Displaying drugs 4451 - 4475 of 5288 in total
Efzofitimod
Efzofitimod (ATYR1923) is a fusion protein comprised of the immuno-modulatory domain of histidyl tRNA synthetase fused to the FC region of a human antibody. It is a selective modulator of neuropilin-2 that downregulates the innate and adaptive immune response in inflammatory disease states.
Investigational
Matched Synonyms: … Human IgG1Fc- iMod domain (amino acids 2-60) of human HARS fusion protein …
Matched Description: … It is a selective modulator of neuropilin-2 that downregulates the innate and adaptive immune response ... synthetase fused to the FC region of a human antibody. ... Efzofitimod (ATYR1923) is a fusion protein comprised of the immuno-modulatory domain of histidyl tRNA …
Matched Description: … It is a selective modulator of neuropilin-2 that downregulates the innate and adaptive immune response ... synthetase fused to the FC region of a human antibody. ... Efzofitimod (ATYR1923) is a fusion protein comprised of the immuno-modulatory domain of histidyl tRNA …
Chlorthalidone
Chlorthalidone is a thiazide-like diuretic used for the treatment of hypertension and for management of edema caused by conditions such as heart failure or renal impairment. Chlorthalidone improves blood pressure and swelling by preventing water absorption from the kidneys through inhibition of the Na+/Cl− symporter in the distal convoluted tubule...
Approved
Matched Synonyms: … 2-chloro-5-(1-hydroxy-3-oxo-1-isoindolinyl)benzenesulfonamide ... 2-chloro-5-(2,3-dihydro-1-hydroxy-3-oxo-1H-isoindol-1-yl)benzenesulfonamide …
Matched Iupac: … 2-chloro-5-(1-hydroxy-3-oxo-2,3-dihydro-1H-isoindol-1-yl)benzene-1-sulfonamide …
Matched Description: … Chlorthalidone is a thiazide-like diuretic used for the treatment of hypertension and for management ... and demonstrated that chlorthalidone had a statistically significant lower incidence of stroke and heart ... [A173884, A173887] Further studies have indicated that low-dose thiazides are as good as, and in some …
Matched Mixtures name: … TRI NORMIN 50 ... TENORET 50 TABLET ... PRETENOL C 50 TABLET …
Matched Categories: … chlortalidone and potassium ... chlortalidone and potassium-sparing agents ... Low-Ceiling Diuretics and Potassium-Sparing Agents ... Sodium Chloride Symporter Inhibitors ... Thiazide-like Diuretic …
Matched Products: … Apo-chlorthalidone ... Apo Chlorthalidone Tab 100mg ... HYGROTON 50 …
Matched Iupac: … 2-chloro-5-(1-hydroxy-3-oxo-2,3-dihydro-1H-isoindol-1-yl)benzene-1-sulfonamide …
Matched Description: … Chlorthalidone is a thiazide-like diuretic used for the treatment of hypertension and for management ... and demonstrated that chlorthalidone had a statistically significant lower incidence of stroke and heart ... [A173884, A173887] Further studies have indicated that low-dose thiazides are as good as, and in some …
Matched Mixtures name: … TRI NORMIN 50 ... TENORET 50 TABLET ... PRETENOL C 50 TABLET …
Matched Categories: … chlortalidone and potassium ... chlortalidone and potassium-sparing agents ... Low-Ceiling Diuretics and Potassium-Sparing Agents ... Sodium Chloride Symporter Inhibitors ... Thiazide-like Diuretic …
Matched Products: … Apo-chlorthalidone ... Apo Chlorthalidone Tab 100mg ... HYGROTON 50 …
FG-2216
A orally active prolyl-hydroxylase inhibitor which can stabilize hypoxia-inducible transcription factor independent of oxygen availability.
