Displaying drugs 11026 - 11050 of 12185 in total
SVV-001
SVV-001 is investigated for use/treatment in cancer/tumors and lung cancer. SVV-001 is a solid. SVV-001 (Seneca Valley Virus) is a novel native picornavirus being developed as a systemically deliverable oncolytic virus for treatment of human cancers with neuroendocrine features. SVV-001 has also demonstrated cancer-killing specificity 10,000 times higher than that...
Investigational
Matched Description: … SVV-001 is a solid. ... SVV-001 (Seneca Valley Virus) is a novel native picornavirus being developed as a systemically deliverable …
GS-441524
GS-441524 is an adenosine nucleotide analog antiviral, similar to remdesivir.[A203057,L13239] This molecule was patented in 2009. In vitro studies of GS-441524 have determined it has a higher EC50 than remdesivir against a number of viruses, meaning GS-441524 is less potent.[A203057,A203057] GS-441524 continues to be studied in the treatment of Feline...
Experimental
Matched Description: … against a number of viruses, meaning GS-441524 is less potent. ... [L13775] _In vitro_ studies of GS-441524 have determined it has a higher EC50 than remdesivir ... A203057] GS-441524 continues to be studied in the treatment of Feline Infectious Peritonitis Virus, a …
Bamet-UD2
Bamet-UD2 is a novel bile acid-platinum derivative.
Experimental
Matched Description: … Bamet-UD2 is a novel bile acid-platinum derivative. …
Pidotimod
Pidotimod is a synthetic dipeptide with immunomodulatory properties.
Experimental
Matched Description: … Pidotimod is a synthetic dipeptide with immunomodulatory properties.[A7956] …
SB-218078
SB-218078 is a specific inhibitor of CHK1.
Investigational
Matched Description: … SB-218078 is a specific inhibitor of CHK1.[A253117] …
IMAB027
IMAB027 is a chimeric monoclonal antibody against Claudin 6.
Investigational
Matched Description: … IMAB027 is a chimeric monoclonal antibody against Claudin 6. …
BSK02
BSK02 is a Sperm Protein-17 oral microparticle vaccine
Investigational
Matched Description: … BSK02 is a Sperm Protein-17 oral microparticle vaccine …
BBT-059
BBT-059 is a long-acting interleukin-11 analog.
Investigational
Matched Description: … BBT-059 is a long-acting interleukin-11 analog. …
CPO-107
CPO-107 is a CD20-CD47 bispecific fusion protein
Investigational
Matched Description: … CPO-107 is a CD20-CD47 bispecific fusion protein …
Fobrepodacin
Investigational
D-Treitol
A four-carbon sugar that is found in algae, fungi, and lichens. It is twice as sweet as sucrose and can be used as a coronary vasodilator. [PubChem]
Experimental
Matched Description: … A four-carbon sugar that is found in algae, fungi, and lichens. ... It is twice as sweet as sucrose and can be used as a coronary vasodilator. [PubChem] …
CZEN 002
CZEN-002 is a novel, non-azole anti-fungal synthetic octapeptide, derived from alpha-Melanocyte-Stimulating Hormone (a-MSH). CZEN-002 modulates inflammatory and immune responses. It has also been shown to kill Candida albicans (C. albicans), a single-celled fungal organism that causes a variety of infections, including vaginitis. This organism can invade tissues and produce fatal...
Investigational
Matched Description: … Hormone (a-MSH). ... a variety of infections, including vaginitis. ... It appears that CZEN-002 works on a receptor in yeast that has yet to be identified. …
VSF-173
VSF-173 is an oral small molecule. It is an oral compound that has demonstrated effects on animal sleep/wake patterns and gene expression patterns suggestive of a stimulant effect. It is developed for the treatment of excessive sleepiness. Study shows that VSF-173 possesses a novel mechanism to address disorders of excessive...
Investigational
Matched Description: … Study shows that VSF-173 possesses a novel mechanism to address disorders of excessive sleepiness. ... that has demonstrated effects on animal sleep/wake patterns and gene expression patterns suggestive of a …
Brifentanil
Brifentanil (also known as A-3331) is an analog of fentanyl, a potent opioid. This drug is classified as an opioid analgesic and was developed in the early 1990s. The effects of brifentanil are very similar to those of alfentanil, with strong but short lasting analgesia and sedation, and particularly notable...
