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Displaying drugs 326 - 350 of 375 in total
Flunixin is a non-steroidal anti-inflammatory drug for use in pigs, cattle and horses. It exerts analgesic and antipyretic effects. This drug is often prepared for use in meglumine salt form. Flunixin is regulated in the United States by the Food and Drug Administration (FDA) and must be prescribed by a...
Vet approved
Matched Synonyms: … 2-((2-methyl-3-(trifluoromethyl)phenyl)amino)-3-pyridinecarboxylic acid …
Matched Iupac: … 2-{[2-methyl-3-(trifluoromethyl)phenyl]amino}pyridine-3-carboxylic acid …
Matched Description: … This drug is often prepared for use in meglumine salt form. ... Flunixin is regulated in the United States by the Food and Drug Administration (FDA) and must be prescribed ... It exerts analgesic and antipyretic effects. …
Matched Categories: … Non COX-2 selective NSAIDS …
Adinazolam (Deracyn®) is a benzodiazepine derivative with anxiolytic, anticonvulsant, sedative, and antidepressant properties. Adinazolam was first developed to enhance the antidepressant effects of alprazolam. It has never been approved by the FDA for clinical use.
Experimental
Matched Synonyms: … 8-Chloro-1-((dimethylamino)methyl)-6-phenyl-4H-s-triazolo(4,3-a)(1,4)benzodiazepine …
Matched Iupac: … ({12-chloro-9-phenyl-2,4,5,8-tetraazatricyclo[8.4.0.0^{2,6}]tetradeca-1(10),3,5,8,11,13-hexaen-3-yl}methyl
Matched Description: … Adinazolam (Deracyn®) is a benzodiazepine derivative with anxiolytic, anticonvulsant, sedative, and antidepressant …
Matched Categories: … Heterocyclic Compounds, 2-Ring ... Benzodiazepines and benzodiazepine derivatives …
Experimental
Matched Synonyms: … L-Glutamic acid, N-[4-[[[(6R)-2-amino-5-formyl-3,4,5,6,7,8-hexahydro-4-oxo-6-pteridinyl]methyl]amino] ... N-{[4-({[(6R)-2-amino-5-formyl-4-oxo-1,4,5,6,7,8-hexahydropteridin-6-yl]methyl}amino)phenyl]carbonyl} ... (6R,2'S)-Folinic acid …
Matched Iupac: … (2S)-2-{[4-({[(6R)-2-amino-5-formyl-4-oxo-1,4,5,6,7,8-hexahydropteridin-6-yl]methyl}amino)phenyl]formamido …
Matched Categories: … Folic Acid and Derivatives …
Bevantolol is a beta-1 adrenoceptor antagonist that has been shown to be as effective as other beta blockers for the treatment of angina pectoris and hypertension. Mechanism of Action Animal experiments confirm both agonist and antagonist effects on alpha-receptors, in addition to antagonist activity at beta-1 receptors.
Experimental
Matched Synonyms: … 1-((2-(3,4-dimethoxyphenyl)ethyl)amino)-3-(3-methylphenoxy)-2-propanol ... 1-[2-(3,4-Dimethoxy-phenyl)-ethylamino]-3-m-tolyloxy-propan-2-ol ... 1-(3,4-dimethoxyphenethylamino)-3-(m-tolyloxy)-2-propanol …
Matched Iupac: … 1-{[2-(3,4-dimethoxyphenyl)ethyl]amino}-3-(3-methylphenoxy)propan-2-ol …
Matched Description: … that has been shown to be as effective as other beta blockers for the treatment of angina pectoris and ... Mechanism of Action Animal experiments confirm both agonist and antagonist effects on alpha-receptors …
Matched Categories: … bevantolol and thiazides ... Beta Blocking Agents and Thiazides ... Beta Blocking Agents, Selective, and Thiazides …
Matched Products: … BETA FORM
Non-methylated, competitive, and irreversible inhibitor of caspase 1, as well as other caspases,1 which can be used directly with purified enzymes. It does not require an esterase to hydrolyze the O-methyl ester like the cell-permeable form, Z-Val-Ala-Asp(O-Me) fluoromethyl ketone.
