Displaying drugs 2876 - 2900 of 3242 in total
Diphenoxylate
A meperidine congener used as an antidiarrheal, usually in combination with atropine. At high doses, it acts like morphine. Its unesterified metabolite difenoxin has similar properties and is used similarly. It has little or no analgesic activity. This medication is classified as a Schedule V under the Controlled Substances Act...
Approved
Illicit
Matched Synonyms: … 1-(3-Cyano-3,3-diphenylpropyl)-4-phenyl-isonipecotic acid ethyl ester …
Matched Description: … Its unesterified metabolite difenoxin has similar properties and is used similarly. ... Administration (FDA) and the DEA in the United States when used in preparations. ... This medication is classified as a Schedule V under the Controlled Substances Act by the Food and Drug …
Matched Mixtures name: … Diphenoxylate Hydrochloride and Atropine Sulfate ... Diphenoxylate Hydrochloride and Atropine Sulfate ... Diphenoxylate Hydrochloride and Atropine Sulfate …
Matched Categories: … Alimentary Tract and Metabolism ... Acids, Heterocyclic ... Isonipecotic Acids …
Matched Description: … Its unesterified metabolite difenoxin has similar properties and is used similarly. ... Administration (FDA) and the DEA in the United States when used in preparations. ... This medication is classified as a Schedule V under the Controlled Substances Act by the Food and Drug …
Matched Mixtures name: … Diphenoxylate Hydrochloride and Atropine Sulfate ... Diphenoxylate Hydrochloride and Atropine Sulfate ... Diphenoxylate Hydrochloride and Atropine Sulfate …
Matched Categories: … Alimentary Tract and Metabolism ... Acids, Heterocyclic ... Isonipecotic Acids …
Esketamine
Major depressive disorder (MDD) is a significant cause of disability worldwide and the most common illness preceding suicide.[L5596,A175462] On March 5, 2019, the nasal spray drug, esketamine, also known as Spravato (by Janssen Pharmaceuticals), was approved by the FDA for treatment-resistant major depression.
Esketamine is the s-enantiomer of Ketamine. Ketamine...
Approved
Investigational
Matched Synonyms: … L-ketamine …
Matched Description: … Major depressive disorder (MDD) is a significant cause of disability worldwide and the most common illness ... The intranasal route of administration for this drug allows for easy administration and a fast onset ... disorder who have not experienced an improvement in symptoms despite treatment with various medications and …
Matched Description: … Major depressive disorder (MDD) is a significant cause of disability worldwide and the most common illness ... The intranasal route of administration for this drug allows for easy administration and a fast onset ... disorder who have not experienced an improvement in symptoms despite treatment with various medications and …
L-Alpha-Phosphatidyl-Beta-Oleoyl-Gamma-Palmitoyl-Phosphatidylethanolamine
Experimental
Matched Name: … L-Alpha-Phosphatidyl-Beta-Oleoyl-Gamma-Palmitoyl-Phosphatidylethanolamine …
Matched Iupac: … )-2-[(9E,12E)-hexadeca-9,12-dienoyloxy]-3-[(8E,16E)-octadeca-8,12,16-trienoyloxy]propoxy]phosphinic acid …
Matched Iupac: … )-2-[(9E,12E)-hexadeca-9,12-dienoyloxy]-3-[(8E,16E)-octadeca-8,12,16-trienoyloxy]propoxy]phosphinic acid …
S-[3-(3,4-DICHLOROPHENYL)-3-OXOPROPYL]-L-CYSTEINE
Experimental
Matched Name: … S-[3-(3,4-DICHLOROPHENYL)-3-OXOPROPYL]-L-CYSTEINE …
Matched Iupac: … (2R)-2-amino-3-{[3-(3,4-dichlorophenyl)-3-oxopropyl]sulfanyl}propanoic acid …
Matched Iupac: … (2R)-2-amino-3-{[3-(3,4-dichlorophenyl)-3-oxopropyl]sulfanyl}propanoic acid …
Durlobactam
Durlobactam is a diazabicyclooctane non-beta-lactam, beta-lactamase inhibitor. It is typically given in combination with sulbactam to protect it from degradation by certain serine-beta-lactamases. The combination product of durlobactam and sulbactam was first approved by the FDA in May 2023. It is used to treat hospital-acquired bacterial pneumonia and ventilator-associated bacterial...
