Displaying drugs 1151 - 1175 of 15670 in total
Clodronic acid
Clodronic acid is a first generation bisphosphonate similar to etidronic acid and tiludronic acid. These drugs were developed to mimic the action of pyrophosphate, a regulator of calcification and decalcification. clodronate’s use has decreased over the years in favor of the third generation, nitrogen containing bisphosphonate zoledronic acid, ibandronic acid,...
Approved
Investigational
Vet approved
Matched Description: … [A203111]
Clodronic acid is not FDA approved, but is approved in Canada.[L13910] ... Clodronic acid is a first generation bisphosphonate similar to [etidronic acid] and [tiludronic acid] ... [A203111] These drugs were developed to mimic the action of pyrophosphate, a regulator of calcification …
Matched Categories: … Drugs for Treatment of Bone Diseases …
Matched Categories: … Drugs for Treatment of Bone Diseases …
Perboric acid
Perboric acid is mainly found in its salt form of sodium perborate and it can be found as a monohydrate or tetrahydrate. It is one of the peroxy acid salts with very wide functionalities in industrial settings. Perboric acid in the form of sodium perborate is approved by Health Canada...
Approved
Matched Description: … Perboric acid is mainly found in its salt form of sodium perborate and it can be found as a monohydrate ... as a disinfectant of medical instruments. ... [L1113] By the FDA, sodium perborate is approved as an ointment for the protection of poison ivy dermatitis …
Matched Categories: … Antiinfectives and Antiseptics for Local Oral Treatment …
Matched Categories: … Antiinfectives and Antiseptics for Local Oral Treatment …
Bacillus calmette-guerin substrain tice live antigen
Bacillus calmette-guerin substrain tice live antigen is a vaccine containing attenuated live culture preparation of the Bacillus of Calmette and Guerin (BCG) strain of Mycobacterium bovis for percutaneous use. It is administered to prevent the development of tuberculosis.
Approved
Matched Description: … Bacillus calmette-guerin substrain tice live antigen is a vaccine containing attenuated live culture ... preparation of the Bacillus of Calmette and Guerin (BCG) strain of *Mycobacterium bovis* for percutaneous …
Sulconazole
Sulconazole, brand name Exelderm, is a broad-spectrum anti-fungal agent available as a topical cream and solution. Sulconazole nitrate, the active ingredient, is an imidazole derivative that inhibits the growth of common pathogenic dermatophytes, making it an effective treatment for tinea cruris and tinea corporis infections.[L44592,L44597] Sulconazole appears to be effective...
Approved
Matched Iupac: … 1-(2-{[(4-chlorophenyl)methyl]sulfanyl}-2-(2,4-dichlorophenyl)ethyl)-1H-imidazole …
Matched Description: … Sulconazole, brand name Exelderm, is a broad-spectrum anti-fungal agent available as a topical cream ... [L44592,L44597] Sulconazole appears to be effective and well-tolerated in the treatment of superficial ... derivative that inhibits the growth of common pathogenic dermatophytes, making it an effective treatment for …
Matched Categories: … Antifungals for Topical Use ... Antifungals for Dermatological Use …
Matched Description: … Sulconazole, brand name Exelderm, is a broad-spectrum anti-fungal agent available as a topical cream ... [L44592,L44597] Sulconazole appears to be effective and well-tolerated in the treatment of superficial ... derivative that inhibits the growth of common pathogenic dermatophytes, making it an effective treatment for …
Matched Categories: … Antifungals for Topical Use ... Antifungals for Dermatological Use …
Clozapine
Clozapine is a tricyclic dibenzodiazepine, classified as an atypical antipsychotic agent. Clozapine displays affinity to various neuroreceptors with a particularly low affinity to the dopamine receptors, thus breaking the mold of first-generation antipsychotics and deeming it "atypical". . This low affinity to dopamine receptors results in fewer extrapyramidal side effects,...
