Displaying drugs 301 - 325 of 332 in total
Sucrosofate
Experimental
Matched Iupac: … [(2R,3R,4S,5S)-4-(sulfooxy)-2,5-bis[(sulfooxy)methyl]-5-{[(2R,3R,4S,5R,6R)-3,4,5-tris(sulfooxy)-6-[(sulfooxy ... )methyl]oxan-2-yl]oxy}oxolan-3-yl]oxidanesulfonic acid …
Matched Salts name: … Sucrosofate potassium …
Matched Salts name: … Sucrosofate potassium …
Methyclothiazide
A thiazide diuretic with properties similar to those of hydrochlorothiazide. (From Martindale, The Extra Pharmacopoeia, 30th ed, p825)
Withdrawn
Matched Iupac: … 6-chloro-3-(chloromethyl)-2-methyl-1,1-dioxo-3,4-dihydro-2H-1lambda6,2,4-benzothiadiazine-7-sulfonamide …
Matched Categories: … Heterocyclic Compounds, 2-Ring ... methyclothiazide and potassium …
Matched Categories: … Heterocyclic Compounds, 2-Ring ... methyclothiazide and potassium …
Tetraethylammonium
Tetraethylammonium is an experimental drug with no approved indication or marketed formulation. The only marketed drug containing tetraethylammonium was a combination drug called Fosglutamina B6, but this drug has now been discontinued. As an experimental agent, tetraethylammonium is used in its salt forms such as tetraethylammonium chloride and tetraethylammonium bromide....
Experimental
Investigational
Matched Description: … , but it is known that tetraethylammonium blocks autonomic ganglia, calcium- and voltage- activated potassium ... common use of tetraethylammonium presently is as a pharmacological research agent that blocks selective potassium …
Matched Salts cas: … 77-98-5 ... 71-91-0 ... 5574-97-0 …
Matched Categories: … MATE 1 Substrates ... MATE 2 Substrates ... Potassium Channel Blockers …
Matched Salts cas: … 77-98-5 ... 71-91-0 ... 5574-97-0 …
Matched Categories: … MATE 1 Substrates ... MATE 2 Substrates ... Potassium Channel Blockers …
Saprisartan
Saprisartan is an AT1 receptor antagonist. It is based on medications of losartan's prototypical chemical structure. The mode of (functional) AT1 receptor antagonism has been characterized as insurmountable/noncompetitive for saprisartan. It is very likely that slow dissociation kinetics from the AT1 receptor underlie insurmountable antagonism .
Experimental
Matched Iupac: … 1-({3-bromo-2-[2-(trifluoromethanesulfonamido)phenyl]-1-benzofuran-5-yl}methyl)-4-cyclopropyl-2-ethyl ... -1H-imidazole-5-carboxamide …
Matched Salts cas: … 146613-90-3 …
Matched Salts name: … Saprisartan potassium …
Matched Categories: … Heterocyclic Compounds, 2-Ring ... Angiotensin II Type 1 Receptor Blockers …
Matched Salts cas: … 146613-90-3 …
Matched Salts name: … Saprisartan potassium …
Matched Categories: … Heterocyclic Compounds, 2-Ring ... Angiotensin II Type 1 Receptor Blockers …
Calcium
Calcium plays a vital role in the anatomy, physiology and biochemistry of organisms and of the cell, particularly in signal transduction pathways. The skeleton acts as a major mineral storage site for the element and releases Ca2+ ions into the bloodstream under controlled conditions. Circulating calcium is either in the...
