Displaying drugs 15476 - 15500 of 15549 in total
Larotaxel
Larotaxel has been used in trials studying the treatment of Cancer, Metastases, Breast Cancer, Breast Neoplasms, and Pancreatic Neoplasms, among others.
Investigational
Matched Iupac: … (1S,2S,3R,4S,7R,9S,11R,13R,16S)-4,13-bis(acetyloxy)-16-{[(2R,3S)-3-{[(tert-butoxy)carbonyl]amino}-2-hydroxy ... ^{9,11}]octadec-14-en-2-yl benzoate ... -3-phenylpropanoyl]oxy}-1-hydroxy-15,18,18-trimethyl-12-oxo-6-oxapentacyclo[12.3.1.0^{3,11}.0^{4,7}.0 …
Matched Description: … Larotaxel has been used in trials studying the treatment of Cancer, Metastases, Breast Cancer, Breast …
Matched Description: … Larotaxel has been used in trials studying the treatment of Cancer, Metastases, Breast Cancer, Breast …
RCT1100
RCT1100 is an investigational mRNA-based therapeutic that aims to treat primary ciliary dyskinesia caused by pathogenic mutations in DNAI1.
Investigational
Matched Description: … mRNA-based therapeutic that aims to treat primary ciliary dyskinesia caused by pathogenic mutations in …
Guanosine-5'-Monophosphate
Guanosine 5'-monophosphate. A guanine nucleotide containing one phosphate group esterified to the sugar moiety and found widely in nature. [PubChem]
Experimental
Matched Iupac: … {[(2R,3S,4R,5R)-5-(2-amino-6-oxo-6,9-dihydro-1H-purin-9-yl)-3,4-dihydroxyoxolan-2-yl]methoxy}phosphonic …
Matched Description: … A guanine nucleotide containing one phosphate group esterified to the sugar moiety and found widely in …
Matched Description: … A guanine nucleotide containing one phosphate group esterified to the sugar moiety and found widely in …
HT-0712
BLX-028914 has been used in trials studying the treatment and basic science of Allergic Rhinitis and Age-Associated Memory Impairment (AAMI).
Investigational
Matched Iupac: … (3S,5S)-5-[3-(cyclopentyloxy)-4-methoxyphenyl]-3-[(3-methylphenyl)methyl]piperidin-2-one …
Matched Description: … BLX-028914 has been used in trials studying the treatment and basic science of Allergic Rhinitis and …
Matched Description: … BLX-028914 has been used in trials studying the treatment and basic science of Allergic Rhinitis and …
PF-00489791
PF-00489791 has been used in trials studying the treatment of Hypertension, Raynaud's Disease, Diabetic Nephropathies, Hypertension, Pulmonary, and Peripheral Vascular Disease.
Investigational
Matched Iupac: … [4,3-d]pyrimidine-3-carboxamide ... 1-(2-ethoxyethyl)-5-[ethyl(methyl)amino]-N-methanesulfonyl-7-[(4-methylpyridin-2-yl)amino]-1H-pyrazolo …
Matched Description: … PF-00489791 has been used in trials studying the treatment of Hypertension, Raynaud's Disease, Diabetic …
Matched Description: … PF-00489791 has been used in trials studying the treatment of Hypertension, Raynaud's Disease, Diabetic …
Pevonedistat
Pevonedistat has been used in trials studying the treatment of Lymphoma, Solid Tumors, Multiple Myeloma, Hodgkin Lymphoma, and Metastatic Melanoma, among others.
Investigational
Matched Iupac: … [(1S,2S,4R)-4-(4-{[(1S)-2,3-dihydro-1H-inden-1-yl]amino}-7H-pyrrolo[2,3-d]pyrimidin-7-yl)-2-hydroxycyclopentyl …
Matched Description: … Pevonedistat has been used in trials studying the treatment of Lymphoma, Solid Tumors, Multiple Myeloma …
Matched Description: … Pevonedistat has been used in trials studying the treatment of Lymphoma, Solid Tumors, Multiple Myeloma …
Verinurad
Verinurad has been used in trials studying the basic science and treatment of Gout, Gout and Hyperuricemia, and Gout and Asymptomatic Hyperuricemia.