Experimental
Matched Synonyms: … N-[(Benzyloxy)carbonyl]-L-valyl-N-[(2S)-1-carboxy-4-fluoro-3-oxo-2-butanyl]-L-alaninamide …
Matched Iupac: … (3S)-3-[(2S)-2-[(2S)-2-{[(benzyloxy)carbonyl]amino}-3-methylbutanamido]propanamido]-5-fluoro-4-oxopentanoic …
Matched Description: … It does not require an esterase to hydrolyze the O-methyl ester like the cell-permeable form, Z-Val-Ala-Asp ... Non-methylated, competitive, and irreversible inhibitor of caspase 1, as well as other caspases,1 which …
Matched Categories: … Amino Acids, Peptides, and Proteins …
N-Formylmethionine is effective in the initiation of protein synthesis. The initiating methionine residue enters the ribosome as N-formylmethionyl tRNA. This process occurs in Escherichia coli and other bacteria as well as in the mitochondria of eucaryotic cells.
Experimental
Matched Synonyms: … (2S)-2-(formylamino)-4-(methylthio)butanoic acid …
Matched Iupac: … (2S)-2-formamido-4-(methylsulfanyl)butanoic acid …
Matched Description: … This process occurs in Escherichia coli and other bacteria as well as in the mitochondria of eucaryotic …
Matched Categories: … Amino Acids, Peptides, and Proteins …
A nucleoside analog with anti-hepatitis C virus (HCV) activity. Upon phosphorylation into its 5-triphosphate form, this metabolite inhibits viral RNA chain elongation and viral RNA-dependent RNA polymerase activity. This blocks viral production of HCV RNA and thus viral replication.
Experimental
Matched Synonyms: … 2'C-Me-C ... 2'-C-Mecytosin …
Matched Name: … 2'-C-methylcytidine …
Matched Iupac: … 4-amino-1-[(2R,3R,4R,5R)-3,4-dihydroxy-5-(hydroxymethyl)-3-methyloxolan-2-yl]-1,2-dihydropyrimidin-2- …
Matched Description: … A nucleoside analog with anti-hepatitis C virus (HCV) activity. ... Upon phosphorylation into its 5-triphosphate form, this metabolite inhibits viral RNA chain elongation ... and viral RNA-dependent RNA polymerase activity. …
Matched Categories: … Nucleic Acids, Nucleotides, and Nucleosides …
CNS 5161 is a blocker of the NMDA ion channel and has completed Phase IIa proof of concept clinical trials as a novel compound for the treatment of neuropathic pain.
Investigational
Matched Iupac: … (E)-N''-[2-chloro-5-(methylsulfanyl)phenyl]-N-methyl-N-[3-(methylsulfanyl)phenyl]guanidine …
Matched Description: … CNS 5161 is a blocker of the NMDA ion channel and has completed Phase IIa proof of concept clinical trials …
Benidipine has the formula 1,4-dihydro-2,6-dimethyl-4-(3-nitrophenyl)-3,5-pyridine-dicarboxylic acid methyl 1-(phenylmethyl)-3-piperidinyl ester hydrochloride. It is a synthetic dihydropyridine derivative that has anti-hypertensive and anti-anginal actions. It was originated in Japan by Kyowa Hakko, it is submitted for FDA approval and it is currently available in some Asian countries like India and Japan.[L1385, L1386]
Experimental
Matched Iupac: … 3-(3R)-1-benzylpiperidin-3-yl 5-methyl (4R)-2,6-dimethyl-4-(3-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylate …
Matched Description: … Benidipine has the formula 1,4-dihydro-2,6-dimethyl-4-(3-nitrophenyl)-3,5-pyridine-dicarboxylic acid methyl ... available in some Asian countries like India and Japan. ... It is a synthetic dihydropyridine derivative that has anti-hypertensive and anti-anginal actions. …
Matched Categories: … Calcium-Regulating Hormones and Agents …
Experimental
Matched Synonyms: … 2-Butenal ... trans-2-butenal ... trans-but-2-enal …
Matched Iupac: … (2E)-but-2-enal …
Experimental
Matched Synonyms: … 4-[2-Acetylamino-2-(1-biphenyl-4-ylmethyl-2-oxo-azepan-3-ylcarbamoyl)-ethyl]-2-formyl-benzoic acid …
Matched Iupac: … 4-[(2S)-2-{[(3S)-1-({[1,1'-biphenyl]-4-yl}methyl)-2-oxoazepan-3-yl]carbamoyl}-2-acetamidoethyl]-2-formylbenzoic …
The 3-O-valine ester prodrug of the nucleoside analog 2'-C-methylcytidine with anti-hepatitis C virus (HCV) activity. Upon administration, valopicitabine is converted into 2'-C-methylcytidine; upon phosphorylation into its 5-triphosphate form, this metabolite inhibits viral RNA chain elongation and viral RNA-dependent RNA polymerase activity. This blocks viral production of HCV RNA and thus...