Nutraceutical
Matched Description: … Although calcium flow to and from the bone is neutral, about 5 mmol is turned over a day. …
Matched Mixtures name: … Cal/mag 2:1 With D ... Acti-cal/mag 2:1 + Zinc and D Caplet ... Chewable Calcium & Magnesium 2:1 Tablet …
Matched Categories: … ascorbic acid (vit C) and calcium ... etidronic acid and calcium, sequential ... risedronic acid and calcium, sequential ... zoledronic acid, calcium and colecalciferol, sequential ... risedronic acid, calcium and colecalciferol, sequential …
Matched Products: … P D M ... C P Re ... P D All …
Matched Mixtures name: … Cal/mag 2:1 With D ... Acti-cal/mag 2:1 + Zinc and D Caplet ... Chewable Calcium & Magnesium 2:1 Tablet …
Matched Categories: … ascorbic acid (vit C) and calcium ... etidronic acid and calcium, sequential ... risedronic acid and calcium, sequential ... zoledronic acid, calcium and colecalciferol, sequential ... risedronic acid, calcium and colecalciferol, sequential …
Matched Products: … P D M ... C P Re ... P D All …
Mitiglinide
Mitiglinide is a drug for the treatment of type 2 diabetes. It may stimulate insulin secretion in beta-cells by closing off ATP dependant potassium ion channels.
Investigational
Matched Iupac: … (2S)-4-[(3aR,7aS)-octahydro-1H-isoindol-2-yl]-2-benzyl-4-oxobutanoic acid …
Matched Description: … Mitiglinide is a drug for the treatment of type 2 diabetes. ... It may stimulate insulin secretion in beta-cells by closing off ATP dependant potassium ion channels. …
Matched Salts cas: … 207844-01-7 …
Matched Categories: … Heterocyclic Compounds, 2-Ring …
Matched Description: … Mitiglinide is a drug for the treatment of type 2 diabetes. ... It may stimulate insulin secretion in beta-cells by closing off ATP dependant potassium ion channels. …
Matched Salts cas: … 207844-01-7 …
Matched Categories: … Heterocyclic Compounds, 2-Ring …
Azimilide
Azimilide is an investigational class III anti-arrhythmic drug that blocks fast and slow components of the delayed rectifier cardiac potassium channels. It is not approved for use in any country, but is currently in clinical trials in the United States.
Investigational
Matched Iupac: … 1-({[5-(4-chlorophenyl)furan-2-yl]methylidene}amino)-3-[4-(4-methylpiperazin-1-yl)butyl]imidazolidine …
Matched Description: … class III anti-arrhythmic drug that blocks fast and slow components of the delayed rectifier cardiac potassium …
Matched Categories: … Heterocyclic Compounds, 1-Ring ... Cytochrome P-450 Substrates ... Cytochrome P-450 CYP3A Substrates ... Cytochrome P-450 CYP2D6 Substrates ... Cytochrome P-450 CYP3A4 Substrates …
Matched Description: … class III anti-arrhythmic drug that blocks fast and slow components of the delayed rectifier cardiac potassium …
Matched Categories: … Heterocyclic Compounds, 1-Ring ... Cytochrome P-450 Substrates ... Cytochrome P-450 CYP3A Substrates ... Cytochrome P-450 CYP2D6 Substrates ... Cytochrome P-450 CYP3A4 Substrates …
Volixibat
Volixibat, also known as SHP626 or LUM002, is an investigational drug that will potentially be used for the treatment of Non-Alcoholic Steatohepatitis (NASH). If approved for use, it will be the first available agent for the treatment of NASH.
Volixibat is a selective inhibitor of the apical sodium-dependent bile acid...
Experimental
Investigational
Matched Iupac: … {[(2R,3R,4S,5R,6R)-4-(benzyloxy)-6-[({3-[(3S,4R,5R)-3-butyl-7-(dimethylamino)-3-ethyl-4-hydroxy-1,1-dioxo ... -2,3,4,5-tetrahydro-1lambda6-benzothiepin-5-yl]phenyl}carbamoyl)amino]-3,5-dihydroxyoxan-2-yl]methoxy ... }sulfonic acid …
Matched Description: … Also known as the ileal bile acid transporter (IBAT), ASBT is primarily responsible for the enterohepatic ... Volixibat is a selective inhibitor of the apical sodium-dependent bile acid transporter (ASBT), a transmembrane …
Matched Salts cas: … 1431935-92-0 …
Matched Salts name: … Volixibat potassium …
Matched Categories: … Heterocyclic Compounds, 2-Ring …
Matched Description: … Also known as the ileal bile acid transporter (IBAT), ASBT is primarily responsible for the enterohepatic ... Volixibat is a selective inhibitor of the apical sodium-dependent bile acid transporter (ASBT), a transmembrane …
Matched Salts cas: … 1431935-92-0 …
Matched Salts name: … Volixibat potassium …
Matched Categories: … Heterocyclic Compounds, 2-Ring …
Elinogrel
A P2Y12 inhibitor and platelet aggregation inhibitor.
