Displaying drugs 1051 - 1075 of 11782 in total
Autologous peripheral blood-derived CD34+ cells
Autologous peripheral blood-derived CD34+ cells, or CLBS119 (a proprietary version being developed by Caladrius Biosciences, Inc.), are hematopoietic stem cells. It is also a cell therapy being investigated by Caladrius Biosciences in the clinical trial NCT04522817 (CLBS119 for Repair of COVID-19 Induced Pulmonary Damage).
Approved
Investigational
Matched Description: … Autologous peripheral blood-derived CD34+ cells, or CLBS119 (a proprietary version being developed by ... [L27741] It is also a cell therapy being investigated by Caladrius Biosciences in the clinical trial …
Recombinant stabilized RSV B prefusion F antigen
Recombinant stabilized RSV B prefusion F antigen is one component of a bivalent respiratory syncytial virus (RSV) vaccine called Abrysvo. The vaccine comprises two antigens - the other being recombinant stabilized RSV A prefusion F antigen - which have been expressed in Chinese hamster ovary cell lines and then purified...
Approved
Matched Description: … Recombinant stabilized RSV B prefusion F antigen is one component of a bivalent respiratory syncytial ... The vaccine comprises two antigens - the other being [recombinant stabilized RSV A prefusion F antigen …
Pentobarbital
A short-acting barbiturate that is effective as a sedative and hypnotic (but not as an anti-anxiety) agent and is usually given orally. It is prescribed more frequently for sleep induction than for sedation but, like similar agents, may lose its effectiveness by the second week of continued administration. (From AMA...
Approved
Investigational
Vet approved
Matched Description: … A short-acting barbiturate that is effective as a sedative and hypnotic (but not as an anti-anxiety) …
Parathyroid hormone
Parathyroid hormone (PTH) is a single-chain polypeptide composed of 84 amino acids. Available as Preotact, it is an identical form of human recombinant hormome which produced as a fusion protein undergoeing post-translational processing involving the cleavage of the OmpA leader sequence, leaving the mature protein as a single-chain 84 amino-acids...
Approved
Investigational
Matched Description: … Preos is a registered trade mark owned by NPS Pharmaceuticals, Inc. ... Parathyroid hormone (PTH) is a single-chain polypeptide composed of 84 amino acids. ... Available as Preotact, it is an identical form of human recombinant hormome which produced as a fusion …
Felodipine
Felodipine is a long-acting 1,4-dihydropyridine calcium channel blocker (CCB)b. It acts primarily on vascular smooth muscle cells by stabilizing voltage-gated L-type calcium channels in their inactive conformation. By inhibiting the influx of calcium in smooth muscle cells, felodipine prevents calcium-dependent myocyte contraction and vasoconstriction. Felodipine is the most potent CCB...
Approved
Investigational
Matched Description: … Felodipine is a long-acting 1,4-dihydropyridine calcium channel blocker (CCB)b. ... In addition to binding to L-type calcium channels, felodipine binds to a number of calcium-binding proteins …
Levetiracetam
Levetiracetam is a drug within the pyrrolidine class that is used to treat various types of seizures stemming from epileptic disorders. It was first approved for use in the United States in 1999 and is structurally and mechanistically unrelated to other anti-epileptic drugs (AEDs).[L8606,L8600,L8615] Levetiracetam possesses a wide therapeutic index[L8615,A185918]...
Approved
Matched Description: … indexes and a propensity for involvement in drug interactions. ... Levetiracetam is a drug within the pyrrolidine class that is used to treat various types of seizures ... [L8606,L8600,L8615] Levetiracetam possesses a wide therapeutic index[L8615,A185918] and little-to-no …
rsPSMA Vaccine
Prostate-specific membrane antigen (PSMA) is an ∼100 kDa transmembrane glycoprotein that is abundantly and preferentially expressed in prostate cancer, including recurrent and hormone-refractory cases. rsPSMA Vaccine is a subunit vaccine based on a novel rsPSMA protein that represents the entire extracellular domain of PSMA (Schulke et al., PNAS 100:12590, 2003)....
Approved
Investigational
Matched Description: … subunit vaccine based on a novel rsPSMA protein that represents the entire extracellular domain of PSMA ... preferentially expressed in prostate cancer, including recurrent and hormone-refractory cases. rsPSMA Vaccine is a …
Dermatophagoides farinae
Dermatophagoides farinae extracts are sterile solutions used for intradermal testing or subcutaneous immunotherapy. This combination is approved for as a year-round, once-a-day tablet that's dissolved under the tongue as a treatment for dust mite allergies.
Approved
Matched Description: … This combination is approved for as a year-round, once-a-day tablet that's dissolved under the tongue ... as a treatment for dust mite allergies. …
Poliovirus type 1 antigen (formaldehyde inactivated)
Poliovirus type 1 antigen is a suspension of poliovirus Type 1 (Mahoney) used in the active immunization of infants (as young as 6 weeks of age), children, and adults for the prevention of poliomyelitis caused by poliovirus Type 1. The vaccine contains purified and inactivated poliovirus type 1 that were...
Approved
Investigational
Matched Description: … Poliovirus type 1 antigen is a suspension of poliovirus Type 1 (Mahoney) used in the active immunization ... The vaccine contains purified and inactivated poliovirus type 1 that were grown from a continuous line …
Poliovirus type 2 antigen (formaldehyde inactivated)
Poliovirus type 2 antigen is a suspension of poliovirus Type 2 (MEF-1) used in the active immunization of infants (as young as 6 weeks of age), children, and adults for the prevention of poliomyelitis caused by poliovirus Type 2. The vaccine contains purified and inactivated poliovirus type 2 that were...
