matched Products: … PAPAVERIN HIDROKLORUR 0.04 G/2 ML BIOSEL AMPUL, 10 ADET ... PAPAVERIN HIDROKLORUR 0.05 G/2 ML BIOSEL AMPUL, 10 ADET ... PAPAVERIN HIDROKLORUR 0.06 G/2 ML BIOSEL AMPUL, 10 ADET …
Matched Categories: … Heterocyclic Compounds, 2-Ring ... Drugs Used in Erectile Dysfunction ... Drugs for Functional Gastrointestinal Disorders …
Matched Products: … PAPAVERIN HIDROKLORUR 0.04 G/2 ML BIOSEL AMPUL, 10 ADET ... PAPAVERIN HIDROKLORUR 0.05 G/2 ML BIOSEL AMPUL, 10 ADET ... PAPAVERIN HIDROKLORUR 0.06 G/2 ML BIOSEL AMPUL, 10 ADET …
Technetium Tc-99m exametazime
Technetium Tc-99m exametazime is a radiopharmaceutical sold under the trade name Ceretec used in the detection of altered regional cerebral perfusion in stroke and other cerebrovascular diseases. It can also be used for the labelling of leukocytes to localise intra-abdominal infections and inflammatory bowel disease. Exametazime, also known as hexamethylpropyleneamine...
Approved
Matched Description: … Technetium Tc-99m exametazime is a radiopharmaceutical sold under the trade name Ceretec used in the ... Exametazime, also known as hexamethylpropyleneamine oxime or HMPAO, acts as a chelating agent for the ... detection of altered regional cerebral perfusion in stroke and other cerebrovascular diseases. …
Matched Categories: … Compounds used in a research, industrial, or household setting …
Matched Categories: … Compounds used in a research, industrial, or household setting …
Pimethixene
Pimethixene is approved for use in Brazil and is marketed under the trade name Muricalm. It is an anticholinergic used in the treatment of bronchitis.
Approved
Matched Description: … Pimethixene is approved for use in Brazil and is marketed under the trade name Muricalm. ... It is an anticholinergic used in the treatment of bronchitis. …
Matched Categories: … Antihistamines for Systemic Use ... Heterocyclic Compounds, 3-Ring …
Matched Categories: … Antihistamines for Systemic Use ... Heterocyclic Compounds, 3-Ring …
Alogliptin
Alogliptin is a selective, orally-bioavailable inhibitor of enzymatic activity of dipeptidyl peptidase-4 (DPP-4). Chemically, alogliptin is prepared as a benzoate salt and exists predominantly as the R-enantiomer (>99%). It undergoes little or no chiral conversion in vivo to the (S)-enantiomer. FDA approved January 25, 2013.
Approved
Matched Iupac: … 2-({6-[(3R)-3-aminopiperidin-1-yl]-3-methyl-2,4-dioxo-1,2,3,4-tetrahydropyrimidin-1-yl}methyl)benzonitrile …
Matched Description: … It undergoes little or no chiral conversion in vivo to the (S)-enantiomer. ... Alogliptin is a selective, orally-bioavailable inhibitor of enzymatic activity of dipeptidyl peptidase ... Chemically, alogliptin is prepared as a benzoate salt and exists predominantly as the R-enantiomer (> …
Matched Categories: … Drugs Used in Diabetes …
Matched Description: … It undergoes little or no chiral conversion in vivo to the (S)-enantiomer. ... Alogliptin is a selective, orally-bioavailable inhibitor of enzymatic activity of dipeptidyl peptidase ... Chemically, alogliptin is prepared as a benzoate salt and exists predominantly as the R-enantiomer (> …
Matched Categories: … Drugs Used in Diabetes …
Ubrogepant
Ubrogepant is indicated for the acute treatment of migraine headaches with or without aura in adults. It was approved by the FDA on December 23, 2019, and is the first oral calcitonin gene-related peptide (CGRP) receptor antagonist approved for the acute treatment of migraine. Several oral small molecule CGRP receptor...