Approved
Matched Description: … [A256718]
Clozapine was approved by the FDA in 1989 for treatment-resistant schizophrenia under the ... was briefly removed from the market in various jurisdictions in 1970 due to severe agranulocytosis. ... Clozapine is a tricyclic dibenzodiazepine, classified as an atypical antipsychotic agent. …
Matched Categories: … Heterocyclic Compounds, 3-Ring …
Matched Categories: … Heterocyclic Compounds, 3-Ring …
Daridorexant
Daridorexant, formerly known as nemorexant, is a selective dual orexin receptor antagonist used to treat insomnia. Insomnia is characterized by difficulties with sleep onset and/or sleep maintenance and impairment of daytime functioning. It chronically affects the person's daily functioning and long-term health effects, as insomnia is often associated with comorbidities...
Approved
Matched Iupac: … 5-chloro-2-[(2S)-1-[5-methoxy-2-(2H-1,2,3-triazol-2-yl)benzoyl]-2-methylpyrrolidin-2-yl]-4-methyl-1H- …
Matched Description: … Conventional treatments for insomnia include drugs targeting gamma-aminobutyric acid type-A (GABA-A), ... [A244280] Daridorexant was approved by the European Commission on May 3, 2022, as the first dual orexin ... sleep and daytime functioning in patients with insomnia. …
Matched Description: … Conventional treatments for insomnia include drugs targeting gamma-aminobutyric acid type-A (GABA-A), ... [A244280] Daridorexant was approved by the European Commission on May 3, 2022, as the first dual orexin ... sleep and daytime functioning in patients with insomnia. …
Haemagglutinin-strain B (Victoria-like)
Approved
Matched Mixtures name: … Afluria Tetra Injektionssuspension in einer Fertigspritze …
Miglitol
Miglitol inhibits the breakdown complex carbohydrates into glucose. It is primarily used in diabetes mellitus type 2 for establishing greater glycemic control by preventing the digestion of carbohydrates (such as disaccharides, oligosaccharides, and polysaccharides) into monosaccharides which can be absorbed by the body.
Miglitol should be taken at the start...
Approved
Matched Iupac: … (2R,3R,4R,5S)-1-(2-hydroxyethyl)-2-(hydroxymethyl)piperidine-3,4,5-triol …
Matched Description: … It is primarily used in diabetes mellitus type 2 for establishing greater glycemic control by preventing ... Miglitol should be taken at the start of a meal for maximal effect and the effect will depend on the ... amount of poly and oligosaccharides in the diet. …
Matched Categories: … Drugs Used in Diabetes …
Matched Description: … It is primarily used in diabetes mellitus type 2 for establishing greater glycemic control by preventing ... Miglitol should be taken at the start of a meal for maximal effect and the effect will depend on the ... amount of poly and oligosaccharides in the diet. …
Matched Categories: … Drugs Used in Diabetes …
Nabilone
Nabilone (marketed as Cesamet) is a synthetic form of delta-9-tetrahydrocannabinol (Δ⁹-THC), the primary psychoactive component of cannabis (marijuana). Although structurally distinct from THC, nabilone mimics THC's structure and pharmacological activity through weak partial agonist activity at Cannabinoid-1 (CB1R) and Cannabinoid-2 (CB2R) receptors, however it is considered to be twice as...
Approved
Investigational
Matched Iupac: … (6aR,10aR)-1-hydroxy-6,6-dimethyl-3-(2-methyloctan-2-yl)-6H,6aH,7H,8H,9H,10H,10aH-benzo[c]isochromen- …
Matched Description: … for such a wide variety of medical conditions. ... It is also approved for use in treatment of anorexia and weight loss in patients with AIDS. ... pharmacological activity through weak partial agonist activity at Cannabinoid-1 (CB1R) and Cannabinoid-2 …
Matched Description: … for such a wide variety of medical conditions. ... It is also approved for use in treatment of anorexia and weight loss in patients with AIDS. ... pharmacological activity through weak partial agonist activity at Cannabinoid-1 (CB1R) and Cannabinoid-2 …
Oxyquinoline
Oxyquinoline is a heterocyclic phenol and derivative of quinoline with antiseptic, disinfectant, and pesticide properties. It is used as a stabilizer for hydrogen peroxide, where it is sometimes added in cosmetic products.