Approved
Investigational
Matched Synonyms: … SULFURIC ACID, MONO((2S,5R)-2-(AMINOCARBONYL)-3-METHYL-7-OXO-1,6-DIAZABICYCLO(3.2.1)OCT-3-EN-6-YL) ESTER …
Matched Iupac: … [(1R,2S,5R)-2-carbamoyl-3-methyl-7-oxo-1,6-diazabicyclo[3.2.1]oct-3-en-6-yl]oxidanesulfonic acid …
Matched Description: … [L47336] The combination product of durlobactam and sulbactam was first approved by the FDA in May 2023 ... [A263306] It is used to treat hospital-acquired bacterial pneumonia and ventilator-associated bacterial ... It is typically given in combination with [sulbactam] to protect it from degradation by certain serine-beta-lactamases …
Matched Iupac: … [(1R,2S,5R)-2-carbamoyl-3-methyl-7-oxo-1,6-diazabicyclo[3.2.1]oct-3-en-6-yl]oxidanesulfonic acid …
Matched Description: … [L47336] The combination product of durlobactam and sulbactam was first approved by the FDA in May 2023 ... [A263306] It is used to treat hospital-acquired bacterial pneumonia and ventilator-associated bacterial ... It is typically given in combination with [sulbactam] to protect it from degradation by certain serine-beta-lactamases …
Lipotecan
Investigational
Matched Synonyms: … Propanoic acid, 2-(((2,4,5,7-tetranitro-9h-fluoren-9-ylidene)amino)oxy)-, (4s)-10-((dimethylamino)methyl …
N,N'-[biphenyl-4,4'-diyldi(2R)propane-2,1-diyl]dimethanesulfonamide
Experimental
Matched Name: … N,N'-[biphenyl-4,4'-diyldi(2R)propane-2,1-diyl]dimethanesulfonamide …
Berubicin
Investigational
Matched Synonyms: … (8s,10s)-10-((3-amino-4-o-benzyl-2,3,6-trideoxy-a-l-lyxo-hexopyranosyl)oxy)-6,8,11-trihydroxy-8-(hydroxyacetyl ... -l-lyxo-hexopyranosyl)oxy)-7,8,9,10-tetrahydro-6,8,11-trihydroxy-8-(hydroxyacetyl)-1-methoxy-, (8s,10s …
Human blood group H type 1 trisaccharide
Experimental
Matched Synonyms: … α-L-Fuc-(1→2)-β-D-Gal-(1→3)-β-D-GlcNAc ... alpha-L-Fucp-(1->2)-beta-D-Galp-(1->3)-beta-D-GlcpNAc …
Amikacin
Amikacin is a semi-synthetic aminoglycoside antibiotic that is derived from kanamycin A.[FDA label] Amikacin is synthesized by acylation with the l-(-)-γ-amino-α-hydroxybutyryl side chain at the C-1 amino group of the deoxystreptamine moiety of kanamycin A. Amikacin's unique property is that it exerts activity against more resistant gram-negative bacilli such as...
Approved
Investigational
Vet approved
Matched Synonyms: … -D-GLUCOPYRANOSYL-(1->6))-N(SUP 3)-(4-AMINO-L-2-HYDROXYBUTYRYL)-2-DEOXY-L-STREPTAMINE ... 1-N-(L(−)-γ-amino-α-hydroxybutyryl)kanamycin A …
Matched Description: … of breath and the coughing up of blood. ... that it exerts activity against more resistant gram-negative bacilli such as Acinetobacter baumanii and ... some Mycobacterium (M. avium-intracellulare, M. chelonae, and M. fortuitum)[L4680]. …
Matched Categories: … cefepime and amikacin …
Matched Description: … of breath and the coughing up of blood. ... that it exerts activity against more resistant gram-negative bacilli such as Acinetobacter baumanii and ... some Mycobacterium (M. avium-intracellulare, M. chelonae, and M. fortuitum)[L4680]. …
Matched Categories: … cefepime and amikacin …
CT-179
Investigational
Matched Synonyms: … 1-(2-(3-(3,4-dichlorophenyl)ureido)-6-methyl-pyrimidin-4-yl)-amino-3(dimethylamino)propane …
Remifentanil
Remifentanil (marketed by Abbott as Ultiva) is a potent ultra short-acting synthetic opioid given to patients during surgery for pain relief and adjunctive to an anaesthetic. Remifentanil is a specific mu-type-opioid receptor agonist which means it reduces sympathetic nervous system tone, and causes respiratory depression and analgesia.