Investigational
Matched Iupac: … 3-[(5-chlorothiophen-2-yl)sulfonyl]-1-{4-[6-fluoro-7-(methylamino)-2,4-dioxo-1,2,3,4-tetrahydroquinazolin ... -3-yl]phenyl}urea …
Matched Salts name: … Elinogrel potassium …
Matched Categories: … Heterocyclic Compounds, 2-Ring …
Matched Salts name: … Elinogrel potassium …
Matched Categories: … Heterocyclic Compounds, 2-Ring …
Vaniprevir
Vaniprevir has been used in trials studying the treatment and diagnostic of Hepatitis C, Chronic Hepatitis C, Hepatitis C, Chronic, Chronic Hepatitis C Infection, and Chronic Genotype 1 Hepatitis C Virus Infection.
Investigational
Matched Iupac: … (1R,21S,24S)-21-tert-butyl-N-[(1R,2R)-1-[(cyclopropanesulfonyl)carbamoyl]-2-ethylcyclopropyl]-16,16-dimethyl ... -3,19,22-trioxo-2,18-dioxa-4,20,23-triazatetracyclo[21.2.1.1^{4,7}.0^{6,11}]heptacosa-6(11),7,9-triene …
Matched Description: … Hepatitis C, Chronic Hepatitis C, Hepatitis C, Chronic, Chronic Hepatitis C Infection, and Chronic Genotype 1 …
Matched Salts cas: … 1269195-08-5 …
Matched Salts name: … Vaniprevir potassium …
Matched Categories: … Heterocyclic Compounds, 2-Ring ... Amino Acids ... Amino Acids, Cyclic ... Amino Acids, Essential ... Amino Acids, Branched-Chain …
Matched Description: … Hepatitis C, Chronic Hepatitis C, Hepatitis C, Chronic, Chronic Hepatitis C Infection, and Chronic Genotype 1 …
Matched Salts cas: … 1269195-08-5 …
Matched Salts name: … Vaniprevir potassium …
Matched Categories: … Heterocyclic Compounds, 2-Ring ... Amino Acids ... Amino Acids, Cyclic ... Amino Acids, Essential ... Amino Acids, Branched-Chain …
Fimasartan
Fimasartan is an angiotensin II receptor antagonist (ARB) drug employed in the treatment of both hypertension and heart failure. It has been found to be safe when administered with hydrochlorothiazide (a diuretic) in clinical trials. Fimasartan was initially approved September 9th, 2010 in South Korea and is marketed under the...
Investigational
Matched Iupac: … 2-(2-butyl-4-methyl-6-oxo-1-{[2'-(1H-1,2,3,4-tetrazol-5-yl)-[1,1'-biphenyl]-4-yl]methyl}-1,6-dihydropyrimidin ... -5-yl)-N,N-dimethylethanethioamide …
Matched Salts cas: … 1402813-38-0 …
Matched Salts name: … Fimasartan potassium trihydrate ... Fimasartan potassium anhydrous …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Matched Salts cas: … 1402813-38-0 …
Matched Salts name: … Fimasartan potassium trihydrate ... Fimasartan potassium anhydrous …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Epitizide
Epitizide is an agent, commonly found in combination triamterene, used to produce diuresis.