Investigational
Matched Synonyms: … (((1-Chloro-4-hydroxyisoquinolin-3-yl)carbonyl)amino)acetic acid …
Matched Iupac: … 2-[(1-chloro-4-hydroxyisoquinolin-3-yl)formamido]acetic acid …
Matched Description: … A orally active prolyl-hydroxylase inhibitor which can stabilize hypoxia-inducible transcription factor …
Matched Iupac: … 2-[(1-chloro-4-hydroxyisoquinolin-3-yl)formamido]acetic acid …
Matched Description: … A orally active prolyl-hydroxylase inhibitor which can stabilize hypoxia-inducible transcription factor …
Uridine-5'-Diphosphate-N-Acetylmuramoyl-L-Alanine-D-Glutamate
Experimental
Matched Name: … Uridine-5'-Diphosphate-N-Acetylmuramoyl-L-Alanine-D-Glutamate …
Matched Iupac: … hydroxy-6-(hydroxymethyl)oxan-4-yl]oxy}propanamido]propanamido]pentanedioic acid ... (2R)-2-[(2S)-2-[(2R)-2-{[(2R,3R,4R,5S,6R)-2-({[({[(2R,3S,4R,5R)-5-(2,4-dioxo-1,2,3,4-tetrahydropyrimidin ... 1-yl)-3,4-dihydroxyoxolan-2-yl]methoxy}(hydroxy)phosphoryl)oxy](hydroxy)phosphoryl}oxy)-3-acetamido-5- …
Matched Iupac: … hydroxy-6-(hydroxymethyl)oxan-4-yl]oxy}propanamido]propanamido]pentanedioic acid ... (2R)-2-[(2S)-2-[(2R)-2-{[(2R,3R,4R,5S,6R)-2-({[({[(2R,3S,4R,5R)-5-(2,4-dioxo-1,2,3,4-tetrahydropyrimidin ... 1-yl)-3,4-dihydroxyoxolan-2-yl]methoxy}(hydroxy)phosphoryl)oxy](hydroxy)phosphoryl}oxy)-3-acetamido-5- …
5-[Bis-2(Chloro-Ethyl)-Amino]-2,4-Dintro-Benzamide
Experimental
Matched Name: … 5-[Bis-2(Chloro-Ethyl)-Amino]-2,4-Dintro-Benzamide …
Matched Iupac: … 5-[bis(2-chloroethyl)amino]-2,4-dinitrobenzamide …
Matched Iupac: … 5-[bis(2-chloroethyl)amino]-2,4-dinitrobenzamide …
Compound 5, 2-(Naphthalen-1-Yl-Oxalyl-Amino)-Benzoicacid
Experimental
Matched Name: … Compound 5, 2-(Naphthalen-1-Yl-Oxalyl-Amino)-Benzoicacid …
Matched Iupac: … 2-[1-carboxy-N-(naphthalen-1-yl)formamido]benzoic acid …
Matched Iupac: … 2-[1-carboxy-N-(naphthalen-1-yl)formamido]benzoic acid …
4-S-Glutathionyl-5-pentyl-tetrahydro-furan-2-ol
Experimental
Matched Name: … 4-S-Glutathionyl-5-pentyl-tetrahydro-furan-2-ol …
Matched Iupac: … }ethyl]carbamoyl}butanoic acid ... (2S)-2-amino-4-{[(1R)-1-[(carboxymethyl)carbamoyl]-2-{[(2R,3S,5R)-5-hydroxy-2-pentyloxolan-3-yl]sulfanyl …
Matched Iupac: … }ethyl]carbamoyl}butanoic acid ... (2S)-2-amino-4-{[(1R)-1-[(carboxymethyl)carbamoyl]-2-{[(2R,3S,5R)-5-hydroxy-2-pentyloxolan-3-yl]sulfanyl …
N-ALLYL-5-AMIDINOAMINOOXY-PROPYLOXY-3-CHLORO-N-CYCLOPENTYLBENZAMIDE
Experimental
Matched Name: … N-ALLYL-5-AMIDINOAMINOOXY-PROPYLOXY-3-CHLORO-N-CYCLOPENTYLBENZAMIDE …
Matched Iupac: … 3-[3-(carbamimidamidooxy)propoxy]-5-chloro-N-cyclopentyl-N-(prop-2-en-1-yl)benzamide …
Matched Iupac: … 3-[3-(carbamimidamidooxy)propoxy]-5-chloro-N-cyclopentyl-N-(prop-2-en-1-yl)benzamide …
(3S)-1-CYCLOHEXYL-5-OXO-N-PHENYLPYRROLIDINE-3-CARBOXAMIDE
Experimental
Matched Name: … (3S)-1-CYCLOHEXYL-5-OXO-N-PHENYLPYRROLIDINE-3-CARBOXAMIDE …
Matched Iupac: … (3S)-1-cyclohexyl-5-oxo-N-phenylpyrrolidine-3-carboxamide …
Matched Iupac: … (3S)-1-cyclohexyl-5-oxo-N-phenylpyrrolidine-3-carboxamide …
5-CYANO-N-(2,5-DIMETHOXYBENZYL)-6-ETHOXYPYRIDINE-2-CARBOXAMIDE
Experimental
Matched Name: … 5-CYANO-N-(2,5-DIMETHOXYBENZYL)-6-ETHOXYPYRIDINE-2-CARBOXAMIDE …
Matched Iupac: … 5-cyano-N-[(2,5-dimethoxyphenyl)methyl]-6-ethoxypyridine-2-carboxamide …