Approved
Matched Description: … causes respiratory depression and analgesia. ... Ultiva) is a potent ultra short-acting synthetic opioid given to patients during surgery for pain relief and ... a specific mu-type-opioid receptor agonist which means it reduces sympathetic nervous system tone, and …
Matched Categories: … Fentanyl and fentanyl analogues ... Hypnotics and Sedatives ... Acids, Acyclic ... Carboxylic Acids …
Matched Products: … SERILONE® 2MG POLVO PARA SOLUCIÓN INYECTABLE …
Matched Categories: … Fentanyl and fentanyl analogues ... Hypnotics and Sedatives ... Acids, Acyclic ... Carboxylic Acids …
Matched Products: … SERILONE® 2MG POLVO PARA SOLUCIÓN INYECTABLE …
Ceftaroline fosamil
Ceftaroline fosamil is a cephalosporin antibacterial indicated for the treatment of the following infections caused by designated susceptible bacteria:
Acute bacterial skin and skin structure infections.
Community-acquired bacterial pneumonia.
Approved
Investigational
Matched Synonyms: … (6R,7R)-7-[(2Z)-2-ethoxyimino-2-[5-(phosphonoamino)-1,2,4-thiadiazol-3-yl]acetyl]amino]-3-[4-(1-methylpyridin …
Matched Description: … treatment of the following infections caused by designated susceptible bacteria: Acute bacterial skin and …
Matched Salts name: … Ceftaroline fosamil acetate ... Ceftaroline fosamil acetate monohydrate …
Matched Description: … treatment of the following infections caused by designated susceptible bacteria: Acute bacterial skin and …
Matched Salts name: … Ceftaroline fosamil acetate ... Ceftaroline fosamil acetate monohydrate …
Vocacapsaicin
Investigational
Matched Synonyms: … 1-piperidinecarboxylic acid, 2-((methylamino)methyl)-, 2-methoxy-4-((((6e)-8-methyl-1-oxo-6-nonen-1-yl …
Ceftolozane
Ceftolozane is a semi-synthetic broad-spectrum fifth generation cephalosporin. It was approved by the FDA in 2014 for use in combination with Tazobactam for the treatment of serious infections, such as intra-abdominal infections and complicated urinary tract infections. The manufacturer of this drug is Cubist Pharmaceuticals. Most recently, in June 2019,...
Approved
Investigational
Matched Synonyms: … methylpyrazol-1-ium-1-yl]methyl)-7-([(2Z)-2-(5-amino-1,2,4-thiadiazol-3-yl)-2-(2-carboxypropan-2-yloxyimino)acetyl …
Matched Description: … and mortality in hospitalized patients and the use of ceftolozane-tazobactam offers effective activity ... combination with [Tazobactam] for the treatment of serious infections, such as intra-abdominal infections and ... 2019, ceftolozane-tazobactam was approved for the treatment of hospital-acquired bacterial pneumonia and …
Matched Description: … and mortality in hospitalized patients and the use of ceftolozane-tazobactam offers effective activity ... combination with [Tazobactam] for the treatment of serious infections, such as intra-abdominal infections and ... 2019, ceftolozane-tazobactam was approved for the treatment of hospital-acquired bacterial pneumonia and …
Lirentelimab
Lirentelimab is under investigation in clinical trial NCT04856891 (A Study of Lirentelimab (AK002) in Patients With Active Eosinophilic Duodenitis).
Investigational
Matched Synonyms: … IMMUNOGLOBULIN G1-KAPPA, ANTI-(HOMO SAPIENS SIALIC ACID-BINDING IG-LIKE LECTIN 8 (SIALOADHESIN FAMILY ... IMMUNOGLOBULIN G1, ANTI-(HUMAN SIALIC ACID-BINDINGE IG-LIKE LECTIN 8) (HUMAN-MUS MUSCULUS MONOCLONAL …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Gandotinib
Gandotinib has been used in trials studying the treatment of Myelofibrosis, Polycythemia Vera, Primary Myelofibrosis, Thrombocythemia, Essential, and Myeloproliferative Disorders, among others.