Investigational
Matched Iupac: … 2-{[3-(4-cyanonaphthalen-1-yl)pyridin-4-yl]sulfanyl}-2-methylpropanoic acid …
Matched Description: … Verinurad has been used in trials studying the basic science and treatment of Gout, Gout and Hyperuricemia …
Matched Description: … Verinurad has been used in trials studying the basic science and treatment of Gout, Gout and Hyperuricemia …
Lesogaberan
Lesogaberan has been used in trials studying the treatment and basic science of GERD, Reflux, Heartburn, Regurgitation, and Reflux Disease, among others.
Investigational
Matched Iupac: … [(2R)-3-amino-2-fluoropropyl]phosphinic acid …
Matched Description: … Lesogaberan has been used in trials studying the treatment and basic science of GERD, Reflux, Heartburn …
Matched Categories: … GABA-A Receptor Agonists …
Matched Description: … Lesogaberan has been used in trials studying the treatment and basic science of GERD, Reflux, Heartburn …
Matched Categories: … GABA-A Receptor Agonists …
GSK-1059615
GSK1059615 has been used in trials studying the treatment of Lymphoma, Solid Tumours, Endometrial Cancer, Solid Tumor Cancer, and Metastatic Breast Cancer.
Investigational
Matched Description: … GSK1059615 has been used in trials studying the treatment of Lymphoma, Solid Tumours, Endometrial Cancer …
JNJ-40411813
JNJ-40411813 has been used in trials studying the treatment and basic science of Confusion, Schizophrenia, Perceptual Disorders, and Major Depressive Disorder.
Investigational
Matched Iupac: … 1-butyl-3-chloro-4-(4-phenylpiperidin-1-yl)-1,2-dihydropyridin-2-one …
Matched Description: … JNJ-40411813 has been used in trials studying the treatment and basic science of Confusion, Schizophrenia …
Matched Description: … JNJ-40411813 has been used in trials studying the treatment and basic science of Confusion, Schizophrenia …
PF-03715455
PF-03715455 has been used in trials studying the treatment of Asthma, Pulmonary Disease, Chronic Obstructive, and Chronic Obstructive Pulmonary Disease (COPD).
Investigational
Matched Iupac: … 3-[3-tert-butyl-1-(3-chloro-4-hydroxyphenyl)-1H-pyrazol-5-yl]-1-({2-[(3-{2-[(2-hydroxyethyl)sulfanyl] ... phenyl}-[1,2,4]triazolo[4,3-a]pyridin-6-yl)sulfanyl]phenyl}methyl)urea …
Matched Description: … PF-03715455 has been used in trials studying the treatment of Asthma, Pulmonary Disease, Chronic Obstructive …
Matched Categories: … Heterocyclic Compounds, 2-Ring …
Matched Description: … PF-03715455 has been used in trials studying the treatment of Asthma, Pulmonary Disease, Chronic Obstructive …
Matched Categories: … Heterocyclic Compounds, 2-Ring …
Tradipitant
Tradipitant has been used in trials studying the treatment and prevention of Eczema, Pruritus, Gastroparesis, Chronic Pruritus, and Atopic Dermatitis, among others.
Investigational
Matched Iupac: … 2-(1-{[3,5-bis(trifluoromethyl)phenyl]methyl}-5-(pyridin-4-yl)-1H-1,2,3-triazol-4-yl)-3-(2-chlorobenzoyl …
Matched Description: … Tradipitant has been used in trials studying the treatment and prevention of Eczema, Pruritus, Gastroparesis …
Matched Description: … Tradipitant has been used in trials studying the treatment and prevention of Eczema, Pruritus, Gastroparesis …
Pyroxamide
Pyroxamide has been used in trials studying the treatment of Leukemia, Lymphoma, Small Intestine Cancer, Precancerous Condition, and Myelodysplastic Syndromes, among others.
