Displaying drugs 2926 - 2950 of 3378 in total
osgemcitabine palabenamide
NUC-1031 is under investigation in clinical trial NCT03610100 (Acelarin First Line Randomised Pancreatic Study).
Investigational
Matched Synonyms: … -cytidylyl]-L-alanine phenylmethyl ester ... L-ALANINE, N-(2'-DEOXY-2',2'-DIFLUORO-P-PHENYL-5'-CYTIDYLYL)-, PHENYLMETHYL ESTER ... L-Alanine, N-[[P(S)]-2?-deoxy-2?,2?-difluoro-P-phenyl-5?-cytidylyl]-, phenylmethyl ester …
Matched Categories: … Nucleic Acids, Nucleotides, and Nucleosides …
Matched Categories: … Nucleic Acids, Nucleotides, and Nucleosides …
Human blood group H type 1 trisaccharide
Experimental
Matched Synonyms: … α-L-Fuc-(1→2)-β-D-Gal-(1→3)-β-D-GlcNAc ... alpha-L-Fucp-(1->2)-beta-D-Galp-(1->3)-beta-D-GlcpNAc …
Efungumab
Efungumab is under investigation in clinical trial NCT00217815 (Preliminary Study of Mycograb and Docetaxel in Advanced Breast Cancer).
Investigational
Matched Synonyms: … Immunoglobulin, anti-(candida heat-shock protein hsp 90) (human monoclonal hsp90mab fragment) …
Matched Description: … Efungumab is under investigation in clinical trial NCT00217815 (Preliminary Study of Mycograb and Docetaxel …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Proteins ... Blood Proteins ... HSP90 Heat-Shock Proteins …
Matched Description: … Efungumab is under investigation in clinical trial NCT00217815 (Preliminary Study of Mycograb and Docetaxel …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Proteins ... Blood Proteins ... HSP90 Heat-Shock Proteins …
Anti-CD5 CAR T-cell therapy
Investigational
Matched Synonyms: … chimeric antigen receptor (CAR) directed against the target protein CD5 …
Timolumab
Timolumab is a recombinant, fully-human, IgG4 immunoglobulin with antigen-binding specificity for human vascular adhesion protein-1 (VAP-1).
Investigational
Matched Synonyms: … recombinant, fully-human, IgG4 immunoglobulin with antigen-binding specificity for human vascular adhesion protein …
Matched Description: … recombinant, fully-human, IgG4 immunoglobulin with antigen-binding specificity for human vascular adhesion protein …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Proteins ... Blood Proteins …
Matched Description: … recombinant, fully-human, IgG4 immunoglobulin with antigen-binding specificity for human vascular adhesion protein …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Proteins ... Blood Proteins …
L-Alpha-Phosphatidyl-Beta-Oleoyl-Gamma-Palmitoyl-Phosphatidylethanolamine
Experimental
Matched Name: … L-Alpha-Phosphatidyl-Beta-Oleoyl-Gamma-Palmitoyl-Phosphatidylethanolamine …
Matched Iupac: … )-2-[(9E,12E)-hexadeca-9,12-dienoyloxy]-3-[(8E,16E)-octadeca-8,12,16-trienoyloxy]propoxy]phosphinic acid …
Matched Iupac: … )-2-[(9E,12E)-hexadeca-9,12-dienoyloxy]-3-[(8E,16E)-octadeca-8,12,16-trienoyloxy]propoxy]phosphinic acid …
S-[3-(3,4-DICHLOROPHENYL)-3-OXOPROPYL]-L-CYSTEINE
Experimental
Matched Name: … S-[3-(3,4-DICHLOROPHENYL)-3-OXOPROPYL]-L-CYSTEINE …
Matched Iupac: … (2R)-2-amino-3-{[3-(3,4-dichlorophenyl)-3-oxopropyl]sulfanyl}propanoic acid …
Matched Iupac: … (2R)-2-amino-3-{[3-(3,4-dichlorophenyl)-3-oxopropyl]sulfanyl}propanoic acid …
Diphenoxylate
A meperidine congener used as an antidiarrheal, usually in combination with atropine. At high doses, it acts like morphine. Its unesterified metabolite difenoxin has similar properties and is used similarly. It has little or no analgesic activity. This medication is classified as a Schedule V under the Controlled Substances Act...
