Displaying drugs 10951 - 10975 of 12071 in total
Levodropropizine
Levodropropizine is under investigation in clinical trial NCT01573663 (A Drug-Drug Interaction Study of Ambroxol and Levodropropizine).
Investigational
Matched Description: … Levodropropizine is under investigation in clinical trial NCT01573663 (A Drug-Drug Interaction Study …
ST101 peptide
ST101 is a cell-penetrating peptide that disrupts the protein-protein interactions driving ATF5-regulated gene transcription.
Investigational
Matched Description: … ST101 is a cell-penetrating peptide that disrupts the protein-protein interactions driving ATF5-regulated …
tgAAG-76
tgAAG-76 consists of a recombinant adeno-associated virus (serotype 2) (rAAV2) gene transfer agent expressing RPE65.
Investigational
Matched Description: … tgAAG-76 consists of a recombinant adeno-associated virus (serotype 2) (rAAV2) gene transfer agent expressing …
Pemtumomab
Pemtumomab is a murine monoclonal antibody radiolabeled with Yttrium-90. It targets the mucin 1 (MUC1) protein.
Investigational
Matched Description: … Pemtumomab is a murine monoclonal antibody radiolabeled with Yttrium-90. …
Matuzumab
Matuzumab (formerly known as the experimental drug, EMD 72000) is a humanized monoclonal antibody used in cancer treatment. It has a high affinity for EGFR (epithelial growth factor receptor), frequently associated with the growth of blood vessels in malignancy, facilitating tumor growth and survival.
Investigational
Matched Description: … Matuzumab (formerly known as the experimental drug, EMD 72000) is a humanized monoclonal antibody used ... It has a high affinity for EGFR (epithelial growth factor receptor), frequently associated with the growth …
rGLP-1
rGLP-1 is a continuous infusion of glucagon-like peptide 1, or GLP-1, targeted for the treatment of congestive heart failure (CHF) in patients ineligible for transplant. GLP-1 is a naturally occurring hormone produced in the intestines in response to food intake.
Investigational
Matched Description: … GLP-1 is a naturally occurring hormone produced in the intestines in response to food intake. ... rGLP-1 is a continuous infusion of glucagon-like peptide 1, or GLP-1, targeted for the treatment of congestive …
Ertiprotafib
Ertiprotafib belongs to a novel class of insulin sensitizers developed for treatment of type 2 diabetes. In insulin-resistant rodent models, ertiprotafib and a close analog lowered both fasting blood glucose and insulin levels and improved glycemic excursion during an oral glucose tolerance test.
Investigational
Matched Description: … Ertiprotafib belongs to a novel class of insulin sensitizers developed for treatment of type 2 diabetes ... In insulin-resistant rodent models, ertiprotafib and a close analog lowered both fasting blood glucose …
Gemogenovatucel-T
Gemogenovatucel-T is a bi-shRNA furin/Granulocyte Macrophage Colony Stimulating Factor (GMCSF) Augmented autologous tumour cell vaccine. Furin is a convertase involved in the activation of TGFβ-1 and TGFβ-2. Gemogenovatucel-T is being investigated in the treatment of various cancers.
Investigational
Matched Description: … Furin is a convertase involved in the activation of TGFβ-1 and TGFβ-2. ... Gemogenovatucel-T is a bi-shRNA furin/Granulocyte Macrophage Colony Stimulating Factor (GMCSF) Augmented …
CAM-2029
CAM2029 is a new ready-to-use, long-acting octreotide formulation being developed for the long-term treatment of acromegaly, carcinoid syndrome and vasoactive intestinal peptide (VIP)-producing tumours. CAM2029 was found to provide long-acting release of octreotide resulting in a statistically significant suppression of a clinical biomarker insulin-like growth factor 1 (IGF-1) over the...
Investigational
Matched Description: … CAM2029 is a new ready-to-use, long-acting octreotide formulation being developed for the long-term treatment ... CAM2029 was found to provide long-acting release of octreotide resulting in a statistically significant ... suppression of a clinical biomarker insulin-like growth factor 1 (IGF-1) over the target one-month therapeutic …
Interferon Kappa
Interferon kappa is a subclass of type I interferon mediating host defence which consists of 207 amino acids and has 30% homology with others of the same class as it consists of a series of cysteine and a 27-amino acid signal peptide conserved in type I interferons. This gene encoding...