Investigational
Matched Synonyms: … Adenosine triphosphate type 1 competitive inhibitor of JAK2 V617F tyrosine kinase …
Matched Description: … the treatment of Myelofibrosis, Polycythemia Vera, Primary Myelofibrosis, Thrombocythemia, Essential, and …
Matched Description: … the treatment of Myelofibrosis, Polycythemia Vera, Primary Myelofibrosis, Thrombocythemia, Essential, and …
Idursulfase beta
Idursulfase beta is under investigation in clinical trial NCT01645189 (Safety and Efficacy of Hunterase).
Investigational
Matched Synonyms: … Iduronate 2-sulfatase (a-l-iduronate sulfate sulfatase), human proenzyme produced in cho cells (glycoform …
Matched Description: … Idursulfase beta is under investigation in clinical trial NCT01645189 (Safety and Efficacy of Hunterase …
Matched Categories: … Alimentary Tract and Metabolism ... Enzymes and Coenzymes …
Matched Description: … Idursulfase beta is under investigation in clinical trial NCT01645189 (Safety and Efficacy of Hunterase …
Matched Categories: … Alimentary Tract and Metabolism ... Enzymes and Coenzymes …
1-(5-Carboxypentyl)-5-[(2,6-Dichlorobenzyl)Oxy]-1 H-Indole-2-Carboxylic Acid
Experimental
Matched Name: … 1-(5-Carboxypentyl)-5-[(2,6-Dichlorobenzyl)Oxy]-1 H-Indole-2-Carboxylic Acid …
Matched Iupac: … 1-(5-carboxypentyl)-5-[(2,6-dichlorophenyl)methoxy]-1H-indole-2-carboxylic acid …
Matched Iupac: … 1-(5-carboxypentyl)-5-[(2,6-dichlorophenyl)methoxy]-1H-indole-2-carboxylic acid …
1-Methyl-3-Oxo-1,3-Dihydro-Benzo[C]Isothiazole-5-Sulfonic Acid Amide
Experimental
Matched Name: … 1-Methyl-3-Oxo-1,3-Dihydro-Benzo[C]Isothiazole-5-Sulfonic Acid Amide …
4-Carbamoyl-4-{[6-(Difluoro-Phosphono-Methyl)-Naphthalene-2-Carbonyl]-Amino}-Butyric Acid
Experimental
Matched Name: … 4-Carbamoyl-4-{[6-(Difluoro-Phosphono-Methyl)-Naphthalene-2-Carbonyl]-Amino}-Butyric Acid …
Matched Iupac: … (4S)-4-carbamoyl-4-({6-[difluoro(phosphono)methyl]naphthalen-2-yl}formamido)butanoic acid …
Matched Iupac: … (4S)-4-carbamoyl-4-({6-[difluoro(phosphono)methyl]naphthalen-2-yl}formamido)butanoic acid …
Methyl-[4-(4-Piperidine-1-Ylmethyl-Phenyl)-Cyclohexyl]-Carbaminic Acid-(4-Chlorophenyl)-Ester
Experimental
Matched Name: … Methyl-[4-(4-Piperidine-1-Ylmethyl-Phenyl)-Cyclohexyl]-Carbaminic Acid-(4-Chlorophenyl)-Ester …
3-(3,5-Dibromo-4-Hydroxy-Benzoyl)-2-Ethyl-Benzofuran-6-Sulfonic Acid Dimethylamide
Experimental
Matched Name: … 3-(3,5-Dibromo-4-Hydroxy-Benzoyl)-2-Ethyl-Benzofuran-6-Sulfonic Acid Dimethylamide …
(2Z,4E)-3-chloro-2-hydroxy-6-oxo-6-phenylhexa-2,4-dienoic acid
Experimental
Matched Name: … (2Z,4E)-3-chloro-2-hydroxy-6-oxo-6-phenylhexa-2,4-dienoic acid …
Matched Iupac: … (2Z,4E)-3-chloro-2-hydroxy-6-oxo-6-phenylhexa-2,4-dienoic acid …
Matched Iupac: … (2Z,4E)-3-chloro-2-hydroxy-6-oxo-6-phenylhexa-2,4-dienoic acid …
Displaying drugs 2876 - 2900 of 3242 in total