Matched Iupac: … 5-cyano-N-[(2,5-dimethoxyphenyl)methyl]-6-ethoxypyridine-2-carboxamide …
3-CHLORO-2-(4-HYDROXYPHENYL)-2H-INDAZOL-5-OL
Experimental
Matched Name: … 3-CHLORO-2-(4-HYDROXYPHENYL)-2H-INDAZOL-5-OL …
Matched Iupac: … 3-chloro-2-(4-hydroxyphenyl)-2H-indazol-5-ol …
Matched Iupac: … 3-chloro-2-(4-hydroxyphenyl)-2H-indazol-5-ol …
2-(1,3-thiazol-4-yl)-1H-benzimidazole-5-sulfonamide
Experimental
Matched Name: … 2-(1,3-thiazol-4-yl)-1H-benzimidazole-5-sulfonamide …
Matched Iupac: … 2-(1,3-thiazol-4-yl)-1H-1,3-benzodiazole-5-sulfonamide …
Matched Iupac: … 2-(1,3-thiazol-4-yl)-1H-1,3-benzodiazole-5-sulfonamide …
Cerulenin
Cerulenin is an antifungal agent whose activity interferes with or otherwise acts to prevent the formation of fatty acids and sterols. In fatty acid synthesis, reported to bind in equimolar ratio to b-keto-acyl-ACP synthase. In sterol synthesis, inhibits HMG-CoA synthetase activity. It is also shown to inhibit feeding and induce...
Experimental
Matched Synonyms: … (2R,3S)-3-((4E,7E)-Nona-4,7-dienoyl)-oxirane-2-carboxylic acid amide …
Matched Iupac: … (2R,3S)-3-[(4E,7E)-nona-4,7-dienoyl]oxirane-2-carboximidic acid …
Matched Description: … of fatty acids and sterols. ... It is also shown to inhibit feeding and induce dramatic weight loss in mice. ... In fatty acid synthesis, reported to bind in equimolar ratio to b-keto-acyl-ACP synthase. …
Matched Categories: … Fatty Acid Synthesis Inhibitors …
Matched Iupac: … (2R,3S)-3-[(4E,7E)-nona-4,7-dienoyl]oxirane-2-carboximidic acid …
Matched Description: … of fatty acids and sterols. ... It is also shown to inhibit feeding and induce dramatic weight loss in mice. ... In fatty acid synthesis, reported to bind in equimolar ratio to b-keto-acyl-ACP synthase. …
Matched Categories: … Fatty Acid Synthesis Inhibitors …
Benzonatate
Benzonatate is an oral antitussive drug used in the relief and suppression of cough in patients older than ten years of age. Currently, benzonatate is the only non-narcotic antitussive available as a prescription drug. It works to reduce the activity of cough reflex by desensitizing the tissues of the lungs...
Approved
Matched Synonyms: … p-butylaminobenzoic acid ω-O-methylnonaethyleneglycol ester ... 4-(butylamino)benzoic acid 3,6,9,12,15,18,21,24,27-nonaoxaoctacos-1-yl ester …
Matched Description: … Benzonatate is an oral antitussive drug used in the relief and suppression of cough in patients older ... toxicity and overdose, especially in children. ... class (such as [procaine] and [tetracaine]), benzonatate exhibits anesthetic or numbing action. …
Matched Categories: … Cough and Cold Preparations …
Matched Description: … Benzonatate is an oral antitussive drug used in the relief and suppression of cough in patients older ... toxicity and overdose, especially in children. ... class (such as [procaine] and [tetracaine]), benzonatate exhibits anesthetic or numbing action. …
Matched Categories: … Cough and Cold Preparations …
Sofosbuvir
Sofosbuvir (tradename Sovaldi) is a direct acting antiviral medication used as part of combination therapy to treat chronic Hepatitis C, an infectious liver disease caused by infection with Hepatitis C Virus (HCV). HCV is a single-stranded RNA virus that is categorized into nine distinct genotypes, with genotype 1 being the...
