Fosgemcitabine palabenamide

DB15057InvestigationalSmall molecule

NUC-1031 is under investigation in clinical trial NCT03610100 (Acelarin First Line Randomised Pancreatic Study).

Chemical structure of Fosgemcitabine palabenamide
Formula / weight
C25H27F2N4O8P · 580.482 g/mol (avg)
Code names
BIO-1031 · NUC-1031 · NUC-1031, (S)-

Resolves to

Compound
UNIII17GWP65CECAS1562406-27-2ChEMBLCHEMBL3126004
Structure
InChIKeyNHTKGYOMICWFQZ-UHFFFAOYSA-NSMILESCC(NP(=O)(OCC1OC(N2C=CC(N)=NC2=O)C(F)(F)C1O)OC1=CC=CC=C1)C(=O)OCC1=CC=CC=C1

What you can answer from here — as of April 23, 2025

39Drug interactionsStructured to mechanism, not free text
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6Clinical trialsPhase, status and sponsor resolved per trial
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Which companies are running trials of Fosgemcitabine palabenamide, in which indications and phases, and which of those programs are still active?

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