Experimental
Matched Iupac: … 6-chloro-1,1-dioxo-3-{[(2,2,2-trifluoroethyl)sulfanyl]methyl}-3,4-dihydro-2H-1lambda6,2,4-benzothiadiazine ... -7-sulfonamide …
Matched Categories: … epitizide and potassium-sparing agents ... Low-Ceiling Diuretics and Potassium-Sparing Agents …
Matched Categories: … epitizide and potassium-sparing agents ... Low-Ceiling Diuretics and Potassium-Sparing Agents …
Tegoprazan
Tegoprazan (also known as CJ-12420) is a novel therapeutic developed by CJ Healthcare Corp for treating acid-related gastrointestinal diseases.[A234215, A234220] This drug is a potent and high-selective potassium-competitive acid blocker (P-CAB) with a fast onset of action and the ability to control gastric pH for a prolonged period of time.[A234215,...
Investigational
Matched Iupac: … 7-{[(4S)-5,7-difluoro-3,4-dihydro-2H-1-benzopyran-4-yl]oxy}-N,N,2-trimethyl-1H-1,3-benzodiazole-5-carboxamide …
Matched Description: … [A234215, A234220] This drug is a potent and high-selective potassium-competitive acid blocker (P-CAB ... Tegoprazan (also known as CJ-12420) is a novel therapeutic developed by CJ Healthcare Corp for treating acid-related ... to its ability to be slowly cleared from the gastric glands and exertion of effects independent of acid …
Matched Categories: … Heterocyclic Compounds, 1-Ring ... Gastric Acid Lowering Agents ... Drugs for Acid Related Disorders …
Matched Description: … [A234215, A234220] This drug is a potent and high-selective potassium-competitive acid blocker (P-CAB ... Tegoprazan (also known as CJ-12420) is a novel therapeutic developed by CJ Healthcare Corp for treating acid-related ... to its ability to be slowly cleared from the gastric glands and exertion of effects independent of acid …
Matched Categories: … Heterocyclic Compounds, 1-Ring ... Gastric Acid Lowering Agents ... Drugs for Acid Related Disorders …
Mebutizide
Experimental
Matched Iupac: … 6-chloro-3-(3-methylpentan-2-yl)-1,1-dioxo-3,4-dihydro-2H-1lambda6,2,4-benzothiadiazine-7-sulfonamide …
Matched Categories: … Heterocyclic Compounds, 2-Ring ... mebutizide and potassium-sparing agents ... Low-Ceiling Diuretics and Potassium-Sparing Agents …
Matched Categories: … Heterocyclic Compounds, 2-Ring ... mebutizide and potassium-sparing agents ... Low-Ceiling Diuretics and Potassium-Sparing Agents …
Emeramide
Emeramide has been used in trials studying the treatment of Mercury Poisoning.
Investigational
Matched Iupac: … N1,N3-bis(2-sulfanylethyl)benzene-1,3-dicarboxamide …
Matched Salts cas: … 439602-51-4 …
Matched Salts name: … Emeramide Potassium …
Matched Salts cas: … 439602-51-4 …
Matched Salts name: … Emeramide Potassium …
Clofenamide
Experimental
Matched Iupac: … 4-chlorobenzene-1,3-disulfonamide …
Matched Categories: … clofenamide and potassium …
Matched Categories: … clofenamide and potassium …
Buthiazide
Experimental
Matched Iupac: … 6-chloro-3-(2-methylpropyl)-1,1-dioxo-3,4-dihydro-2H-1lambda6,2,4-benzothiadiazine-7-sulfonamide …
Matched Categories: … Heterocyclic Compounds, 2-Ring ... butizide and potassium-sparing agents ... Low-Ceiling Diuretics and Potassium-Sparing Agents …
Matched Categories: … Heterocyclic Compounds, 2-Ring ... butizide and potassium-sparing agents ... Low-Ceiling Diuretics and Potassium-Sparing Agents …
Glyceryl stearate SE
Experimental
Matched Iupac: … potassium sodium (2R)-2,3-dihydroxypropyl octadecanoate (2S)-2,3-dihydroxypropyl octadecanoate 1,3-dihydroxypropan ... -2-yl octadecanoate dioctadecanoate …
Mefruside
Experimental
Matched Iupac: … 4-chloro-N1-methyl-N1-[(2-methyloxolan-2-yl)methyl]benzene-1,3-disulfonamide …
Matched Categories: … mefruside and potassium …
Matched Categories: … mefruside and potassium …
Desoxycorticosterone pivalate
Desoxycorticosterone pivalate is a mineralocorticoid hormone and an analog of desoxycorticosterone. It is white, odorless, and stable in air. It is practically insoluble in water, sparingly soluble in acetone, slightly soluble in methanol, ether and vegetable oils. Federal (U.S.A.) law restricts this drug to use by or on the order...