Approved
Matched Synonyms: … S)-Isopropyl 2-((S)-(((2R,3R,4R,5R)-5-(2,4-dioxo-3,4- dihydropyrimidin-1(2H)-yl)-4-fluoro-3-hydroxy-4 …
Matched Iupac: … propan-2-yl (2S)-2-{[(S)-{[(2R,3R,4R,5R)-5-(2,4-dioxo-1,2,3,4-tetrahydropyrimidin-1-yl)-4-fluoro-3-hydroxy …
Matched Description: … Both Canadian and American guidelines list Epclusa as a first line recommendation for all genotypes of ... achieve a SVR between 93 and 99% after 12 weeks of treatment [A7535]. ... being the most common in the United States, and affecting 72% of all chronic HCV patients [L852]. …
Matched Mixtures name: … Ledipasvir and Sofosbuvir ... Sofosbuvir and Velpatasvir ... MYHEP ALL …
Matched Categories: … Nucleic Acids, Nucleotides, and Nucleosides ... sofosbuvir and ledipasvir ... sofosbuvir and velpatasvir ... sofosbuvir, velpatasvir and voxilaprevir ... Drugs that are Mainly Renally Excreted …
Matched Iupac: … propan-2-yl (2S)-2-{[(S)-{[(2R,3R,4R,5R)-5-(2,4-dioxo-1,2,3,4-tetrahydropyrimidin-1-yl)-4-fluoro-3-hydroxy …
Matched Description: … Both Canadian and American guidelines list Epclusa as a first line recommendation for all genotypes of ... achieve a SVR between 93 and 99% after 12 weeks of treatment [A7535]. ... being the most common in the United States, and affecting 72% of all chronic HCV patients [L852]. …
Matched Mixtures name: … Ledipasvir and Sofosbuvir ... Sofosbuvir and Velpatasvir ... MYHEP ALL …
Matched Categories: … Nucleic Acids, Nucleotides, and Nucleosides ... sofosbuvir and ledipasvir ... sofosbuvir and velpatasvir ... sofosbuvir, velpatasvir and voxilaprevir ... Drugs that are Mainly Renally Excreted …
Ilorasertib
Ilorasertib has been used in trials studying the treatment of Myelodysplasia, Solid Neoplasm, Advanced Cancers, Advanced Solid Tumors, and Acute Myelogenous Leukemia, among others.
Investigational
Matched Synonyms: … 1-(4-{4-amino-7-[1-(2-hydroxyethyl)-1H-pyrazol-4-yl]thieno[3,2-c]pyridine-3-yl}phenyl)-3-(3-fluorophenyl …
Matched Description: … studying the treatment of Myelodysplasia, Solid Neoplasm, Advanced Cancers, Advanced Solid Tumors, and …
Matched Description: … studying the treatment of Myelodysplasia, Solid Neoplasm, Advanced Cancers, Advanced Solid Tumors, and …
{4-[(2s,4e)-2-(1,3-Benzothiazol-2-Yl)-2-(1h-1,2,3-Benzotriazol-1-Yl)-5-Phenylpent-4-Enyl]Phenyl}(Difluoro)Methylphosphonic Acid
Experimental
Matched Name: … )Methylphosphonic Acid ... {4-[(2s,4e)-2-(1,3-Benzothiazol-2-Yl)-2-(1h-1,2,3-Benzotriazol-1-Yl)-5-Phenylpent-4-Enyl]Phenyl}(Difluoro …
Matched Iupac: … )phosphonic acid ... ({4-[(2R,4E)-2-(1,3-benzothiazol-2-yl)-2-(1H-1,2,3-benzotriazol-1-yl)-5-phenylpent-4-en-1-yl]phenyl}difluoromethyl …
Matched Iupac: … )phosphonic acid ... ({4-[(2R,4E)-2-(1,3-benzothiazol-2-yl)-2-(1H-1,2,3-benzotriazol-1-yl)-5-phenylpent-4-en-1-yl]phenyl}difluoromethyl …