Approved
Investigational
Matched Iupac: … (6S)-N-[(3S,5S,6R)-6-methyl-2-oxo-5-phenyl-1-(2,2,2-trifluoroethyl)piperidin-3-yl]-2'-oxo-1',2',5,7-tetrahydrospiro ... [cyclopenta[b]pyridine-6,3'-pyrrolo[2,3-b]pyridine]-3-carboxamide …
Matched Description: … Ubrogepant is indicated for the acute treatment of migraine headaches with or without aura in adults. ... to as "gepants", have been investigated for migraines, but only ubrogepant and [rimegepant] remain in ... advance in migraine headache treatment and may become the new standard of therapy in the treatment of …
Matched Categories: … Monoamine Oxidase A Inhibitors for interaction with Monoamine Oxidase A substrates …
Matched Description: … Ubrogepant is indicated for the acute treatment of migraine headaches with or without aura in adults. ... to as "gepants", have been investigated for migraines, but only ubrogepant and [rimegepant] remain in ... advance in migraine headache treatment and may become the new standard of therapy in the treatment of …
Matched Categories: … Monoamine Oxidase A Inhibitors for interaction with Monoamine Oxidase A substrates …
Vardenafil
Vardenafil is a selective inhibitor of cyclic guanosine monophosphate (cGMP)-specific phosphodiesterase type 5 (PDE5) and an oral therapy for the treatment of erectile dysfunction.[L45563,L45568] During sexual stimulation, nitric oxide (NO) is released from nerve endings and endothelial cells in the corpus cavernosum, activating the enzyme guanylate cyclase and increasing the...
Approved
Matched Iupac: … 2-{2-ethoxy-5-[(4-ethylpiperazin-1-yl)sulfonyl]phenyl}-5-methyl-7-propyl-1H,4H-imidazo[4,3-f][1,2,4]triazin …
Matched Description: … [A258313] The use of vardenafil as a monotherapy for the treatment of pulmonary arterial hypertension ... [A258318] The FDA approved the use of vardenafil for the treatment of erectile dysfunction in 2003 ... selectivity for other PDE isoforms is lower than the one detected for tadalafil. …
Matched Salts cas: … 330808-88-3 …
Matched Categories: … Drugs Used in Erectile Dysfunction …
Matched Products: … Vardenafil 1 A Pharma 5 mg - Filmtabletten ... Vardenafil 1 A Pharma 10 mg - Filmtabletten ... Vardenafil 1 A Pharma 20 mg - Filmtabletten …
Matched Description: … [A258313] The use of vardenafil as a monotherapy for the treatment of pulmonary arterial hypertension ... [A258318] The FDA approved the use of vardenafil for the treatment of erectile dysfunction in 2003 ... selectivity for other PDE isoforms is lower than the one detected for tadalafil. …
Matched Salts cas: … 330808-88-3 …
Matched Categories: … Drugs Used in Erectile Dysfunction …
Matched Products: … Vardenafil 1 A Pharma 5 mg - Filmtabletten ... Vardenafil 1 A Pharma 10 mg - Filmtabletten ... Vardenafil 1 A Pharma 20 mg - Filmtabletten …
Sulfameter
Long acting sulfonamide used in leprosy, urinary, and respiratory tract infections.
Approved
Matched Iupac: … 4-amino-N-(5-methoxypyrimidin-2-yl)benzene-1-sulfonamide …
Matched Description: … Long acting sulfonamide used in leprosy, urinary, and respiratory tract infections. …
Matched Categories: … Antibacterials for Systemic Use ... Antiinfectives for Systemic Use …
Matched Description: … Long acting sulfonamide used in leprosy, urinary, and respiratory tract infections. …
Matched Categories: … Antibacterials for Systemic Use ... Antiinfectives for Systemic Use …
Pentastarch
Pentastarch is an artificial colloid (hydroxyethyl starch derivative). Pentastarch is characterized by presenting five hydroxyethyl groups, which signifies an approximate 50% hydroxyethylation. It is sold under the name Pentaspan by Bristol-Myers Squibb and is used for fluid resuscitation. When administered, pentastarch remains mainly in the circulatory system and hence, it...
Approved
Investigational
Matched Description: … When administered, pentastarch remains mainly in the circulatory system and hence, it is considered a ... It is sold under the name Pentaspan by Bristol-Myers Squibb and is used for fluid resuscitation. …
Matched Categories: … Compounds used in a research, industrial, or household setting …
Matched Categories: … Compounds used in a research, industrial, or household setting …
Aureobasidium pullulans var. pullutans
Aureobasidium pullulans var. pullutans is a fungus which can provoke allergic reactions. Aureobasidium pullulans var. pullutans extract is used in allergenic testing.