Approved
Illicit
Matched Synonyms: … 1-(3-Cyano-3,3-diphenylpropyl)-4-phenyl-isonipecotic acid ethyl ester …
Matched Description: … Its unesterified metabolite difenoxin has similar properties and is used similarly. ... At high doses, it acts like morphine. ... Administration (FDA) and the DEA in the United States when used in preparations. …
Matched Mixtures name: … SP-ARNOX SYRUP ... Diphenoxylate Hydrochloride and Atropine Sulfate ... Diphenoxylate Hydrochloride and Atropine Sulfate …
Matched Categories: … Alimentary Tract and Metabolism ... Acids, Heterocyclic ... Isonipecotic Acids …
Matched Description: … Its unesterified metabolite difenoxin has similar properties and is used similarly. ... At high doses, it acts like morphine. ... Administration (FDA) and the DEA in the United States when used in preparations. …
Matched Mixtures name: … SP-ARNOX SYRUP ... Diphenoxylate Hydrochloride and Atropine Sulfate ... Diphenoxylate Hydrochloride and Atropine Sulfate …
Matched Categories: … Alimentary Tract and Metabolism ... Acids, Heterocyclic ... Isonipecotic Acids …
Durlobactam
Durlobactam is a diazabicyclooctane non-beta-lactam, beta-lactamase inhibitor. It is typically given in combination with sulbactam to protect it from degradation by certain serine-beta-lactamases. The combination product of durlobactam and sulbactam was first approved by the FDA in May 2023. It is used to treat hospital-acquired bacterial pneumonia and ventilator-associated bacterial...
Approved
Investigational
Matched Synonyms: … SULFURIC ACID, MONO((2S,5R)-2-(AMINOCARBONYL)-3-METHYL-7-OXO-1,6-DIAZABICYCLO(3.2.1)OCT-3-EN-6-YL) ESTER …
Matched Iupac: … [(1R,2S,5R)-2-carbamoyl-3-methyl-7-oxo-1,6-diazabicyclo[3.2.1]oct-3-en-6-yl]oxidanesulfonic acid …
Matched Description: … [L47336] The combination product of durlobactam and sulbactam was first approved by the FDA in May 2023 ... [A263306] It is used to treat hospital-acquired bacterial pneumonia and ventilator-associated bacterial ... Durlobactam is a diazabicyclooctane non-beta-lactam, beta-lactamase inhibitor. …
Matched Iupac: … [(1R,2S,5R)-2-carbamoyl-3-methyl-7-oxo-1,6-diazabicyclo[3.2.1]oct-3-en-6-yl]oxidanesulfonic acid …
Matched Description: … [L47336] The combination product of durlobactam and sulbactam was first approved by the FDA in May 2023 ... [A263306] It is used to treat hospital-acquired bacterial pneumonia and ventilator-associated bacterial ... Durlobactam is a diazabicyclooctane non-beta-lactam, beta-lactamase inhibitor. …
Lipotecan
Investigational
Matched Synonyms: … Propanoic acid, 2-(((2,4,5,7-tetranitro-9h-fluoren-9-ylidene)amino)oxy)-, (4s)-10-((dimethylamino)methyl …
Liraglutide
Victoza contains liraglutide, a synthetic analog of human glucagon-like peptide-1(GLP-1) and acts as a GLP-1 receptor agonist.[Label,A6932] Liraglutide is 97% similar to native human GLP-1, differing primarily by substituting arginine for lysine at position 34. Liraglutide is made by attaching a C-16 fatty acid (palmitic acid) with a glutamic acid...
Approved
Matched Synonyms: … N²⁶-(N-Hexadecanoyl-L-gamma-glutamyl)-[34-L-arginine]glucagon-like peptide 1-(7-37)-peptide …
Matched Description: … Victoza contains liraglutide, a synthetic analog of human glucagon-like peptide-1(GLP-1) and acts as ... [A6932] Liraglutide is made by attaching a C-16 fatty acid (palmitic acid) with a glutamic acid spacer …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Alimentary Tract and Metabolism ... insulin degludec and liraglutide ... Hormones, Hormone Substitutes, and Hormone Antagonists ... Proteins …
Matched Description: … Victoza contains liraglutide, a synthetic analog of human glucagon-like peptide-1(GLP-1) and acts as ... [A6932] Liraglutide is made by attaching a C-16 fatty acid (palmitic acid) with a glutamic acid spacer …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Alimentary Tract and Metabolism ... insulin degludec and liraglutide ... Hormones, Hormone Substitutes, and Hormone Antagonists ... Proteins …
Berubicin
Investigational
Matched Synonyms: … (8s,10s)-10-((3-amino-4-o-benzyl-2,3,6-trideoxy-a-l-lyxo-hexopyranosyl)oxy)-6,8,11-trihydroxy-8-(hydroxyacetyl ... -l-lyxo-hexopyranosyl)oxy)-7,8,9,10-tetrahydro-6,8,11-trihydroxy-8-(hydroxyacetyl)-1-methoxy-, (8s,10s …
Vocacapsaicin
Investigational
Matched Synonyms: … 1-piperidinecarboxylic acid, 2-((methylamino)methyl)-, 2-methoxy-4-((((6e)-8-methyl-1-oxo-6-nonen-1-yl …
Idursulfase beta
Idursulfase beta is under investigation in clinical trial NCT01645189 (Safety and Efficacy of Hunterase).