Experimental
Matched Synonyms: … 2'-C-methylcytidine 3'-O-L-valinyl ester …
Matched Iupac: … (2R,3R,4R,5R)-5-(4-amino-2-oxo-1,2-dihydropyrimidin-1-yl)-4-hydroxy-2-(hydroxymethyl)-4-methyloxolan- ... 3-yl (2S)-2-amino-3-methylbutanoate …
Matched Description: … its 5-triphosphate form, this metabolite inhibits viral RNA chain elongation and viral RNA-dependent ... The 3-O-valine ester prodrug of the nucleoside analog 2'-C-methylcytidine with anti-hepatitis C virus ... Upon administration, valopicitabine is converted into 2'-C-methylcytidine; upon phosphorylation into …
Matched Categories: … Nucleic Acids, Nucleotides, and Nucleosides …
RU84687 is a subnanomolar and Src SH2 selective binder.
Experimental
Matched Synonyms: … N-acetyl-N-[1-(1,1'-biphenyl-4-ylmethyl)-2-oxoazepan-3-yl]-3-formyl-O-phosphonotyrosinamide …
Matched Iupac: … {4-[(2S)-2-{[(3S)-1-({[1,1'-biphenyl]-4-yl}methyl)-2-oxoazepan-3-yl]carbamoyl}-2-acetamidoethyl]-2-formylphenoxy …
Matched Description: … RU84687 is a subnanomolar and Src SH2 selective binder. …
Candesartan is an angiotensin-receptor blocker (ARB) that may be used alone or with other agents to treat hypertension. It is available as a prodrug in the form of candesartan cilexetil.
Experimental
Matched Synonyms: … 2-ethoxy-1-(p-(o-1H-tetrazol-5-ylphenyl)benzyl)-7-benzimidazolecarboxylic acid …
Matched Iupac: … 2-ethoxy-1-{[2'-(1H-1,2,3,4-tetrazol-5-yl)-[1,1'-biphenyl]-4-yl]methyl}-1H-1,3-benzodiazole-7-carboxylic …
Matched Description: … It is available as a prodrug in the form of [candesartan cilexetil]. …
Matched Categories: … Angiotensin 2 Receptor Blocker ... Heterocyclic Compounds, 2-Ring ... Angiotensin II Type 2 Receptor Blockers ... candesartan and diuretics ... candesartan and amlodipine …
Experimental
Matched Iupac: … (1S)-1-[(3,4,5-trimethoxyphenyl)methyl]-1,2,3,4-tetrahydroisoquinoline-6,7-diol …
Matched Categories: … Heterocyclic Compounds, 2-Ring ... Selective Beta 2-adrenergic Agonists …
Phosphocreatine - or creatine phosphate - is the phosphorylated form of creatine. It is primarily found endogenously in the skeletal muscles of vertebrates where it serves a critical role as a rapidly acting energy buffer for muscle cell actions like contractions via its ability to regenerate adenosine triphosphate (ATP) from...
Nutraceutical
Matched Iupac: … 2-(N-methyl-N'-phosphonocarbamimidamido)acetic acid …
Matched Description: … Phosphocreatine - or creatine phosphate - is the phosphorylated form of creatine. …
Matched Categories: … Amino Acids, Peptides, and Proteins …
An alkaloid obtained from the betel nut (Areca catechu), fruit of a palm tree. It is an agonist at both muscarinic and nicotinic acetylcholine receptors. It is used in the form of various salts as a ganglionic stimulant, a parasympathomimetic, and a vermifuge, especially in veterinary practice. It has been...
Experimental
Matched Iupac: … methyl 1-methyl-1,2,5,6-tetrahydropyridine-3-carboxylate …
Matched Description: … It is used in the form of various salts as a ganglionic stimulant, a parasympathomimetic, and a vermifuge ... It is an agonist at both muscarinic and nicotinic acetylcholine receptors. …
A hallucinogen formerly used as a veterinary anesthetic, and briefly as a general anesthetic for humans. Phencyclidine is similar to ketamine in structure and in many of its effects. Like ketamine, it can produce a dissociative state. It exerts its pharmacological action through inhibition of NMDA receptors (receptors, N-methyl-D-aspartate). As...