Investigational
Matched Iupac: … N-hydroxy-N'-(pyridin-3-yl)octanediamide …
Matched Description: … Pyroxamide has been used in trials studying the treatment of Leukemia, Lymphoma, Small Intestine Cancer …
Matched Description: … Pyroxamide has been used in trials studying the treatment of Leukemia, Lymphoma, Small Intestine Cancer …
Tripterygium wilfordii whole
Tripterygium wilfordii whole is a plant/plant extract used in some OTC (over-the-counter) products. It is not an approved drug.
Experimental
Matched Description: … Tripterygium wilfordii whole is a plant/plant extract used in some OTC (over-the-counter) products. …
Naquotinib
Naquotinib has been used in trials studying the treatment of Solid Tumors, Non-small Cell Lung Cancer, Non-Small-Cell Lung Cancer (NSCLC), Epidermal Growth Factor Receptor Mutations, and Epidermal Growth Factor Receptor (EGFR) Mutations, among others.
Investigational
Matched Iupac: … -3-yl]oxy}pyrazine-2-carboxamide ... 6-ethyl-3-({4-[4-(4-methylpiperazin-1-yl)piperidin-1-yl]phenyl}amino)-5-{[(3R)-1-(prop-2-enoyl)pyrrolidin …
Matched Description: … Naquotinib has been used in trials studying the treatment of Solid Tumors, Non-small Cell Lung Cancer …
Matched Description: … Naquotinib has been used in trials studying the treatment of Solid Tumors, Non-small Cell Lung Cancer …
Lirilumab
Lirilumab has been used in trials studying the treatment of Leukemia, CANCER,NOS, Multiple Myeloma, Lymphocytic Leukemia, and Acute Myeloid Leukemia, among others.
Investigational
Matched Description: … Lirilumab has been used in trials studying the treatment of Leukemia, CANCER,NOS, Multiple Myeloma, Lymphocytic …
Preladenant
Preladenant has been used in trials studying the treatment of Brain Diseases, Parkinson Disease, Movement Disorders, Antipsychotic Agents, and Parkinsonian Disorders, among others.
Investigational
Matched Iupac: … 4-(furan-2-yl)-10-(2-{4-[4-(2-methoxyethoxy)phenyl]piperazin-1-yl}ethyl)-3,5,6,8,10,11-hexaazatricyclo …
Matched Description: … Preladenant has been used in trials studying the treatment of Brain Diseases, Parkinson Disease, Movement …
Matched Description: … Preladenant has been used in trials studying the treatment of Brain Diseases, Parkinson Disease, Movement …
Vadastuximab talirine
Vadastuximab Talirine has been used in trials studying the treatment of Acute myeloid leukemia, Myelodysplastic Syndrome, Acute Myelogenous Leukemia, and Acute Promyelocytic Leukemia.
Investigational
Matched Description: … Vadastuximab Talirine has been used in trials studying the treatment of Acute myeloid leukemia, Myelodysplastic …
Matched Categories: … Heterocyclic Compounds, 2-Ring …
Matched Categories: … Heterocyclic Compounds, 2-Ring …
Galunisertib
Galunisertib has been used in trials studying the basic science and treatment of Glioma, Neoplasms, Solid Tumor, GLIOBLASTOMA, and Prostate Cancer, among others.