Approved
Vet approved
Matched Description: … It is used as a stabilizer for hydrogen peroxide, where it is sometimes added in cosmetic products. ... Oxyquinoline is a heterocyclic phenol and derivative of quinoline with antiseptic, disinfectant, and …
Matched Mixtures name: … INDIO (111-IN) OSSINA CURIUM NETHERLANDS …
Matched Categories: … Heterocyclic Compounds, 2-Ring ... Antiinfectives and Antiseptics for Local Oral Treatment …
Matched Mixtures name: … INDIO (111-IN) OSSINA CURIUM NETHERLANDS …
Matched Categories: … Heterocyclic Compounds, 2-Ring ... Antiinfectives and Antiseptics for Local Oral Treatment …
Golodirsen
Golodirsen is a morpholino antisense oligomer designed to treat about 8% of patients with Duchenne Muscular Dystrophy (DMD). This is an X-linked condition leading to progressive muscle degeneration that begins in early childhood, rendering many patients wheelchair-bound by age 12. Often, patients succumb to this condition by age 30 or...
Approved
Matched Description: … this drug in patients suffering from a certain form of DMD. ... [A188580,T756] A similar drug used in the treatment of other types of DMD is [eteplirsen], which targets ... a different genetic mutation. …
Matched Categories: … Compounds used in a research, industrial, or household setting …
Matched Categories: … Compounds used in a research, industrial, or household setting …
Naldemedine
Naldemedine is an opioid receptor antagonist [FDA Label]. It is a modified form of DB00704 to which a side chain has been added to increase molecular weight and polar surface area resulting in restricted transport across the blood brain barrier. Naldemedine was approved in 2017 in both the US and...
Approved
Investigational
Matched Iupac: … (1S,5R,13R,17S)-4-(cyclopropylmethyl)-10,14,17-trihydroxy-N-[2-(3-phenyl-1,2,4-oxadiazol-5-yl)propan- ... 2-yl]-12-oxa-4-azapentacyclo[9.6.1.0^{1,13}.0^{5,17}.0^{7,18}]octadeca-7,9,11(18),14-tetraene-15-carboxamide …
Matched Description: … Naldemedine was approved in 2017 in both the US and Japan for the treatment of Opioid-induced Constipation ... It is a modified form of [DB00704] to which a side chain has been added to increase molecular weight ... and polar surface area resulting in restricted transport across the blood brain barrier. …
Matched Salts cas: … 1345728-04-2 …
Matched Categories: … Drugs for Constipation …
Matched Description: … Naldemedine was approved in 2017 in both the US and Japan for the treatment of Opioid-induced Constipation ... It is a modified form of [DB00704] to which a side chain has been added to increase molecular weight ... and polar surface area resulting in restricted transport across the blood brain barrier. …
Matched Salts cas: … 1345728-04-2 …
Matched Categories: … Drugs for Constipation …
Abemaciclib
Abemaciclib is an antitumor agent and dual inhibitor of cyclin-dependent kinases 4 (CDK4) and 6 (CDK6) that are involved in the cell cycle and promotion of cancer cell growth in case of unregulated activity. On September 28, 2017, FDA granted approval of abemaciclib treatment under the market name Verzenio for...
Approved
Investigational
Matched Iupac: … N-{5-[(4-ethylpiperazin-1-yl)methyl]pyridin-2-yl}-5-fluoro-4-[4-fluoro-2-methyl-1-(propan-2-yl)-1H-1,3 ... -benzodiazol-6-yl]pyrimidin-2-amine …
Matched Description: … On September 28, 2017, FDA granted approval of abemaciclib treatment under the market name Verzenio for ... of cancer, or in combination with [DB00947]. ... the cell cycle and promotion of cancer cell growth in case of unregulated activity. …
Matched Categories: … MATE 2 Inhibitors ... Heterocyclic Compounds, 2-Ring ... MATE 1 Substrates with a Narrow Therapeutic Index ... P-glycoprotein substrates with a Narrow Therapeutic Index ... Cytochrome P-450 CYP3A4 Substrates with a Narrow Therapeutic Index …
Matched Description: … On September 28, 2017, FDA granted approval of abemaciclib treatment under the market name Verzenio for ... of cancer, or in combination with [DB00947]. ... the cell cycle and promotion of cancer cell growth in case of unregulated activity. …
Matched Categories: … MATE 2 Inhibitors ... Heterocyclic Compounds, 2-Ring ... MATE 1 Substrates with a Narrow Therapeutic Index ... P-glycoprotein substrates with a Narrow Therapeutic Index ... Cytochrome P-450 CYP3A4 Substrates with a Narrow Therapeutic Index …
Tixocortol
Tixocortol is a 21-thiol derivative of hydrocortisone classified as a class A corticosteroid. It is a synthetic steroid with topical anti-inflammatory properties without the systemic glucocorticoid and mineralocorticoid activities and toxicity.