2-{4-[2-(2-AMINO-4-OXO-4,7-DIHYDRO-3H-PYRROLO[2,3-D]PYRIMIDIN-5-YL)-ETHYL]-BENZOYLAMINO}-3-METHYL-BUTYRIC ACID
Experimental
Matched Name: … ACID ... 2-{4-[2-(2-AMINO-4-OXO-4,7-DIHYDRO-3H-PYRROLO[2,3-D]PYRIMIDIN-5-YL)-ETHYL]-BENZOYLAMINO}-3-METHYL-BUTYRIC …
Matched Iupac: … acid ... (2S)-2-{[4-(2-{2-amino-4-oxo-3H,4H,7H-pyrrolo[2,3-d]pyrimidin-5-yl}ethyl)phenyl]formamido}-3-methylbutanoic …
Matched Iupac: … acid ... (2S)-2-{[4-(2-{2-amino-4-oxo-3H,4H,7H-pyrrolo[2,3-d]pyrimidin-5-yl}ethyl)phenyl]formamido}-3-methylbutanoic …
2-MERCAPTO-N-[1,2,3,10-TETRAMETHOXY-9-OXO-5,6,7,9-TETRAHYDRO-BENZO[A]HEPTALEN-7-YL]ACETAMIDE
Experimental
Matched Name: … 2-MERCAPTO-N-[1,2,3,10-TETRAMETHOXY-9-OXO-5,6,7,9-TETRAHYDRO-BENZO[A]HEPTALEN-7-YL]ACETAMIDE …
Betazole
A histamine H2 agonist used clinically to test gastric secretory function.
Approved
Matched Synonyms: … 2-(1H-pyrazol-5-yl)ethanamine …
Matched Iupac: … 2-(1H-pyrazol-5-yl)ethan-1-amine …
Matched Description: … A histamine H2 agonist used clinically to test gastric secretory function. …
Matched Salts name: … Betazole hydrochloride …
Matched Iupac: … 2-(1H-pyrazol-5-yl)ethan-1-amine …
Matched Description: … A histamine H2 agonist used clinically to test gastric secretory function. …
Matched Salts name: … Betazole hydrochloride …
Telbivudine
Telbivudine is a synthetic thymidine nucleoside analog with specific activity against the hepatitis B virus. Telbivudine is orally administered, with good tolerance, lack of toxicity and no dose-limiting side effects.
Approved
Investigational
Matched Synonyms: … 1-(2-deoxy-β-L-ribofuranosyl)-5-methyluracil …
Matched Iupac: … 1-[(2S,4R,5S)-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]-5-methyl-1,2,3,4-tetrahydropyrimidine-2,4-dione …
Matched Description: … Telbivudine is orally administered, with good tolerance, lack of toxicity and no dose-limiting side effects ... Telbivudine is a synthetic thymidine nucleoside analog with specific activity against the hepatitis B …
Matched Categories: … Nucleic Acids, Nucleotides, and Nucleosides ... Nucleosides and Nucleotides ... Nucleoside and Nucleotide Reverse Transcriptase Inhibitors ... Nucleic Acid Synthesis Inhibitors …
Matched Iupac: … 1-[(2S,4R,5S)-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]-5-methyl-1,2,3,4-tetrahydropyrimidine-2,4-dione …
Matched Description: … Telbivudine is orally administered, with good tolerance, lack of toxicity and no dose-limiting side effects ... Telbivudine is a synthetic thymidine nucleoside analog with specific activity against the hepatitis B …
Matched Categories: … Nucleic Acids, Nucleotides, and Nucleosides ... Nucleosides and Nucleotides ... Nucleoside and Nucleotide Reverse Transcriptase Inhibitors ... Nucleic Acid Synthesis Inhibitors …
Ergometrine
An ergot alkaloid with uterine and vascular smooth muscle contractile properties.