Investigational
Matched Iupac: … 4-[2-(6-methylpyridin-2-yl)-4H,5H,6H-pyrrolo[1,2-b]pyrazol-3-yl]quinoline-6-carboxamide …
Matched Description: … Galunisertib has been used in trials studying the basic science and treatment of Glioma, Neoplasms, Solid …
Matched Categories: … Heterocyclic Compounds, 2-Ring …
Matched Description: … Galunisertib has been used in trials studying the basic science and treatment of Glioma, Neoplasms, Solid …
Matched Categories: … Heterocyclic Compounds, 2-Ring …
Lorvotuzumab mertansine
Lorvotuzumab mertansine has been used in trials studying the treatment of SCLC, Leukemia, Ovarian Cancer, Multiple Myeloma, and Merkel Cell Carcinoma, among others.
Investigational
Matched Description: … Lorvotuzumab mertansine has been used in trials studying the treatment of SCLC, Leukemia, Ovarian Cancer …
Ganitumab
Ganitumab has been used in trials studying the treatment of Colon Cancer, Rectal Cancer, Breast Cancer, Breast Tumors, and Breast Neoplasms, among others.
Investigational
Matched Description: … Ganitumab has been used in trials studying the treatment of Colon Cancer, Rectal Cancer, Breast Cancer …
Sofinicline
Sofinicline has been used in trials studying the treatment of ADHD, Neuralgia, Diabetic, Diabetic Neuropathies, Diabetic Polyneuropathy, and Diabetic Neuropathic Pain, among others.
Investigational
Matched Iupac: … (1S,5S)-3-(5,6-dichloropyridin-3-yl)-3,6-diazabicyclo[3.2.0]heptane …
Matched Description: … Sofinicline has been used in trials studying the treatment of ADHD, Neuralgia, Diabetic, Diabetic Neuropathies …
Matched Description: … Sofinicline has been used in trials studying the treatment of ADHD, Neuralgia, Diabetic, Diabetic Neuropathies …
VM4-037
VM4-037 is under investigation in clinical trial NCT00884520 (An Exploratory, Open Label, Multi-Center, Non-Randomized Study of [F-18]VM4-037).
Investigational
Matched Iupac: … (2S)-3-[4-(2-fluoroethoxy)phenyl]-2-[(2S)-3-methyl-2-(4-{[(2-sulfamoyl-1,3-benzothiazol-6-yl)oxy]methyl …
Matched Description: … , Non-Randomized Study of [F-18]VM4-037). ... VM4-037 is under investigation in clinical trial NCT00884520 (An Exploratory, Open Label, Multi-Center …
Matched Description: … , Non-Randomized Study of [F-18]VM4-037). ... VM4-037 is under investigation in clinical trial NCT00884520 (An Exploratory, Open Label, Multi-Center …
MK-1454
A synthetic cyclic dinucleotide (CDN) and agonist of stimulator of interferon genes protein (STING), with potential immunoactivating and antineoplastic activities. Upon intratumoral (IT) administration, STING agonist MK-1454 binds to STING and activates the STING pathway, which promotes IKK-related kinase TANK-binding kinase 1 (TBK1) signaling and activates nuclear factor-kappa B (NF-kB)...
Investigational
Matched Description: … This results in a CTL-mediated immune response against tumor cells and causes tumor cell lysis. ... kinase 1 (TBK1) signaling and activates nuclear factor-kappa B (NF-kB) and interferon regulatory factor 3 ... (IRF3) in immune cells in the tumor microenvironment; this leads to the production of pro-inflammatory …
ZYCOV-D
The ZYCOV-D vaccine candidate was developed by Cadila Healthcare Ltd. based in India . The vaccine was developed using a DNA vaccine platform with a non-replicating and non-integrating plasmid carrying the gene of interest . Once the plasmid DNA is introduced into host cells and the viral protein is translated,...
Investigational
Matched Description: … The vaccine was developed using a DNA vaccine platform with a non-replicating and non-integrating plasmid ... As of August, 2020 the candidate is in Phase II clinical trials[A219758]. ... The ZYCOV-D vaccine candidate was developed by Cadila Healthcare Ltd. based in India[A219758]. …
Displaying drugs 15476 - 15500 of 15549 in total