Approved
Withdrawn
Matched Iupac: … (1S,2R,10S,11S,14R,15S,17S)-14,17-dihydroxy-2,15-dimethyl-14-(2-sulfanylacetyl)tetracyclo[8.7.0.0²,⁷.0¹¹,¹⁵ …
Matched Description: … Tixocortol is a 21-thiol derivative of hydrocortisone classified as a class A corticosteroid. ... It is a synthetic steroid with topical anti-inflammatory properties without the systemic glucocorticoid …
Matched Description: … Tixocortol is a 21-thiol derivative of hydrocortisone classified as a class A corticosteroid. ... It is a synthetic steroid with topical anti-inflammatory properties without the systemic glucocorticoid …
Hexocyclium
Hexocyclium is a muscarinic acetylcholine receptor antagonist which was presumably used in the treatment of gastric ulcer or diarrhea. It was once available under the tradename Tral marketed by Abbvie Inc. but has been discontinued. Proton pump inhibitors like DB00338 and opiate anti-diarrheal agents like DB00836 have largely replaced the...
Approved
Matched Iupac: … 4-(2-cyclohexyl-2-hydroxy-2-phenylethyl)-1,1-dimethylpiperazin-1-ium …
Matched Description: … Hexocyclium is a muscarinic acetylcholine receptor antagonist which was presumably used in the treatment ... ] and opiate anti-diarrheal agents like [DB00836] have largely replaced the use of anti-muscarinics in …
Matched Categories: … Drugs for Functional Gastrointestinal Disorders …
Matched Description: … Hexocyclium is a muscarinic acetylcholine receptor antagonist which was presumably used in the treatment ... ] and opiate anti-diarrheal agents like [DB00836] have largely replaced the use of anti-muscarinics in …
Matched Categories: … Drugs for Functional Gastrointestinal Disorders …
Nylidrin
Nylidrin, also known as buphenine belongs to the category of drugs called vasodilators, which relax blood vessels and increase blood flow. Nylidrin is a peripheral vasodilator. Some studies show the evidence of improving cognitive impairment in selected individuals, such as geriatric patients with mild to moderate symptoms of cognitive, emotional...
Approved
Matched Iupac: … 4-{1-hydroxy-2-[(4-phenylbutan-2-yl)amino]propyl}phenol …
Matched Description: … Nylidrin is a peripheral vasodilator. ... Nylidrin is utilized to treat several disorders that may benefit from increased blood flow (for example ... Some studies show the evidence of improving cognitive impairment in selected individuals, such as geriatric …
Matched Categories: … 2-Amino-1-Phenylethanol Derivatives …
Matched Description: … Nylidrin is a peripheral vasodilator. ... Nylidrin is utilized to treat several disorders that may benefit from increased blood flow (for example ... Some studies show the evidence of improving cognitive impairment in selected individuals, such as geriatric …
Matched Categories: … 2-Amino-1-Phenylethanol Derivatives …
Lucinactant
Lucinactant is a new synthetic peptide-containing surfactant for intratracheal use. It contains sinapultide, a novel, hydrophobic, 21-amino acid peptide (leucine and lysine repeating units, KL4 peptide) designed to mimic human surfactant protein-B (SB-P). More specifically, it mimics the C-terminal amphipathic helical domain of this protein. It also consists of phospholipids...
Approved
Investigational
Matched Description: … Lucinactant is a new synthetic peptide-containing surfactant for intratracheal use. ... More specifically, it mimics the C-terminal amphipathic helical domain of this protein. ... It contains sinapultide, a novel, hydrophobic, 21-amino acid peptide (leucine and lysine repeating units …
Samarium (153Sm) lexidronam
Samarium Sm 153 lexidronam is a radioactive medication used to treat pain caused by cancer that has spread to the bone. It is a radiopharmaceutical. Radiopharmaceuticals are radioactive agents that may be used to diagnose some diseases by studying the function of the body's organs or to treat certain diseases.Samarium...