Investigational
Matched Description: … a 27-amino acid signal peptide conserved in type I interferons. ... Interferon kappa is a subclass of type I interferon mediating host defence which consists of 207 amino ... acids and has 30% homology with others of the same class as it consists of a series of cysteine and …
MK-0731
MK-0731 is a kinesin spindle protein inhibitor and antineoplastic agent.
Experimental
Matched Description: … MK-0731 is a kinesin spindle protein inhibitor and antineoplastic agent. …
CA-170
CA-170 is a selective, small molecule inhibitor of PD-L1.
Investigational
Matched Description: … CA-170 is a selective, small molecule inhibitor of PD-L1. …
LAVA-051
LAVA-051 is a humanized Vγ9Vδ2-T cell-engaging bispecific antibody.
Investigational
Matched Description: … LAVA-051 is a humanized Vγ9Vδ2-T cell-engaging bispecific antibody. …
Galactose-uridine-5'-diphosphate
A nucleoside diphosphate sugar which can be epimerized into UDPglucose for entry into the mainstream of carbohydrate metabolism. Serves as a source of galactose in the synthesis of lipopolysaccharides, cerebrosides, and lactose.
Experimental
Matched Description: … A nucleoside diphosphate sugar which can be epimerized into UDPglucose for entry into the mainstream ... Serves as a source of galactose in the synthesis of lipopolysaccharides, cerebrosides, and lactose. …
Mitoquinone
Mitoquinone is based on a novel technology, targeted lipophilic cations, that transport and concentrate antioxidants into the mitochondria -- organelles inside cells that provide energy for life processes -- where they accumulate up to a thousand fold. In 2004, a genomic study of hereditary early-onset Parkinson's disease demonstrated a direct...
Investigational
Matched Description: … In 2004, a genomic study of hereditary early-onset Parkinson's disease demonstrated a direct molecular ... Mitoquinone is based on a novel technology, targeted lipophilic cations, that transport and concentrate ... mitochondria -- organelles inside cells that provide energy for life processes -- where they accumulate up to a …
Drinabant
AVE-1625 is an oral selective and potent antagonist of cannabinoid 1 (CB1) receptors having the same mechanism of action as rimonabant. It is currently developed in obesity and its associated comorbidities. AVE-1625 is also being developed for the treatment of Alzheimer disease.
Investigational
PRX-07034
Investigational
MLN8054
MLN8054 has been used in trials studying the treatment of Colon Neoplasm, Breast Neoplasm, Bladder Neoplasm, Pancreatic Neoplasm, and Advanced Malignancies.
Investigational
Thymidine
Thymidine is a pyrimidine deoxynucleoside. Thymidine is the DNA nucleoside T, which pairs with deoxyadenosine (A) in double-stranded DNA. In cell biology it is used to synchronize the cells in S phase.
Experimental
Investigational
Matched Description: … Thymidine is a pyrimidine deoxynucleoside. ... Thymidine is the DNA nucleoside T, which pairs with deoxyadenosine (A) in double-stranded DNA. …
beta-Naphthoflavone
β-Naphthoflavone, also known as 5,6-benzoflavone, is a potent agonist of the aryl hydrocarbon receptor and induces cytochromes P450 (CYPs) and uridine 5'-diphospho-glucuronosyltransferases (UGTs). It may be a chemopreventive agent.
Experimental
Matched Description: … It may be a chemopreventive agent. ... β-Naphthoflavone, also known as 5,6-benzoflavone, is a potent agonist of the aryl hydrocarbon receptor …
Ronacaleret
Ronacaleret is a calcium-sensing receptor antagonist.
Investigational
Matched Description: … Ronacaleret is a calcium-sensing receptor antagonist. …
Ciluprevir
The compound, named BILN 2061, is an orally active inhibitor of the HCV NS3 protease and the first member of this new drug class to be tested in humans.
Investigational
Displaying drugs 10951 - 10975 of 12071 in total