Approved
Investigational
Matched Description: … Poliovirus type 2 antigen is a suspension of poliovirus Type 2 (MEF-1) used in the active immunization ... The vaccine contains purified and inactivated poliovirus type 2 that were grown from a continuous line …
Poliovirus type 3 antigen (formaldehyde inactivated)
Poliovirus type 3 antigen is a suspension of poliovirus Type 3 (Saukett) used in the active immunization of infants (as young as 6 weeks of age), children, and adults for the prevention of poliomyelitis caused by poliovirus Type 3. The vaccine contains purified and inactivated poliovirus type 3 that were...
Approved
Investigational
Matched Description: … Poliovirus type 3 antigen is a suspension of poliovirus Type 3 (Saukett) used in the active immunization ... The vaccine contains purified and inactivated poliovirus type 3 that were grown from a continuous line …
Hydroxyzine
Hydroxyzine is a first-generation histamine H1-receptor antagonist of the dephenylmethane and piperazine classes that exhibits sedative, anxiolytic, and antiemetic properties.[A1257,A187589] It was first developed in 1955, and has since remained a relatively common treatment for allergic conditions such as pruritus, urticaria, dermatoses, and histamine-mediated pruritus. The active metabolite of hydroxyzine,...
Approved
Matched Description: … Hydroxyzine is a first-generation histamine H1-receptor antagonist of the dephenylmethane ... [A1257,A187589] It was first developed in 1955,[A189726] and has since remained a relatively common treatment …
Tetrofosmin
Tetrofosmin was developed to overcome the non-target uptake of radioligands by the generation of hetero-atomic compounds. It presents a molecular formula of 1,2-bis(bis(2-ethoxyethyl)phosphino)ethane. Tetrofosmin is part of the group of diphosphines. Tetrofosmin is used in conjunction with technetium Tc-99m as a radiopharmaceutical.
Approved
Matched Description: … It presents a molecular formula of 1,2-bis(bis(2-ethoxyethyl)phosphino)ethane. ... Tetrofosmin is used in conjunction with technetium Tc-99m as a radiopharmaceutical.[A7788] …
Givosiran
Givosiran is a small interfering RNA (siRNA) directed towards 5-aminolevulinic acid synthase, a critical enzyme in the heme biosynthesis pathway. It is manufactured by Alnylam Pharmaceuticals and was first approved for use in the United States in November 2019 for the treatment of adults with acute hepatic porphyria, a genetic...
Approved
Investigational
Matched Description: … Givosiran is a small interfering RNA (siRNA) directed towards 5-aminolevulinic acid synthase, a critical ... use in the United States in November 2019 for the treatment of adults with acute hepatic porphyria, a ... Givosiran is the second-ever FDA-approved member of the siRNA drug class (the first being [patisiran]), a …
Bacillus calmette-guerin substrain tice live antigen
Bacillus calmette-guerin substrain tice live antigen is a vaccine containing attenuated live culture preparation of the Bacillus of Calmette and Guerin (BCG) strain of Mycobacterium bovis for percutaneous use. It is administered to prevent the development of tuberculosis.
Approved
Matched Description: … Bacillus calmette-guerin substrain tice live antigen is a vaccine containing attenuated live culture …
Japanese Encephalitis Vaccine, Inactivated, Adsorbed
Approved
Investigational
Lavender oil
Approved
Experimental
Diaminopyrimidine oxide
Diaminopyrimidine oxide is a compound similar to minoxidil which is used to aid in hair growth.
Approved
Matched Description: … Diaminopyrimidine oxide is a compound similar to [minoxidil] which is used to aid in hair growth. …
Betaxolol
A cardioselective beta-1-adrenergic antagonist with no partial agonist activity.
Approved
Investigational
Matched Description: … A cardioselective beta-1-adrenergic antagonist with no partial agonist activity. …
Chlorothiazide
A thiazide diuretic with actions and uses similar to those of hydrochlorothiazide. (From Martindale, The Extra Pharmacopoeia, 30th ed, p812)
Approved
Vet approved
Matched Description: … A thiazide diuretic with actions and uses similar to those of hydrochlorothiazide. …
Bezlotoxumab
Bezlotoxumab is a fully humanized ImmunoglobulinG1 (IgG1) kappa monoclonal antibody that binds to Clostridium difficile toxin B and neutralizes its effects. First approved by the FDA on October 21, 2016, bezlotoxumab is used to reduce the recurrence of C. difficile infection. On November 22, 2016, the Committee for Medicinal Products...
Approved
Investigational
Matched Description: … Bezlotoxumab is a fully humanized ImmunoglobulinG1 (IgG1) kappa monoclonal antibody that binds to _Clostridium ... Committee for Medicinal Products for Human Use of the European Medicines Agency recommended the granting of a …
Buclizine
Buclizine is an antihistamine medication with both antiemetic and anticholinergic effects , belonging to the piperazine derivative family of drugs. It was manufactured by Stuart Pharms and initially approved by the FDA in 1957. Following this, it was touted to be effective as an appetite stimulant in children when administered...
Approved
Human papillomavirus type 11 L1 capsid protein antigen
Human papillomavirus type 11 L1 capsid protein antigen is contained in Gardasil, or a recombinant Human Papillomavirus Quadrivalent (Types 6, 11, 16, and 18) vaccine for intramuscular injection. It is an immunization for young men and women 9-26 years of age for the prevention of diseases caused by Human Papillomavirus...
Approved
Matched Description: … Human papillomavirus type 11 L1 capsid protein antigen is contained in Gardasil, or a recombinant Human …
Displaying drugs 1051 - 1075 of 11782 in total