Illicit
Matched Description: … It exerts its pharmacological action through inhibition of NMDA receptors (receptors, N-methyl-D-aspartate ... As a drug of abuse, it is known as PCP and Angel Dust. ... Phencyclidine is similar to ketamine in structure and in many of its effects. …
Oxabolone cipionate is the C17β cypionate ester and a prodrug of DB01500. A synthetic anabolic-androgenic (AAS) steroid, it is a derivative of 19-nortestosterone (nandrolone). It is considered as a performance enhancing drug thus is prohibited from use in sports.
Experimental
Matched Iupac: … (1S,2R,10R,11S,14S,15S)-6-hydroxy-15-methyl-5-oxotetracyclo[8.7.0.0²,⁷.0¹¹,¹⁵]heptadec-6-en-14-yl 3-cyclopentylpropanoate …
Matched Description: … Oxabolone cipionate is the C17β cypionate ester and a prodrug of [DB01500]. …
Matched Categories: … Alimentary Tract and Metabolism ... Hormones, Hormone Substitutes, and Hormone Antagonists …
Experimental
Matched Name: … N-[(2R,3S)-1-((2S)-2-{[(CYCLOPENTYLAMINO)CARBONYL]AMINO}-3-METHYLBUTANOYL)-2-(1-FORMYL-1-CYCLOBUTYL)PYRROLIDINYL …
Matched Iupac: … N-[(2R,3S)-1-[(2S)-2-[(cyclopentylcarbamoyl)amino]-3-methylbutanoyl]-2-(1-formylcyclobutyl)pyrrolidin …
Experimental
Matched Name: … HYDROXY[3-(6-METHYLPYRIDIN-2-YL)PROPYL]FORMAMIDE …
Matched Iupac: … N-hydroxy-N-[3-(6-methylpyridin-2-yl)propyl]formamide …
Investigational
Matched Iupac: … (1R,3R)-5-{2-[(1R,3aR,4E,7aR)-1-[(2R)-6-hydroxy-6-methylhept-4-yn-2-yl]-7a-methyl-octahydro-1H-inden- …
Matched Categories: … Vitamin D and Analogues …
Detomidine is an α2-adrenergic agonist that is used as a horse sedative. Normally, it is administered in the salt form, detomidine hydrochloride. This drug is prescribed by veterinarians and is marketed as Dormosedan. Currently, it is only approved by the FDA for use in horses but has been studied for...
Vet approved
Matched Iupac: … 5-[(2,3-dimethylphenyl)methyl]-1H-imidazole …
Matched Description: … Normally, it is administered in the salt form, detomidine hydrochloride. ... This drug is prescribed by veterinarians and is marketed as _Dormosedan_. …
Matched Categories: … Hypnotics and Sedatives ... Adrenergic alpha-2 Receptor Agonists …
N-methylmesoporphyrin is a solid. This compound belongs to the porphyrins. These are compounds containing a fundamental skeleton of four pyrrole nuclei united through the alpha-positions by four methine groups to form a macrocyclic structure. This medication is known to target ferrochelatase.
Experimental
Matched Iupac: … 3-[20-(2-carboxyethyl)-10,15-diethyl-5,9,14,19,23-pentamethyl-21,22,23,24-tetraazapentacyclo[16.2.1.1 …
Matched Description: … fundamental skeleton of four pyrrole nuclei united through the alpha-positions by four methine groups to form
Levopropoxyphene is a stereoisomer of propoxyphene in the form of 2S, 3R enantiomer. It was sold as an antitussive, but it was removed from the market in the 70s. Levopropoxyphene was developed by Lilly and FDA approved on March 21st, 1962. This drug presented different dosages and it was administered...
Withdrawn
Matched Iupac: … (2R,3S)-4-(dimethylamino)-3-methyl-1,2-diphenylbutan-2-yl propanoate …
Matched Description: … Levopropoxyphene is a stereoisomer of propoxyphene in the form of 2S, 3R enantiomer. ... [T133] Levopropoxyphene was developed by Lilly and FDA approved on March 21st, 1962. ... This drug presented different dosages and it was administered as a capsule or suspension. …
Displaying drugs 326 - 350 of 375 in total