Illicit
Matched Description: … Brifentanil (also known as A-3331) is an analog of fentanyl, a potent opioid. …
GSK-945237
GSK-945237 is under investigation in clinical trial NCT01039610 (A Single Center Four Part Study in Healthy Adult Subjects to Evaluate: the Safety, Tolerability and Pharmacokinetics of a Single Oral Dose and Repeat Escalating Oral Doses of GSK945237; the Effect of Linezolid on Hematology Safety Parameters; and the Effects of GSK945237...
Investigational
Matched Description: … GSK-945237 is under investigation in clinical trial NCT01039610 (A Single Center Four Part Study in Healthy ... Adult Subjects to Evaluate: the Safety, Tolerability and Pharmacokinetics of a Single Oral Dose and …
XL019
XL019 is a selective inhibitor of the cytoplasmic tyrosine kinase JAK2. An IND for XL019 was filed by Exelixis in May 2007.
Investigational
Matched Description: … XL019 is a selective inhibitor of the cytoplasmic tyrosine kinase JAK2. …
Succinobucol
AGI-1067, is a novel small molecule with anti-oxidant and anti-inflammatory properties that was discovered by AtheroGenics and designed to treat atherosclerosis of the blood vessels of the heart, or coronary artery disease.
Investigational
Matched Description: … AGI-1067, is a novel small molecule with anti-oxidant and anti-inflammatory properties that was discovered …
Merimepodib
Merimepodib (VX-497) is a novel noncompetitive inhibitor of IMPDH. Merimepodib is orally bioavailable and inhibits the proliferation of primary human, mouse, rat, and dog lymphocytes at concentrations of approximately 100 nM.
Investigational
Matched Description: … Merimepodib (VX-497) is a novel noncompetitive inhibitor of IMPDH. …
LY2181308
LY2181308 is investigated in clinical trials for treating solid tumors. LY2181308 is a solid. LY2181308 is directed against a molecular target called survivin. LY2181308 is known to target baculoviral IAP repeat-containing protein 5. LY2181308 is an anti-sense oligonucleotide that potently downregulated survivin expression in human cancer cells derived from lung,...
Investigational
Matched Description: … LY2181308 is a solid. LY2181308 is directed against a molecular target called survivin. …
Erythritol
Erythritol is a four-carbon sugar that is found in algae, fungi, and lichens. It is twice as sweet as sucrose and can be used as a coronary vasodilator.
Experimental
Matched Description: … Erythritol is a four-carbon sugar that is found in algae, fungi, and lichens. ... It is twice as sweet as sucrose and can be used as a coronary vasodilator. …
Eritoran
Eritoran is a structural analogue of the lipid A portion of lipopolysaccharide (LPS). It is being developed by Eisai Research Institute of Boston for the treatment of severe sepsis.
Investigational
Matched Description: … Eritoran is a structural analogue of the lipid A portion of lipopolysaccharide (LPS). …
1-(3-bromophenyl)-7-chloro-6-methoxy-3,4-dihydroisoquinoline
1-(3-bromophenyl)-7-chloro-6-methoxy-3,4-dihydroisoquinoline is a solid. This compound belongs to the isoquinolines and derivatives. These are aromatic polycyclic compounds containing an isoquinoline moiety, which consists of a benzene ring fused to a pyridine ring and forming benzo[c]pyridine. This medication is known to target mitogen-activated protein kinase 10.
Experimental
Matched Description: … ring fused to a pyridine ring and forming benzo[c]pyridine. ... 1-(3-bromophenyl)-7-chloro-6-methoxy-3,4-dihydroisoquinoline is a solid. ... These are aromatic polycyclic compounds containing an isoquinoline moiety, which consists of a benzene …
5-methoxy-N,N-dimethyltryptamine
5-methoxy-N,N-dimethyltryptamine (5-MeO-DMT) is a tryptamine with psychedelic properties. It is found in a wide variety of plant species, and a single psychoactive toad species, the Colorado River toad. This drug, as well as dimethyltryptamine and bufotenin, have been registered to be used in South America in religious and spiritual rituals.
Experimental
Illicit
Matched Description: … It is found in a wide variety of plant species, and a single psychoactive toad species, the Colorado ... 5-methoxy-N,N-dimethyltryptamine (5-MeO-DMT) is a tryptamine with psychedelic properties. …
Displaying drugs 11026 - 11050 of 12185 in total