Approved
Matched Description: … Aureobasidium pullulans var. pullutans extract is used in allergenic testing. ... Aureobasidium pullulans var. pullutans is a fungus which can provoke allergic reactions. …
Matched Mixtures name: … A Mold Mixture ... A Mold Mixture ... A Mold Mixture …
Matched Mixtures name: … A Mold Mixture ... A Mold Mixture ... A Mold Mixture …
Methacholine
Asthma is a complex condition associated with phenomena such as airway hyperresponsiveness (AHR), in which the smooth muscle in the airways (ASM) excessively contracts in response to stimuli, reducing pulmonary function and causing symptoms such as difficulty breathing.[A229598, A229603] Although the underlying pathology of AHR is complex, ASM contraction can...
Approved
Investigational
Matched Iupac: … [2-(acetyloxy)propyl]trimethylazanium …
Matched Description: … Asthma is a complex condition associated with phenomena such as airway hyperresponsiveness (AHR), in ... [L31763] In patients with AHR, a lower dose of methacholine is required to induce bronchoconstriction ... , which forms the basis for the methacholine challenge test to diagnose AHR. …
Matched Description: … Asthma is a complex condition associated with phenomena such as airway hyperresponsiveness (AHR), in ... [L31763] In patients with AHR, a lower dose of methacholine is required to induce bronchoconstriction ... , which forms the basis for the methacholine challenge test to diagnose AHR. …
Dicoria canescens pollen
Dicoria canescens pollen is the pollen of the Dicoria canescens plant. Dicoria canescens pollen is mainly used in allergenic testing.
Approved
Matched Description: … Dicoria canescens pollen is mainly used in allergenic testing. …
Cyclizine
A histamine H1 antagonist given by mouth or parenterally for the control of postoperative and drug-induced vomiting and in motion sickness. (From Martindale, The Extra Pharmacopoeia, 30th ed, p935)
Approved
Matched Description: … A histamine H1 antagonist given by mouth or parenterally for the control of postoperative and drug-induced ... vomiting and in motion sickness. …
Matched Salts cas: … 303-25-3 …
Matched Categories: … Antihistamines for Systemic Use …
Matched Salts cas: … 303-25-3 …
Matched Categories: … Antihistamines for Systemic Use …
Ketazolam
Ketazolam is a benzodiazepine derivative with anxiolytic, anticonvulsant, sedative and skeletal muscle relaxant activity. Ketazolam is not approved in Canada or America.
Approved
Matched Iupac: … 14-chloro-4,10-dimethyl-2-phenyl-3-oxa-7,10-diazatricyclo[9.4.0.0^{2,7}]pentadeca-1(11),4,12,14-tetraene …
Matched Description: … Ketazolam is not approved in Canada or America. ... Ketazolam is a benzodiazepine derivative with anxiolytic, anticonvulsant, sedative and skeletal muscle …
Matched Categories: … Heterocyclic Compounds, 2-Ring …
Matched Description: … Ketazolam is not approved in Canada or America. ... Ketazolam is a benzodiazepine derivative with anxiolytic, anticonvulsant, sedative and skeletal muscle …
Matched Categories: … Heterocyclic Compounds, 2-Ring …
Lopinavir
Lopinavir is an antiretroviral protease inhibitor used in combination with other antiretrovirals in the treatment of HIV-1 infection. Lopinavir is marketed and administered exclusively in combination with ritonavir - this combination, first marketed by Abbott under the brand name Kaletra in 2000, is necessary due to lopinavir's poor oral bioavailability...