Experimental
Vet approved
Matched Iupac: … 2-[(1S,2R,10S,11S,14S,15S)-2,15-dimethyl-5-oxotetracyclo[8.7.0.0²,⁷.0¹¹,¹⁵]heptadec-6-en-14-yl]-2-oxoethyl …
Matched Categories: … Cytochrome P-450 Substrates ... Cytochrome P-450 CYP3A Substrates ... Cytochrome P-450 CYP3A4 Substrates …
Matched Categories: … Cytochrome P-450 Substrates ... Cytochrome P-450 CYP3A Substrates ... Cytochrome P-450 CYP3A4 Substrates …
Tripamide
Experimental
Matched Iupac: … N-[(1R,2R,6S,7S)-4-azatricyclo[5.2.1.0^{2,6}]decan-4-yl]-4-chloro-3-sulfamoylbenzamide …
Matched Categories: … Heterocyclic Compounds, 2-Ring ... Sodium Potassium Chloride Symporter Inhibitors …
Matched Categories: … Heterocyclic Compounds, 2-Ring ... Sodium Potassium Chloride Symporter Inhibitors …
Canrenone
Canrenone has been used in trials studying the diagnostic of Heart Failure.
Investigational
Matched Iupac: … [a]phenanthrene-1,2'-oxolane]-5',7-dione ... (1R,3aS,3bR,9aR,9bS,11aS)-9a,11a-dimethyl-2,3,3a,3b,7,8,9,9a,9b,10,11,11a-dodecahydrospiro[cyclopenta …
Matched Categories: … Potassium-Sparing Diuretics …
Matched Categories: … Potassium-Sparing Diuretics …
Clopamide
Clopamide is an oral diuretic agent with antihypertensive activity. Like thiazide diuretics, it has an aromatic sulfonamide base but with no double-ring structure.
Experimental
Matched Iupac: … 4-chloro-N-[(2R,6S)-2,6-dimethylpiperidin-1-yl]-3-sulfamoylbenzamide …
Matched Categories: … clopamide and potassium ... Heterocyclic Compounds, 1-Ring …
Matched Categories: … clopamide and potassium ... Heterocyclic Compounds, 1-Ring …
Linsidomine
Experimental
Matched Iupac: … 5-azanidyl-3-(morpholin-4-yl)-1,2,3lambda5-oxadiazol-3-ylium …
Matched Salts cas: … 16142-27-1 …
Matched Categories: … Heterocyclic Compounds, 1-Ring ... Sodium-Potassium-Exchanging ATPase, antagonists & inhibitors …
Matched Salts cas: … 16142-27-1 …
Matched Categories: … Heterocyclic Compounds, 1-Ring ... Sodium-Potassium-Exchanging ATPase, antagonists & inhibitors …
Linopirdine
Experimental
Matched Iupac: … 1-phenyl-3,3-bis[(pyridin-4-yl)methyl]-2,3-dihydro-1H-indol-2-one …
Matched Categories: … Potassium Channel Blockers ... Heterocyclic Compounds, 1-Ring ... Heterocyclic Compounds, 2-Ring …
Matched Categories: … Potassium Channel Blockers ... Heterocyclic Compounds, 1-Ring ... Heterocyclic Compounds, 2-Ring …
Displaying drugs 301 - 325 of 332 in total