Investigational
Matched Synonyms: … Iduronate 2-sulfatase (a-l-iduronate sulfate sulfatase), human proenzyme produced in cho cells (glycoform …
Matched Description: … Idursulfase beta is under investigation in clinical trial NCT01645189 (Safety and Efficacy of Hunterase …
Matched Categories: … Alimentary Tract and Metabolism ... Enzymes and Coenzymes …
Matched Description: … Idursulfase beta is under investigation in clinical trial NCT01645189 (Safety and Efficacy of Hunterase …
Matched Categories: … Alimentary Tract and Metabolism ... Enzymes and Coenzymes …
COVID-19 Nucleocapsid-GM-CSF Protein Lactated Ringer's Injection
As of July 2020, Medicine Invention Design, Inc. is sponsoring a small, controlled clinical trial for the COVID-19 AP TP Vaccine for ‘proof of concept.’ The vaccine utilizes granulocyte macrophage-colony stimulating factor (GM-CSF), a cytokine known to enhance vaccine efficacy through prolongation of humoral and cell immunity.
Investigational
Matched Synonyms: … COVID-19 Therapeutic Vaccine - Nucleocapsid-GM-CSF Protein Lactated Ringer's Injection …
Matched Name: … COVID-19 Nucleocapsid-GM-CSF Protein Lactated Ringer's Injection …
Matched Description: … stimulating factor (GM-CSF), a cytokine known to enhance vaccine efficacy through prolongation of humoral and …
Matched Name: … COVID-19 Nucleocapsid-GM-CSF Protein Lactated Ringer's Injection …
Matched Description: … stimulating factor (GM-CSF), a cytokine known to enhance vaccine efficacy through prolongation of humoral and …
Dornase alfa
Dornase alfa is a biosynthetic form of human deoxyribunuclease I (DNase I) enzyme. It is produced in genetically modified Chinese hamster ovary (CHO) cells using recombinant DNA technology. The 260-amino acid sequence of dornase alfa is identical to the endogenous human enzyme. Dornase alfa cleaves extracellular DNA to 5´-phosphodinucleotide and...
Approved
Matched Synonyms: … Deoxyribonuclease (human clone 18-1 protein moiety) …
Matched Description: … Dornase alfa cleaves extracellular DNA to 5´-phosphodinucleotide and 5´-phosphooligonucleotide end products ... Enzymatic breakdown of this extracellular DNA appears to reduce sputum viscosity and viscoelasticity. ... The 260-amino acid sequence of dornase alfa is identical to the endogenous human enzyme. …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Cough and Cold Preparations ... Enzymes and Coenzymes ... Proteins …
Matched Description: … Dornase alfa cleaves extracellular DNA to 5´-phosphodinucleotide and 5´-phosphooligonucleotide end products ... Enzymatic breakdown of this extracellular DNA appears to reduce sputum viscosity and viscoelasticity. ... The 260-amino acid sequence of dornase alfa is identical to the endogenous human enzyme. …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Cough and Cold Preparations ... Enzymes and Coenzymes ... Proteins …
Amikacin
Amikacin is a semi-synthetic aminoglycoside antibiotic that is derived from kanamycin A.[FDA label] Amikacin is synthesized by acylation with the l-(-)-γ-amino-α-hydroxybutyryl side chain at the C-1 amino group of the deoxystreptamine moiety of kanamycin A. Amikacin's unique property is that it exerts activity against more resistant gram-negative bacilli such as...