Approved
Matched Iupac: … (2S)-N-[(2S,4S,5S)-5-[2-(2,6-dimethylphenoxy)acetamido]-4-hydroxy-1,6-diphenylhexan-2-yl]-3-methyl-2- ... (2-oxo-1,3-diazinan-1-yl)butanamide …
Matched Description: … Ritonavir is a potent inhibitor of the enzymes responsible for lopinavir metabolism, and its co-administration ... of COVID-19 caused by SARS-CoV-2. ... [A191757] Lopinavir was previously under investigation in combination with ritonavir for the treatment …
Matched Mixtures name: … LOPINAVIR E RITONAVIR MYLAN ... LOPINAVIR E RITONAVIR MYLAN ... LOPINAVIR E RITONAVIR MYLAN …
Matched Categories: … Antivirals used in combination for the treatment of HIV infections ... Antivirals for Systemic Use ... Antiinfectives for Systemic Use ... Experimental Unapproved Treatments for COVID-19 …
Matched Description: … Ritonavir is a potent inhibitor of the enzymes responsible for lopinavir metabolism, and its co-administration ... of COVID-19 caused by SARS-CoV-2. ... [A191757] Lopinavir was previously under investigation in combination with ritonavir for the treatment …
Matched Mixtures name: … LOPINAVIR E RITONAVIR MYLAN ... LOPINAVIR E RITONAVIR MYLAN ... LOPINAVIR E RITONAVIR MYLAN …
Matched Categories: … Antivirals used in combination for the treatment of HIV infections ... Antivirals for Systemic Use ... Antiinfectives for Systemic Use ... Experimental Unapproved Treatments for COVID-19 …
Clodronic acid
Clodronic acid is a first generation bisphosphonate similar to etidronic acid and tiludronic acid. These drugs were developed to mimic the action of pyrophosphate, a regulator of calcification and decalcification. clodronate’s use has decreased over the years in favor of the third generation, nitrogen containing bisphosphonate zoledronic acid, ibandronic acid,...
Approved
Investigational
Vet approved
Matched Description: … [A203111]
Clodronic acid is not FDA approved, but is approved in Canada.[L13910] ... Clodronic acid is a first generation bisphosphonate similar to [etidronic acid] and [tiludronic acid] ... [A203111] These drugs were developed to mimic the action of pyrophosphate, a regulator of calcification …
Matched Categories: … Drugs for Treatment of Bone Diseases …
Matched Categories: … Drugs for Treatment of Bone Diseases …
Perboric acid
Perboric acid is mainly found in its salt form of sodium perborate and it can be found as a monohydrate or tetrahydrate. It is one of the peroxy acid salts with very wide functionalities in industrial settings. Perboric acid in the form of sodium perborate is approved by Health Canada...
Approved
Matched Description: … Perboric acid is mainly found in its salt form of sodium perborate and it can be found as a monohydrate ... as a disinfectant of medical instruments. ... [L1113] By the FDA, sodium perborate is approved as an ointment for the protection of poison ivy dermatitis …
Matched Categories: … Antiinfectives and Antiseptics for Local Oral Treatment …
Matched Categories: … Antiinfectives and Antiseptics for Local Oral Treatment …
Lomifylline
Approved
Matched Categories: … Heterocyclic Compounds, 2-Ring ... Drugs for Obstructive Airway Diseases …
Padeliporfin
Padeliporfin is a water-soluble chlorophyll derivative and cytotoxic photosensitizer used for vascular-targeted photodynamic therapy for malignancies. Vascular-targeted photodynamic therapy (VTP), or vascular targeted photochemotherapy, is a focal treatment for localized prostate cancer. It aims to destroy only cancerous lesions of the prostate, rather than ablating the entire prostate gland. Padeliporfin...
Approved
Experimental
Matched Iupac: … }]tetracosa-1,3(24),6,8,10,12,16(22),17,19-nonaene-21,23-diide ... palladium(2+) (4S,5S,14R,15R)-10-acetyl-4-(2-carboxyethyl)-15-ethyl-2-(2-methoxy-2-oxoethyl)-5,9,14,19 ... -tetramethyl-20-[(2-sulfoethyl)carbamoyl]-21,22,23,24-tetraazapentacyclo[16.2.1.1^{3,6}.1^{8,11}.1^{13,16 …
Matched Description: … Padeliporfin is a water-soluble chlorophyll derivative and cytotoxic photosensitizer used for vascular-targeted ... of low-risk prostate cancer in adults meeting certain clinical criteria. ... [A244559] Vascular-targeted photodynamic therapy (VTP), or vascular targeted photochemotherapy, is a …
Matched Categories: … Sensitizers Used in Photodynamic/radiation Therapy …
Matched Description: … Padeliporfin is a water-soluble chlorophyll derivative and cytotoxic photosensitizer used for vascular-targeted ... of low-risk prostate cancer in adults meeting certain clinical criteria. ... [A244559] Vascular-targeted photodynamic therapy (VTP), or vascular targeted photochemotherapy, is a …
Matched Categories: … Sensitizers Used in Photodynamic/radiation Therapy …
Displaying drugs 1051 - 1075 of 15551 in total