Approved
Investigational
Matched Iupac: … (153Sm)samarium(3+) ion hydrogen {[(hydrogen phosphonomethyl)({2-[(hydrogen phosphonomethyl)(phosphonomethyl …
Matched Description: … It is a radiopharmaceutical. ... The radioactive samarium is taken up in the bone cancer area and gives off radiation that helps provide ... Samarium Sm 153 lexidronam is a radioactive medication used to treat pain caused by cancer that has spread …
Matched Description: … It is a radiopharmaceutical. ... The radioactive samarium is taken up in the bone cancer area and gives off radiation that helps provide ... Samarium Sm 153 lexidronam is a radioactive medication used to treat pain caused by cancer that has spread …
Streptococcus pneumoniae type 10A capsular polysaccharide diphtheria CRM197 protein conjugate antigen
Streptococcus pneumoniae type 10A capsular polysaccharide diphtheria CRM197 protein conjugate antigen is a sterile vaccine that contains saccharides of the capsular antigens of Streptococcus pneumoniae serotype 10A individually conjugated to the CRM197 protein, a nontoxic variant of diphtheria toxin isolated from cultures of Corynebacterium diphtheriae strain C7 (β197). The saccharides...
Approved
Matched Description: … The saccharides in the vaccine are prepared from purified polysaccharides that are chemically activated ... Streptococcus pneumoniae type 10A capsular polysaccharide diphtheria CRM197 protein conjugate antigen is a ... antigens of *Streptococcus pneumoniae* serotype 10A individually conjugated to the CRM197 protein, a …
Tropisetron
Tropisetron is an indole derivative with antiemetic activity. As a selective serotonin receptor antagonist, tropisetron competitively blocks the action of serotonin at 5HT3 receptors, resulting in suppression of chemotherapy- and radiotherapy-induced nausea and vomiting.
Tropisetron appears to be well tolerated with the most frequently reported adverse effect being headache. Extrapyramidal...
Approved
Investigational
Matched Iupac: … (1R,3S,5S)-8-methyl-8-azabicyclo[3.2.1]octan-3-yl 1H-indole-3-carboxylate …
Matched Description: … As a selective serotonin receptor antagonist, tropisetron competitively blocks the action of serotonin ... at 5HT3 receptors, resulting in suppression of chemotherapy- and radiotherapy-induced nausea and vomiting …
Matched Salts cas: … 833482-77-2 …
Matched Categories: … Heterocyclic Compounds, 2-Ring …
Matched Description: … As a selective serotonin receptor antagonist, tropisetron competitively blocks the action of serotonin ... at 5HT3 receptors, resulting in suppression of chemotherapy- and radiotherapy-induced nausea and vomiting …
Matched Salts cas: … 833482-77-2 …
Matched Categories: … Heterocyclic Compounds, 2-Ring …
Oritavancin
Oritavancin is a glycopeptide antibiotic used for the treatment of skin infections. It was developed by The Medicines Company (acquired by Novartis). Oritavancin was initially approved by the FDA in 2014 and formulated to combat susceptible gram-positive bacteria that cause skin and skin structure infections. It boasts the option of...
Approved
Investigational
Matched Iupac: … (1S,2R,18R,19R,22S,25R,28R,40S)-2-{[(2R,4S,5R,6S)-4-amino-5-hydroxy-4,6-dimethyloxan-2-yl]oxy}-22-(carbamoylmethyl ... )-5,47-dichloro-48-{[(2S,3R,4S,5S,6R)-3-{[(2S,4S,5R,6S)-4-[({4'-chloro-[1,1'-biphenyl]-4-yl}methyl)amino ... ]-5-hydroxy-4,6-dimethyloxan-2-yl]oxy}-4,5-dihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy}-18,32,35,37-tetrahydroxy ... [26.14.2.2^{3,6}.2^{14,17}.1^{8,12}.1^{29,33}.0^{10,25}.0^{34,39}]pentaconta-3,5,8,10,12(48),14,16,29 ... -19-[(2R)-4-methyl-2-(methylamino)pentanamido]-20,23,26,42,44-pentaoxo-7,13-dioxa-21,24,27,41,43-pentaazaoctacyclo …
Matched Description: … [L32634] Orbactiv, the other FDA approved oritavancin product, is administered over a 3 hour infusion ... Oritavancin is a glycopeptide antibiotic used for the treatment of skin infections. ... [A39384,A193482,L8492] On March 12, 2021 the FDA approved Kimyrsa, a complete course of therapy in …
Matched Categories: … Antibacterials for Systemic Use ... Antiinfectives for Systemic Use …
Matched Description: … [L32634] Orbactiv, the other FDA approved oritavancin product, is administered over a 3 hour infusion ... Oritavancin is a glycopeptide antibiotic used for the treatment of skin infections. ... [A39384,A193482,L8492] On March 12, 2021 the FDA approved Kimyrsa, a complete course of therapy in …
Matched Categories: … Antibacterials for Systemic Use ... Antiinfectives for Systemic Use …
Isometheptene
Isometheptene is a sympathomimetic drug that causes vasoconstriction. It is used for treating migraines and tension headaches.