Approved
Investigational
Vet approved
Matched Synonyms: … -D-GLUCOPYRANOSYL-(1->6))-N(SUP 3)-(4-AMINO-L-2-HYDROXYBUTYRYL)-2-DEOXY-L-STREPTAMINE ... 1-N-(L(−)-γ-amino-α-hydroxybutyryl)kanamycin A …
Matched Description: … of breath and the coughing up of blood. ... that it exerts activity against more resistant gram-negative bacilli such as Acinetobacter baumanii and ... some Mycobacterium (M. avium-intracellulare, M. chelonae, and M. fortuitum)[L4680]. …
Matched Categories: … cefepime and amikacin …
Matched Description: … of breath and the coughing up of blood. ... that it exerts activity against more resistant gram-negative bacilli such as Acinetobacter baumanii and ... some Mycobacterium (M. avium-intracellulare, M. chelonae, and M. fortuitum)[L4680]. …
Matched Categories: … cefepime and amikacin …
CAN-106
CAN-106 a novel, long-acting monoclonal antibody directed against human complement C5.
Investigational
Matched Synonyms: … Immunoglobulin G [27-histidine,57-histidine,253-tyrosine,255- threonine,257-glutamic acid], anti-(human …
Saruplase
Experimental
Matched Synonyms: … PLASMINOGEN ACTIVATOR, PRO- (HUMAN LIVER UROKINASE-TYPE PROTEIN MOIETY REDUCED) ... KINASE (ENZYME-ACTIVATING), PROURO- (HUMAN CLONE PUK4/PUK18 PROTEIN MOIETY REDUCED) …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Blood and Blood Forming Organs ... Enzymes and Coenzymes ... Proteins ... Blood Proteins …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Blood and Blood Forming Organs ... Enzymes and Coenzymes ... Proteins ... Blood Proteins …
Endostar
Endostar is under investigation for the treatment of Nasopharyngeal Carcinoma. Endostar has been investigated for the treatment of Non-small Cell Lung Cancer.
Investigational
Matched Synonyms: … Recombinant human endostatin protein …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Intercellular Signaling Peptides and Proteins ... Proteins ... Angiogenic Proteins ... Angiostatic Proteins …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Intercellular Signaling Peptides and Proteins ... Proteins ... Angiogenic Proteins ... Angiostatic Proteins …
OMS906
OMS906 is a humanized Igg4 monoclonal antibody against mannan-binding lectin-associated serine protease-3 (MASP-3) currently being developed by Omeros.
Investigational
Matched Synonyms: … Humanized immunoglobulin G4 monoclonal antibody directed against mannan-binding lectin-associated serine protease …
Matched Description: … OMS906 is a humanized Igg4 monoclonal antibody against mannan-binding lectin-associated serine protease …
Matched Description: … OMS906 is a humanized Igg4 monoclonal antibody against mannan-binding lectin-associated serine protease …
Lirentelimab
Lirentelimab is under investigation in clinical trial NCT04856891 (A Study of Lirentelimab (AK002) in Patients With Active Eosinophilic Duodenitis).
Investigational
Matched Synonyms: … IMMUNOGLOBULIN G1-KAPPA, ANTI-(HOMO SAPIENS SIALIC ACID-BINDING IG-LIKE LECTIN 8 (SIALOADHESIN FAMILY ... IMMUNOGLOBULIN G1, ANTI-(HUMAN SIALIC ACID-BINDINGE IG-LIKE LECTIN 8) (HUMAN-MUS MUSCULUS MONOCLONAL …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Proteins ... Blood Proteins …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Proteins ... Blood Proteins …
Diclofenamide
A carbonic anhydrase inhibitor that is used in the treatment of glaucoma.
Approved
Investigational
Matched Synonyms: … 4,5-dichloro-benzene-1,3-disulfonic acid diamide …
Matched Categories: … Antiglaucoma Preparations and Miotics ... Genito Urinary System and Sex Hormones ... Gynecological Antiinfectives and Antiseptics …
Matched Categories: … Antiglaucoma Preparations and Miotics ... Genito Urinary System and Sex Hormones ... Gynecological Antiinfectives and Antiseptics …
Cefazolin
A semisynthetic cephalosporin analog with broad-spectrum antibiotic action due to inhibition of bacterial cell wall synthesis. It attains high serum levels and is excreted quickly via the urine.
Approved
Matched Synonyms: … sulfanyl]methyl}-8-oxo-7-[(1H-tetrazol-1-ylacetyl)amino]-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid …
Matched Iupac: … methyl}-8-oxo-7-[2-(1H-1,2,3,4-tetrazol-1-yl)acetamido]-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid …
Matched Description: … It attains high serum levels and is excreted quickly via the urine. …
Matched Iupac: … methyl}-8-oxo-7-[2-(1H-1,2,3,4-tetrazol-1-yl)acetamido]-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid …
Matched Description: … It attains high serum levels and is excreted quickly via the urine. …
Displaying drugs 2926 - 2950 of 3378 in total