Approved
Matched Synonyms: … D-lysergic acid-L-propanolamide ... D-lysergic acid 1-hydroxymethylethylamide ... (6aR,9R)-7-Methyl-4,6,6a,7,8,9-hexahydro-indolo[4,3-fg]quinoline-9-carboxylic acid ((S)-2-hydroxy-1-methyl-ethyl …
Matched Description: … An ergot alkaloid with uterine and vascular smooth muscle contractile properties. …
Matched Salts cas: … 129-51-1 …
Matched Mixtures name: … Syntometrine Injection 5IU/1ML Ampoule …
Matched Categories: … Ergot Alkaloids and Derivatives ... Genito Urinary System and Sex Hormones ... Adrenergic alpha-Agonists ... Adrenergic alpha-1 Receptor Agonists …
Matched Description: … An ergot alkaloid with uterine and vascular smooth muscle contractile properties. …
Matched Salts cas: … 129-51-1 …
Matched Mixtures name: … Syntometrine Injection 5IU/1ML Ampoule …
Matched Categories: … Ergot Alkaloids and Derivatives ... Genito Urinary System and Sex Hormones ... Adrenergic alpha-Agonists ... Adrenergic alpha-1 Receptor Agonists …
Deserpidine
Deserpidine is an ester alkaloid drug isolated from Rauwolfia canescens (family Apocynaceae) with antipsychotic and antihypertensive properties that has been used for the control of high blood pressure and for the relief of psychotic behavior.
Approved
Matched Synonyms: … (3β,16β,17α,18β,20α)-17-methoxy-18-[(3,4,5-trimethoxybenzoyl)oxy]yohimban-16-carboxylic acid methyl ester …
Matched Description: … and antihypertensive properties that has been used for the control of high blood pressure and for the ... Deserpidine is an ester alkaloid drug isolated from Rauwolfia canescens (family Apocynaceae) with antipsychotic …
Matched Salts name: … Deserpidine hydrochloride …
Matched Categories: … deserpidine and diuretics …
Matched Description: … and antihypertensive properties that has been used for the control of high blood pressure and for the ... Deserpidine is an ester alkaloid drug isolated from Rauwolfia canescens (family Apocynaceae) with antipsychotic …
Matched Salts name: … Deserpidine hydrochloride …
Matched Categories: … deserpidine and diuretics …
Ditiocarb zinc
Ditiocarb zinc, also known as Diethyldithiocarbamic acid zinc salt, is a known chelator for copper and zinc. It also a dermatological sensitizer and allergen. Sensitivity to ditiocarb zinc may be identified with a clinical patch test.
Approved
Matched Synonyms: … Diethyldithiocarbamic acid zinc salt …
Matched Description: … Ditiocarb zinc, also known as Diethyldithiocarbamic acid zinc salt, is a known chelator for copper and ... It also a dermatological sensitizer and allergen. ... Sensitivity to ditiocarb zinc may be identified with a clinical patch test. …
Matched Categories: … Agents for Treatment of Hemorrhoids and Anal Fissures for Topical Use ... Acids, Acyclic ... Carboxylic Acids ... Compounds used in a research, industrial, or household setting …
Matched Description: … Ditiocarb zinc, also known as Diethyldithiocarbamic acid zinc salt, is a known chelator for copper and ... It also a dermatological sensitizer and allergen. ... Sensitivity to ditiocarb zinc may be identified with a clinical patch test. …
Matched Categories: … Agents for Treatment of Hemorrhoids and Anal Fissures for Topical Use ... Acids, Acyclic ... Carboxylic Acids ... Compounds used in a research, industrial, or household setting …
99mTc-HYNIC (Tyr3)-octreotide
Investigational
Matched Synonyms: … 99mtc-ethylenediamine n,n'-diacetic acid/hydrazinonicotinamide-tyr3-octreotide …
Matched Iupac: … (99Tc)technetium(5+) 2-({2-[(carboxylatomethyl)amino]ethyl}amino)acetate 4-{[(4R,7S,10S,13R,16S,19R)- …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Matched Iupac: … (99Tc)technetium(5+) 2-({2-[(carboxylatomethyl)amino]ethyl}amino)acetate 4-{[(4R,7S,10S,13R,16S,19R)- …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Displaying drugs 4451 - 4475 of 5288 in total