Approved
Matched Iupac: … methyl(6-methylhept-5-en-2-yl)amine …
Matched Description: … It is used for treating migraines and tension headaches. ... Isometheptene is a sympathomimetic drug that causes vasoconstriction. …
Matched Categories: … Drugs for Functional Gastrointestinal Disorders …
Matched Description: … It is used for treating migraines and tension headaches. ... Isometheptene is a sympathomimetic drug that causes vasoconstriction. …
Matched Categories: … Drugs for Functional Gastrointestinal Disorders …
Pascopyrum smithii pollen
Pascopyrum smithii pollen is the pollen of the Pascopyrum smithii plant. Pascopyrum smithii pollen is mainly used in allergenic testing.
Approved
Matched Description: … Pascopyrum smithii pollen is mainly used in allergenic testing. …
Levomenol
Bisabolol, or more formally α-(−)-bisabolol or also known as levomenol, (-)-alpha-Bisabolol is found in fats and oils. (-)-alpha-Bisabolol is isolated from essential oil of Matricaria chamomilla (German chamomile) (-)-alpha-Bisabolol belongs to the family of Sesquiterpenes. These are terpenes with three consecutive isoprene units.
Approved
Experimental
Matched Iupac: … (2S)-6-methyl-2-[(1S)-4-methylcyclohex-3-en-1-yl]hept-5-en-2-ol …
Matched Description: … Bisabolol, or more formally α-(−)-bisabolol or also known as levomenol, (-)-alpha-Bisabolol is found in …
Matched Mixtures name: … Intense Multi Ampoule Balm Vita C ... NEWSTEM Rx IPL VITA C Energy Ampoule …
Matched Description: … Bisabolol, or more formally α-(−)-bisabolol or also known as levomenol, (-)-alpha-Bisabolol is found in …
Matched Mixtures name: … Intense Multi Ampoule Balm Vita C ... NEWSTEM Rx IPL VITA C Energy Ampoule …
Telithromycin
Telithromycin, a semi-synthetic erythromycin derivative, belongs to a new chemical class of antibiotics called ketolides. Ketolides have been recently added to the macrolide-lincosamide-streptogramin class of antibiotics. Similar to the macrolide antibiotics, telithromycin prevents bacterial growth by interfering with bacterial protein synthesis. Telithromycin binds to the 50S subunit of the 70S...
Approved
Matched Iupac: … (3aS,4R,7R,9R,10R,11R,13R,15R,15aR)-10-{[(2S,3R,4S,6R)-4-(dimethylamino)-3-hydroxy-6-methyloxan-2-yl] ... oxy}-4-ethyl-11-methoxy-3a,7,9,11,13,15-hexamethyl-1-{4-[4-(pyridin-3-yl)-1H-imidazol-1-yl]butyl}-tetradecahydro …
Matched Description: … Telithromycin, a semi-synthetic erythromycin derivative, belongs to a new chemical class of antibiotics …
Matched Categories: … Antibacterials for Systemic Use ... Antiinfectives for Systemic Use …
Matched Description: … Telithromycin, a semi-synthetic erythromycin derivative, belongs to a new chemical class of antibiotics …
Matched Categories: … Antibacterials for Systemic Use ... Antiinfectives for Systemic Use …
Displaying drugs 1151 - 1175 of 15670 in total